MRC Cancer Unit Seminars


2007-04-17 12:00: Title to be confirmed (Michael Wakelam, Babraham Institute)

2007-04-24 12:00: RNAi Functional Analysis of Drug Resistance Pathways (Charlie Swanton, Cancer Research UK London Research Institute)

2007-05-01 12:00: Dimethyl sulfoxide to vorinostat-targeted histone deacetylase inhibitor – mechanisms of action as an anti-cancer drug (Paul Marks, Sloan-Kettering Institute, New York)

2007-05-08 12:00: Germline genetic predictors of prognosis in breast cancer (Paul Pharoah, Department of Oncology, Strangeways Research Laboratories)

2007-05-15 12:00: Experimental cancer medicine at the Dana Farber Cancer Institute (Lee Nadler, Dana Farber Cancer Institute, Boston, USA)

2007-05-29 12:00: Molecular heterogeneity of breast cancer - biological and clinical implications (Carlos Caldas, CRUK Cambridge Research Institute)

2007-06-05 12:00: Novel mechanisms of clinical drug resistance in ovarian cancer (James Brenton, CRUK Cambridge Research Institute)

2007-06-12 12:00: Towards a fuller understanding of inherited susceptibility to colorectal cancer (Richard Houlston, Institute of Cancer Research, Sutton)

2007-06-19 12:00: Exploiting senescence and anoikis in function-based oncogenomic screens (Daniel Peeper, Netherlands Cancer Institute)

2007-06-26 12:00: Developments in radiotherapy: new treatments for today and tomorrow (Neil Burnet, Deptartment of Oncology)

2007-07-17 12:00: Targeting RET kinase activity as a novel therapeutic strategy for medullary thyroid carcinoma (Francesca Carlomagno, University of Naples)

2007-09-04 12:00: "Targeting the Met receptor for cancer therapy" (Ermanno Gherardi) and "Preclinical efforts in Pancreatic Cancer" (Dave Tuveson) (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Dave Tuveson (CRUK Cambridge Research Institute))

2007-09-11 12:00: Molecular genetics of MALT lymphoma: application in diagnosis and prognosis (Prof Ming Du), tbc (Prof Robert Marcus) (Robert Marcus (Addenbrooke's Hospital) and Ming Du (University of Cambridge Department of Pathology))

2007-09-18 12:00: Title to be confirmed (David Baulcombe, Sainsbury Lab, Norwich)

2007-10-09 12:00: Proteins that license DNA replication (Laskey) Clinical exploitation of proteins that license DNA replication (Coleman) (Ron Laskey and Nick Coleman (Hutchison-MRC Research Centre))

2007-10-23 12:00: Gain-of-function JAK2 mutations in the human myeloproliferative disorders (Linda Scott (Cambridge Institute for Medical Research))

2007-11-13 12:00: "High throughput mapping of cis-regulatory DNA elements: From genomic arrays to functional biology" (George Follows) & "Rapid evolutionary turnover of transcription factor binding" (Duncan Odom) (George Follows (Cambridge Institute for Medical Research) and Duncan Odom (CRUK Cambridge Research Institute))

2007-11-20 12:00: Title to be confirmed (Margaret Stanley, Department of Pathology)

2007-11-27 12:00: Progress in prostate cancer and the androgen receptor (David Neal and Ian Mills, CRUK Cambridge Research Institute)

2007-12-04 12:00: Searching for and confirming common breast cancer risk alleles (Dunning) Update on Diet and Breast Cancer (Bingham) (Alison Dunning & Sheila Bingham, Department of Oncology & MRC Dunn Human Nutrition Unit)

2007-12-18 12:00: Beyond VEGF: vascular signaling targets for therapeutic manipulation (David Quinn, University of Southern California)

2008-01-22 12:00: Acute Myeloid Leukaemia: Molecular Pathogenesis, Prognostication and Targeted therapy (Brian Huntly) (Brian Huntly (Department of Haematology, Cambridge Institute of Medical Research) & Charles Crawley (Oncology Department, Addenbrookes Hospital))

2008-01-29 12:00: "Computational biology and cancer: the CRI perspective" and "Lung Cancer: A New Strategy" (Simon Tavaré, CRUK Cambridge Research Institute and Tim Eisen, Medical Oncologist (Lung and Renal cancer), Addenbrooke's Hospital)

2008-02-12 12:00: Imaging biology in the cancer patient (K. Brindle) (Kevin Brindle (CRUK Cambridge Research Institute and Department of Biochemistry) and Athar Ahmad (Medical Oncologist, Colorectal Tumours), Addenbrooke's Hospital)

2008-02-19 12:00: Title to be confirmed (Stefanie Reichelt (CR UK Cambridge Research Institute) and Sara Booth (Palliative Care), Addenbrooke's Hospital)

2008-02-26 12:00: Experimental manipulation of the epidermis to study normal and cancer stem cells and The GIST of GISTS (Gastrointestinal Stromal tumours) (Fiona Watt, CRUK Cambridge Research Institute and Ramesh Bulusu, Clinical Oncologist (Lung/Upper GI/Lymphoma), Addenbrooke's Hospital)

2008-03-11 12:00: Title to be confirmed (Paul Pharoah (Strangeways Research Laboratories) and Rajesh Jena (Addenbrooke's Hospital)))

2008-03-18 12:00: 'Monitoring anticancer drug uptake by magnetic imaging and spectroscopy' and 'Breast cancer heterogeneity- a clinical challenge' (John Griffiths (CRUK Cambridge Research Institute) and Carlos Caldas (CRUK Cambridge Research Institute))

2008-03-25 12:00: Title to be confirmed (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Helena Earl (Medical Oncologist; Sarcoma, breast and ovarian cancer), Addenbrooke's Hospital))

2008-04-08 12:00: Breast Cancer Heterogeneity and the Cancer Stem Cell Hypothesis (John Stingl, Cambridge Research Institute)

2008-04-15 12:00: Title to be confirmed (Hugo Ford, Addenbrooke's Hospital)

2008-04-22 12:00: Chromosome translocations and gene fusions in breast cancer and Improving outcomes in melanoma: a fresh look (Paul Edwards (Hutchison/MRC Research Centre) and Pippa Corrie (Addenbrooke's Hosptial, Clinical Oncologist, Lung and Upper GI Cancer))

2008-04-29 12:00: Targeting Hyperactive Ras and Uncovering Mechanisms of Therapeutic Resistance in Genetically Engineered Mice (Kevin Shannon, University of California San Francisco)

2008-05-13 12:00: TBC (Adele Murrell, CRUK Cancer Research Institute and TBC)

2008-05-20 12:00: TBC (Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research Centre and Kate Fife, Addenbrooke's Hospital)

2008-05-27 12:00: Trials and Tribulations in the Management of Head and Neck Cancer (Sarah Jefferies, Addenbrooke's Hospital)

2008-06-09 13:00: Taming Glioblastoma -Targeting Angiogenesis (CRI Special Seminar) (Dr Steve Brem, Moffitt Cancer Center)

2008-06-10 12:00: 'Mechanisms of tamoxifen action and resistance' and 'Cambridge  Oncology - Past, Present & Future: A tour from the 18th to 21st Century' (Jason Carroll, CRI and David Gilligan, Addenbrooke's Hospital)

2008-06-17 12:00: Using Bayesian analysis in randomised phase II clinical trials to determine the worth of proceeding to phase III (Cindy Billingham, University of Birmingham)

2008-06-24 12:00: TBC (Gill Murphy, CRI and Charles Wilson, Addenbrooke's Hospital)

2008-09-02 12:00: Chromatin modifying enzymes: their function and role in cancer (Tony Kouzarides, WT/CRUK Gurdon Institute)

2008-09-03 12:00: Special seminar: Analysing the dynamic glycome (Lara Mahal, University of Texas, Austin)

2008-09-16 12:00: Early phase clinical trials in Cambridge (Duncan Jodrell, Cambridge Research Institute and Department of Oncology)

2008-09-23 12:00: Title to be confirmed (Nick Carroll, Department of Radiology)

2008-09-30 12:00: Title to be confirmed (Richard Benson, Addenbrooke's Hospital)

2008-10-14 12:00: High-throughput cancer cell line screening: a tool for discovery (Ultan McDermott, Massachusetts General Hospital Cancer Center and Harvard Medical School)

2008-10-28 12:00: The role of Fam38 in integrin activation and lung cancer (Tariq Sethi, Chair of Respiratory and Lung Cancer Biology, Centre for Inflammation Research, University of Edinburgh)

2008-11-11 12:00:  The West Anglia CLRN, TCRNs and the Coordinated System for gaining NHS Permission – How is it all going to work? (Lena Pettersson, Lead RM and G Manager, West Anglia NIHR CLRN)

2008-11-13 13:00: The Editorial Process Demystified (Andrew Sugden, International Managing Editor, Science Magazine)

2008-11-18 12:00: Colorectal neoplasia: what we know and don't know about genes and environment (John Potter, Fred Hutchinson Cancer Research Centre)

2008-11-25 12:00: The role of developmental biology in cancer research (Anna Philpott and Shin-ichi Ohnuma, Department of Oncology, MRC-Hutchison Research Centre)

2008-12-02 12:00: Delineating the Fanconi Anaemia DNA repair defect (KJ Patel, MRC Laboratory of Molecular Biology)

2008-12-09 12:00: Title to be confirmed (Rebecca Fitzgerald, Cancer Cell Unit, Hutchison/MRC Research Laboratory)

2009-01-06 12:00: Patterns of stem and progenitor cell fate in adult tissues (Professor Ben Simons, Department of Physics, Cambridge University)

2009-01-20 12:00: The evidence for lifestyle after cancer to reduce relapse and survival (Robert Thomas, Addenbrooke's Hospital)

2009-01-27 12:00: Sarcomas and the insulin-like growth factor pathway (Robert Maki, Memorial Sloan-Kettering Research Center)

2009-02-03 12:00: Role of the c-Myc-target gene Misu (NSun2) in regulating epidermal stem cell fate and its implications for cancer (Michaela Frye, Wellcome Trust Centre for Stem Cell Research, University of Cambridge)

2009-02-10 12:00: Clinical potential of functional ion channel expression in cancer (Mustafa Djamgoz, Imperial College London)

2009-02-24 12:00: The role of cyclin-kinase inhibitors in the development of cancer (Nisar Malek, Hannover Medical School, Germany)

2009-03-03 12:00: The spatial organisation of Ras signaling (Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Germany)

2009-03-10 12:00: Radiation-induced bowel damage:  let's put right what is wrong (Jervoise Andreyev, Royal Marsden Hospital)

2009-03-17 12:00: Outreach chemotherapy programme (Pippa Corrie, Addenbrooke's Hospital)

2009-03-24 12:00: What comes after cancer stem cells? (Doug Winton, CRUK Cambridge Research Institute)

2009-03-31 12:00: Analysis of early events after DNA damage in living cells; the HP1 paradigm (Anand Jeyasekharan, Hutchison/MRC Research Centre)

2009-04-07 12:00: Connecting Lung Epithelial Stem Cells and Lung Cancer by Stress-Activated Protein Kinases (Juan Jose Ventura, Wellcome Trust Centre for Stem Cell Research, University of Cambridge)

2009-04-21 12:00: Preservation of fertility in patients with cancer (Raj Mathur (Addenbrooke's Hospital) and Tom Mathews (Medical Director, Bourn Hall))

2009-04-28 12:00: OPCML in Tumour Gene Therapy in Ovarian Cancer (Hani Gabra, Faculty of Medicine, Imperial College London)

2009-05-05 12:00: Taming the tiger by the tail:  modulation of DNA damage responses by telomeres (David Lydall, Institute for Ageing and Health, Newcastle University)

2009-05-19 12:00: Common germline variation and colorectal cancer (Richard Hubner, Royal Marsden Hospital)

2009-05-26 12:00: Using genetics to personalize melanoma therapy (Keiran Smalley, Moffitt Cancer Center)

2009-06-02 12:00: A model for all genomes: the role of RNA polymerases fixed in factories (Peter Cook, University of Oxford)

2009-06-09 12:00: Translational imaging studies in ovarian cancer (James Brenton, CRUK Cambridge Research Institute and Evis Sala, Department of Radiology)

2009-06-16 12:00: Is brain cancer a stem cell disease? (Colin Watts, Department of Clinical Neurosciences)

2009-06-23 12:00: Germ Cell Tumours (GCTs) of Young People: Clinical and Biological Approaches (James Nicholson and Matthew Murray, Paediatrics, Addenbrooke's Hospital)

2009-06-30 12:00: Genome scans in breast and prostate cancer - what have we learned & where next? (Doug Easton, Strangeways Research Laboratory)

2009-09-08 12:00: Adoptive T Cell Therapy of Cancer (Cassian Yee, Fred Hutchinson Research Center, Seattle)

2009-09-15 12:00: Clinical Aspects of Proton Radiotherapy (Prof Tony Lomax, Head of Medical Physics, Centre for Proton Radiation Therapy, Paul Scherrer Institute, Switzerland)

2009-09-29 12:00: Molecular Mechanisms of Cellular Senescence in Cancer and Ageing (Fabrizio d'Adda di Fagagna, IFORM-IEO, Milan)

2009-10-13 12:00: "Immunostimulatory antibodies in cancer treatment" (Prof. Peter Johnson, Professor of Medical Oncology, University of Southampton)

2009-10-20 12:00: "Phospholipase and lysophospholipase D signalling in cancer" (Prof. Michael Wakelam, Institute Director, The Babraham Institute)

2009-10-27 12:00: Steroid Hormone Receptors in Prostate Cancer: A Hard Habit to Break? (Dr Gerhardt Attard, The Institute of Cancer Research and the Royal Marsden Hospital)

2009-11-03 12:00: The irreversibility of cell cycle transitions: why the clock never turns back (Frank Uhlmann, CRUK London Research Institute)

2009-11-17 12:00: "The Arguments for and against Sentinel Node Biopsy (SNB) in Melanoma" (Prof. J Meirion Thomas, Royal Marsden Hospital & Imperial College, London)

2009-11-24 12:00: “Intensity modulated radiotherapy for children’s tumours and estimation of the carcinogenic risk” (Dr Michael Williams & Dr Gail Horan, Addenbrooke's Hospital)

2009-12-01 12:00: Cellular senescence: molecular mechanisms and implications for cancer and aging (Peter Adams, Beatson Institute for Cancer Research, Glasgow)

2009-12-15 12:00: The new LAW of microRNA-mediated gene silencing: implications for lung cancer development (Dr Tyson V. Sharp, School of Biomedical Sciences, University of Nottingham)

2010-01-12 12:00: PREDICT: A NEW UK PROGNOSTIC MODE THAT PREDICTS SURVIVAL FOLLOWING SURGERY FOR INVASIVE BREAST CANCER (GC Wishart, EM Azzato, PDP Pharoah, DC Greenberg, J Rashbass, O Kearins, G Lawrence, C Caldas C, PM Ravdin) (Prof. Gordon Wishart, Addenbrooke's Hospital)

2010-01-19 12:00: Investigating the interaction of Radiotherapy & Temozolomidefor Glioblastoma (Dr Raj Jena, Addenbrooke's Hospital)

2010-01-26 12:00: HPV vaccines - will they do their job? (Prof. Margaret Stanley, Dept. of Pathology, University of Cambridge)

2010-02-02 12:00: Can we age in utero? Can we kill cancer cells by making them replicate faster? And other ATR stories… (Oscar Fernandez-Capetillo, Spanish National Cancer Research Centre (CNIO))

2010-02-09 12:00: High-throughput Cancer Cell line Screens: Linking Drug Response to Molecular Signatures (Dr Ultan McDermott, Cancer Genome Project, Wellcome Trust Sanger Institute)

2010-02-16 12:00: The prognostic significance of subtypes of breast cancer classified using immunohistochemistry (Dr Paul Pharoah, Strangeways Research Laboratory/Oncology)

2010-02-23 12:00: CANCELLED (Dr Alison Dunning, Strangeways Research Laboratory & Dept. of Oncology)

2010-03-02 12:00: The Role of the Receptor Tyrosine Kinase Antagonist, Lrig1, in Normal Tissue Homeostasis and Cancer (Kim Jensen, Anne McLaren Laboratory for Regenerative Medicine and Department of Oncology)

2010-03-09 12:00: "The Fine Scale Mapping of Breast Cancer Loci found via GWAS - searching for the Causative Variants" (Dr Alison Dunning, Strangeways Research Laboratory)

2010-03-16 12:00: Deciphering the Mammary Epithelial Cell Hierarchy (Dr John Stingl, CRUK Cambridge Research Institute)

2010-03-30 12:00: "Non-Invasive Diagnosis of Brain Cancer" (Prof. John Griffiths, CRUK Cambridge Research Institute)

2010-04-13 12:00: CANCELLED (Dr James Brenton, CRUK Cambridge Research Institute)

2010-04-20 12:00: The NCAG Report: Delivering a World Class Chemotherapy Service (Prof Roger James, Previously:  • Deputy Medical Director Maidstone and Tunbridge Wells NHS Trust   • Medical Director Kent & Medway Cancer Network)

2010-04-27 12:00: “Macromolecular interactions in the control of chromosome instability” (Prof. Ashok Venkitaramann, (Hutchison-MRC Research Centre))

2010-05-04 12:00: Mechanisms regulating neural differentiation (Kate Storey, University of Dundee)

2010-05-11 12:00: "Cellular Senescence as a Tumour Suppressor Mechanism, Particular Focus will be on the Autophagy/mTOR Pathway" (Dr Masashi Narita, CRUK Cambridge Research Institute)

2010-05-18 12:00: "Stem cell identity and mRNA export: unexpected roles of geminin and GANP" (Prof. Ron Laskey, Hutchison/MRC Research Centre)

2010-05-25 12:00: "A New Window of Opportunity in Prostate Cancer" (Dr Danish Mazhar, Addenbrooke's Hospital)

2010-06-15 12:00: Dynamic Notch signaling in neural progenitor cells (Ryoichiro Kageyama, Kyoto University, Japan)

2010-06-22 12:00: "Gastro Intestinal Stroma Tumours (GISTS)" (Dr Ramesh Bulusu, Addenbrooke's Hospital)

2010-06-29 12:00: "Breast Radiotherapy - Past, Present and Future" (Dr Charlotte Coles, Addenbrooke's Hospital)

2010-09-07 12:00: Unravelling cancer cell signalling networks and screening for novel drug targets (Daniel Peeper, The Netherlands Cancer Institute)

2010-09-14 12:00: Interactions of Epidermal Growth Factor Receptor Inhibition with DNA damage in the treatment of gastrointestinal cancer (Prof Daniel Hochhauser, University College London)

2010-09-21 12:00: Pathway Analysis of Glioblastoma Tissue After Preoperative Treatment with the EGFR Tyrosine Kinase Inhibitor Gefitinib – A Phase “0 Trial” (Dr Monika Hegi, University Hospital (CHUV), Lausanne, Switzerland)

2010-09-28 12:00: “EGFR Mutation Screening in NSCLC” (Dr David Gonzalez de Castro, The Institute of Cancer Research and Royal Marsden Hospital)

2010-10-12 12:00: "Imaging Tumour Cell Death" (Prof. Kevin Brindle, CRUK Cambridge Research Institute)

2010-10-19 12:00: "Brain Metastases – a cross cutting theme: Review of the Brain Metastasis Service and Future Research Potential" (Dr Sarah Jefferies, Addenbrooke's Hospital)

2010-10-26 12:00: "Chromosome Translocations and Tumour Suppressors in Breast Cancer" (Dr Paul Edwards, Hutchison/MRC Research Centre)

2010-11-23 12:00: Targeting NG2 Cells in Glioblastoma (Dr Colin Watts, Cambridge Centre for Brain Repair)

2010-11-30 12:00: "Susceptibility to Cancer - What's New?" (Prof Doug Easton, Strangeways Research Laboratory)

2010-12-02 14:30: Neuroblastoma- Disordered Developmental Programs Contribute to Tumorigenesis (Prof Carol Thiele, National Cancer Institute, USA)

2010-12-14 12:00: RCC Cinderella comes of age (Prof. Tim Eisen, Dept. of Oncology, University of Cambridge & Addenbrooke's Hospital)

2010-12-21 12:00: “Breast MRI by  the Shutter-Speed Method: Elimination of Unnecessary Breast Biopsies" (Dr Charles S. Springer, Jr., Advanced Imaging Research Centre. Oregon Health & Science University)

2011-01-25 12:00: "Leukaemia stem cells: how normal stem cell function is subverted in haematological malignancies" (Dr Brian Huntly, Department of Haematology)

2011-02-01 12:00: Application of Systems Biology Approaches to Study Cell Signalling and Transcription (Prof Mike White, University of Liverpool)

2011-02-15 12:00: "Targetting pre-neoplasia in the bronchus" (Dr Robert Rintoul, Papworth Hospital)

2011-02-22 12:00: Mesothelioma: a disease of our time (Dr David Gilligan, Addenbrooke's Hospital)

2011-03-08 12:00: "FGF-2, S6 Kinase 2 and Chemo-resistance in Lung Cancer" (Prof. Michael Seckl, Imperial College, London and Charing Cross Hospital)

2011-03-15 12:00: "The Cambridge breast cancer program- recent progress" (Dr Carlos Caldas, CRUK Cambridge Research Institute)

2011-04-12 12:00: "Somatic Genetics of Human Cancer - Moving Towards Large Scale Resequencing of Cancer Genomes" (Dr Andy Futreal, The Wellcome Trust Sanger Institute, Hinxton)

2011-04-26 12:00: CANCELLED (Dr Vincent Gnanapragasam, Hutchison/MRC Research Centre & Addenbrooke's Hospital)

2011-05-03 12:00: CANCELLED (Prof Sibylle Mittnacht, The Institute of Cancer Research)

2011-05-10 12:00: "Multi-site post-translational modification as a quantitative regulator of transcriptional output during neurogenesis" (Dr Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre)

2011-05-17 12:00: CANCELLED (Prof. Roy Rampling, University of Glasgow and The Beatson Cancer Centre, Glasgow)

2011-05-24 12:00: “What lessons can we learn from transcriptional evolution in cancer research?” (Dr Duncan Odom, CRUK Cambridge Research Institute)

2011-05-31 12:00: SOCCAR trial: an update (Dr Joe Maguire, Consultant Clinical Oncologist, Clatterbridge Centre for Oncology)

2011-06-07 12:00: "Developing Medicines for Pancreatic Cancer" (Dr Dave Tuveson, CRUK Cambridge Research Institute)

2011-06-14 12:00: "Advances in Head and Neck Radiotherapy" (Dr Chris Nutting, Royal Marsden Hospital)

2011-06-21 12:00: ‘Viral and host contributions to cervical carcinogenesis’ (Dr Nick Coleman, Department of Pathology & Hutchison/MRC Research Centre)

2011-06-28 12:00: The ATM-mediated DNA damage response: moving between the forest and the trees (Dr Yossi Shiloh, Tel Aviv University, Israel)

2011-09-06 12:00: Haploid Genetic Screens in Human Cells (Dr Thijn Brummelkamp, Netherlands Cancer Institute)

2011-09-20 12:00: DNA repair inhibitors in cancer treatment (Prof Hilary Calvert, UCL Cancer Institute)

2011-10-04 12:00: Tumour-stroma Interactions in Breast Cancer (Prof Clare Isacke, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research)

2011-10-18 12:00: ‘Genetic predisposition to cancer’ (Prof Bruce Ponder, Cancer Research UK Cambridge Research Institute)

2011-11-01 12:00: Cancer Gene Discovery in the Mouse (Dr David Adams, Wellcome Trust Sanger Institute)

2011-12-06 12:00: Integration of Cell Growth and Cell Metabolism by Myc (Prof Martin Eilers, Theodor-Boveri-Institute, University of Würzburg, Germany)

2011-12-13 12:00: Neo-adjuvant radiochemotherapy in breast cancer (Dr Alain Fourquet, Department of Radiation Oncology, Institut Curie, Paris)

2012-01-24 12:00: “Imaging Biomarkers in Cancer” (Prof. Fiona Gilbert, Dept. of Radiology)

2012-02-07 12:00: Transcriptional control of EMT and malignant tumor progression (Prof Gerhard Christofori, University of Basel, Switzerland)

2012-02-14 12:00: "Radiotherapy toxicity, Radiogenomics and RAPPER" (Dr Gill Barnett, Dept. of Oncology)

2012-02-21 12:00: "Myeloproliferative neoplasms – JAK/STAT signalling and stem cell subversion" (Prof Tony Green, University of Cambridge Department of Haematology)

2012-02-28 12:00: "DICER1 and miRNA processing - a novel paradigm in  cancer predisposition" (Dr Marc Tischkowitz, Dept of Medical Genetics, University of Cambridge)

2012-03-13 12:00: "Re Service Reforms in the new Commissioning Landscape" (Hannah Farrar, Director of Strategy and System Management, NHS, London)

2012-03-20 12:00: "Thalidomide and its analogues ; How molecules selected for anti-TNFa activity affect so many different pathways with direct binding with Cereblon mediating both anti proliferative and Immunomodulatory functions" (Jerome B. Zeldis CEO of Celgene Global Health & Angus Dalgleish, St George's Hospital London)

2012-03-27 11:30: "Exploiting ASS1 deficiency in the treatment of mesothelioma" (Dr Peter Szlosarek, Cancer Research UK Clinician Scientist, Senior Lecturer and Honorary Consultant in Medical Oncology, Barts and The London)

2012-04-03 12:00: Always on guard: p53 dynamics in single living cells (Dr Alexander Loewer, Berlin Institute for Medical Systems Biology, Max Delbrueck Center, Germany)

2012-04-24 12:00: CANCELLED (Prof Richard Sullivan, Professor, Kings College London, Director, Centre for Global OncoPolicy & Health Kings Health Partners)

2012-05-03 17:00: ALK Hunting in Colorado - new drugs for lung cancer's new diseases (Dr Ross Camidge,  University of Colorado Hospital (UCH) and the University of Colorado Cancer Center,)

2012-05-08 12:00: Investigating key effectors downstream of APC (adenomatous polyposis coli)  deletion in vivo (Prof Owen Sansom, Beatson Institute, Glasgow)

2012-05-15 12:00: "Strategies to enhance effectiveness of Radiotherapy in Pancreatic Cancer" (Dr Thomas Brunner, Gray Institute for Radiation Oncology and Biology, Oxford)

2012-05-29 12:00: Pancreatic cancer: Genetic models to develop novel diagnostic and therapeutic strategies (Dr Dieter Saur, The Technical University of Munich)

2012-06-12 12:00: Cancer-related inflammation (Dr Thorsten Hagemann, Barts Cancer Institute, Queen Mary University of London)

2012-06-21 16:00: Understanding Response & Resistance Mechanisms to Targeted Therapy (Dr Keith Flaherty, Director of Developmental Therapeutics at Massachusetts General Hospital)

2012-08-14 12:00: 'Circulating Tumour Cells: Biomarker Utility and Insights to Metastasis' (Professor Caroline Dive, Clinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester)

2012-11-06 12:00: Signalling Networks in Cell Proliferation and Fate Control (Professor Sibylle Mittnacht, UCL Cancer Institute)

2012-11-06 16:00: A genomic Odyssey of predicting drug response: is Ulysses home yet? (Dr Federico Innocenti, UNC Institute for Pharmacogenomics and Individualized Therapy)

2012-11-07 10:30: A systems view of the cancer cell: from missing genetic variability to combination therapy (Andrea Califano, Columbia University)

2012-11-13 12:00: "Towards personalized medicine in Breast Cancer" (Prof. Dr. Sabine C. Linn, medical oncologist Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands)

2012-11-20 12:00: Mechanisms of Estrogen Receptor Transcription in Breast Cancer (Dr Jason Carroll, CRUK Cambridge Research Institute)

2012-11-27 12:00: Cellular responses to DNA damage:  translating molecular insights towards new cancer therapies (Prof Steve Jackson, Head of Cancer Research UK Laboratories The Gurdon Institute, Cambridge)

2012-12-04 12:00: Localisation-based feedback controls during mitosis and the maintenance of chromosomal stability (Dr Adrian Saurin, University Medical Center Utrecht, The Netherlands)

2013-02-05 12:00: Telomeres and the challenges to chromosome integrity (Dr Julie Cooper, London Research Institute)

2013-02-19 12:00: Challenges in Implementing Personalized Cancer Medicine: the IGR experience (Professor Alexander Eggermont, Director General, Institut de Cancérologie Gustave Roussy, France)

2013-03-12 12:00: CANCELLED  (Dr Fiona Blackhall, Manchester University, Manchester Cancer Research Centre Lung Group Lead)

2013-04-23 12:00: “The identification of patients who benefit from targeted therapy in renal cancer” (Professor Thomas Powles, Barts Cancer Institute, Queen Mary University of London)

2013-05-07 12:00: Macrophages Into Tumor Hypoxic Areas: Should I Stay Or Should I Go? (Dr Massimiliano Mazzone, VIB Vesalius Research Center, Belgium)

2013-05-14 12:00: ‘CLL – from chemotherapy to targeted kinase inhibition’ (Dr George Follows, Consultant Haematologist, Addenbrooke's )

2013-05-28 12:00: "Renal Cancer and Oxygen Sensing" (Prof Patrick Maxwell, Regius Professor of Physic, University of Cambridge)

2013-06-04 12:00: Control of cytokinesis and the dark side of actomyosin forces (Dr Mark Petronczki, London Research Institute)

2013-06-11 12:00: Economics of Cancer Medicines (Professor Richard Sullivan, Guy's Hospital, London)

2013-06-25 12:00: "Image guidance – benefits and risks" (Professor Marcel van Herk, Imaging Physicist, Project Leader, The Netherlands Cancer Institute)

2013-07-02 13:00: Genetic modifiers and microenvironmental control of tumor invasiveness (Prof Douglas Hanahan, EPFL, Switzerland )

2013-07-16 12:00: Risk and uncertainty in radiotherapy.  Why I am the weakest link? (Dr Tom Roques, Lead of Head and Neck Cancer Multidisciplinary Team, Norfolk and Norwich Hospital)

2013-09-03 12:00: Insights  for the role of  tumour-related inflammation and stem cells in Drosophila (Dr Marcos Vidal, Beatson Institute, Glasgow )

2013-09-10 12:00: Advances in non-surgical treatment for cervix cancer (Dr Li Tee Tan, Addenbrooke's )

2013-09-24 12:00: CANCELLED  (Professor Charles Swanton, CRUK & UCL Trials Centre, UCL)

2013-10-01 12:00: Target-Based Approach in Early-Phase Clinical Trials in Cancer (Filip Janku, Investigational Cancer Therapeutics, (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, Houston)

2013-10-08 12:00: Spotlight on Cambridge Clinical Trials; Presentations from the American Society of Oncology (ASCO) Annual Meeting 2013 (Prof Tim Eisen, Dr Hugo Ford, Dr Pippa Corrie & Dr Kate Fife)

2013-10-29 12:00: CANCELLED -   Scottish Collaboration On Translational Research into Renal Cell Cancer, developing a systems medicine approach to personalised treatment (Mr Grant Stewart, Department of Urology and Edinburgh Urological Cancer Group,Western General Hospital. Edinburgh)

2013-11-04 16:00: The p53 pathway: 21 years of  the "guardian of the genome" (Prof Sir David Lane, Chief Scientist, A*STAR, Singapore)

2013-11-26 12:00: "The Cambridge Breast Cancer Programme" (Prof Carlos Caldas, CRUK Cambridge Research Institute)

2013-12-03 12:00: The autophagy signaling network in the coordination of a cell's response (Prof Francesco Cecconi, University of Tor Vergata, Italy )

2013-12-17 12:00: CANCELLED  (Prof Josep Tabernero, Head, Medical Oncology Department, Vall d' Hebron University Hospital, Barcelona, Spain)

2014-01-07 12:00: Chasing metabolic alterations in cancer (Dr Arkaitz Carracedo, CIC bioGUNE,  (Center for Cooperative Research in Biosciences), Derio, Spain)

2014-01-14 12:00: Personalized medicine initiative at Gustave Roussy ( Professor Jean-Charles SORIA - Chef de Service, Professor of Medicine and Medical Oncology, Paris University XI and cancer specialist at Institut Gustave, Roussy.)

2014-02-04 12:00: Translating Tumour Metabolism into New Diagnostics and Novel Anti-Cancer Therapeutics (Professor Michael Lisanti, Director of the Breakthrough Breast Cancer Research Unit, University of Manchester)

2014-02-11 12:00: “What can we do to accelerate the discovery of new medicines for patients?” (Professor Chas Bountra, Head of Structural Genomics Consortium, University of Oxford, Nuffield Dept of Clinical Medicine )

2014-03-04 12:00: Cell death and autophagy in response to inhibition of glycolysis (Dr Cristina Muñoz Pinedo, IDIBELL, Barcelona, Spain)

2014-04-01 12:00: “Personalized Medicine in Oncology: The Dutch experience” (Professor Jaap Verweij, Erasmus MC Cancer Institute, Weytemaweg 80, 3105 CN Rotterdam, The Netherlands)

2014-04-08 12:00: Targeting bioenergetics in hypoxic and rapidly growing tumours (Dr Jacques Pouysseggur, Institute of Research on Cancer and Ageing (IRCAN), Nice, France)

2014-04-09 11:00: Centrosome changes in cancer – causes and consequences (Monica Bettencourt Dias, Instituto Gulbenkian de Ciência)

2014-05-06 12:00: Spatio-temporal control of RhoGTPases and the cytoskeleton in invading cancer cells by integrins and endocytic trafficking (Dr Patrick Caswell, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester)

2014-05-13 12:00: "From trials evaluating drugs to trials evaluating treatment algorithms – Focus on the SHIVA trial" (Dr Christophe Le Tourneau, Medical Oncologist, Head of the Phase I Program at the Institut Curie, Paris, France,)

2014-05-20 12:00: Personalised Cancer Medicine. How do we get there? (Dr Helena Earl, Dept. of Oncology, University of Cambridge)

2014-06-03 12:00: Undermining Myc: Mitochondria Hold the Key (Dr Daniel Murphy, Institute of Cancer Sciences, University of Glasgow)

2014-06-10 12:00: Breast Imaging research in Cambridge (Professor Fiona Gilbert, Head of Department of Radiology, Cambridge)

2014-06-24 12:00: Precision Cancer Prevention: Trying to use Genomics to Save Lives (John Hopper, Professor & Director (Research), Centre for Molecular, Environmental, Genetic and Analytic (MEGA) Epidemiology, University of Melbourne, Australia)

2014-06-27 13:45: Noninvasive cancer genomics (Nitzan Rosenfeld, Cancer Research UK Cambridge Institute)

2014-07-22 12:00: 'Scottish Collaboration On Translational Research into Renal Cell Cancer (SCOTRRCC): a springboard for renal cancer biomarker development’.  (Mr Grant Stewart, Clinical Senior Lecturer and Honorary Consultant in Urological Surgery, University of Edinburgh )

2014-07-28 14:45: Cellular hierarchies in normal and malignant epithelial tissue (John Stingl, Cancer Research UK Cambridge Institute)

2014-09-09 12:00: “Paradigm changes produced by targeted agents in Phase I trials in Oncology. Case studies of a TFbeta inhibitor and a Sonic Hedgehog inhibitor” (Dr Jordi Rodon, Head of Research Unit for Molecular Therapy of Cancer Oncology Department. Vall D’Hebron University Hospital, Barcelona, Spain)

2014-10-07 12:00: The role of stem cells in the pathogenesis of hepato-biliary cancers (Professor Nisar Malek, University of Tubingen, Germany)

2014-10-07 12:00: “CDD’s new Research Strategy” (Dr Nigel Blackburn, Director of Centre for Drug Development, Cancer Research UK)

2014-10-14 12:00: CANCELLED -      Lung cancer, biomarkers and unanswered questions - a clinical translational perspective (Dr Fiona Blackhall, Consultant Medical Oncologist, The Christie Hospital, Manchester                    )

2014-10-21 12:00: "The role of epigenetic regulators and their therapeutic targeting in Acute Myeloid Leukaemia and haematological malignancies” (Dr Brian Huntly, Department of Haematology, Cambridge University)

2014-11-11 12:00: “Stratified Medicine in Cancer Therapy - a practical guide” (Professor Gary Middleton, Professor in Medical Oncology, School of Cancer Sciences, University of Birmingham)

2014-11-18 12:00: Tracking genomic aberrations of the androgen receptor (AR) in castration-resistant prostate cancer (CRPC) (Dr Gerhardt Attard, Royal Marsden Hospital, London)

2014-11-19 12:00: Cell fate in response to anti-mitotic chemotherapeutics (Professor Stephen Taylor, Faculty of Life Sciences, University of Manchester)

2014-12-02 12:00: In vivo function-based genomic approaches for cancer drug target discovery  (Professor Daniel Peeper, Head, Division of Molecular Oncology, The Netherlands Cancer Institute)

2014-12-16 12:00: Ovarian Cancer in Transition (Mr Douglas Levine, Gynecology Service, Department of Surgery)

2015-01-13 12:00: Explaining the reduction in ovarian cancer mortality 1977 to 2014 (Dr Steven Narod, Director, Familial Breast Cancer Research Unit, Women's College Research Institute, Toronto, Canada)

2015-01-27 12:00: “Optimizing Image Guided Radiotherapy for Patient Benefit” (Dr Peter Remeijer, Medical Physicist NKI /Avl, Amsterdam)

2015-02-03 12:00: MYC Oncoproteins act as Epigenetic Modifiers (Dr Frank Westermann, Research Group Neuroblastoma Genomics, DKFZ, Heidelberg)

2015-03-03 12:00: Systems Biology of Cancer (Professor Jussi Taipale, Department of Biosciences and Nutrition, Karolinska Institute, Sweden )

2015-04-14 12:00: Defining treatment paradigms in prostate cancer; the UK as a dominant force - past, present, and future (Professor Malcolm Mason, NCRI Prostate Cancer Clinical Studies Group and School of Medicine, Cardiff University)

2015-05-05 12:00: Metastatic Stem Cells, TGF-beta signalling and poor-prognosis in CRC (Dr Eduard Batlle (Group Leader, Institute for Research in Biomedicine, Barcelona))

2015-05-12 12:00: "Designing trials to find the right dose" (Dr Adrian Mander - Director of MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge)

2015-05-19 12:00: DNA damage response: Mechanisms and relevance for cancer development and treatment (Professor Jiri Bartek, The Danish Cancer Society Research Center Genome Integrity Unit, Denmark)

2015-06-02 12:00: 'ECM remodelling during cancer progression' (Dr Janine Erler, Associate Professor - Biotech Research & Innovation Centre (BRIC),Copenhagen )

2015-06-09 12:00: 'Harnessing hypoxia signalling in cancer' (Professor Margaret Ashcroft, Cambridge Cardiovascular)

2015-06-23 12:00: Interrogating the Architecture of Cancer Genomes (Dr Peter Campbell,  Head of Cancer Genome Project, Wellcome Trust Sanger Institute.)

2015-07-07 11:00: ‘Novel dual-action combination therapy enhances angiogenesis whilst reducing tumour growth and spread’ (Professor Kairbaan Hodivala-Dilke, Professor of Angiogenesis, Deputy Institute Director QMUL )

2015-09-08 12:00: CANCELLED -                                                           "Synergistic effect of radiotherapy and cis-platinum chemotherapy delivered via gold nanoparticles in glioblastoma multiforme" (Dr Sara Piccirillo, Department of Clinical Neurosciences and Alexandra Vaideanu, Deptatment of Engineering )

2015-09-15 12:00: Genomics of radiation responses and radiosensitivity (Professor Michael McKay, North Coast Cancer Institute, NSW, Australia)

2015-10-13 12:00: Melanoma and the translational cycle of innovation in cancer therapeutics (Professor Grant McArthur, Peter MacCallum Cancer Centre, Victoria, Australia)

2015-11-17 11:30: Intrinsic and extrinsic determinants of pancreatic cancer stem cells (Professor Christopher Heeschen, Centre Lead, Centre for Stem Cells in Cancer and Ageing, Barts Cancer Institute, London)

2015-11-24 12:00: "Tumor-­induced reprogramming of hepatic metabolism disrupts anti‐tumor immunity” (Dr Tobias Janowitz, Department of Oncology)

2015-12-08 12:00: ‘Combine and conquer: critical pre-clinical and clinical aspects of targeted anti-cancer drugs’ (Dr Udai Banerji, Drug Development Unit, ICR)

2016-02-23 12:00: Innate Genetics and the Tumour Microenvironment Cooperate to Drive Prostate Cancer Aggression (Prof Robert G Bristow, Senior Scientist, Princess Margaret Cancer Centre, Toronto)

2016-03-09 17:00: “New Developments in Molecular Imaging of Prostate Cancer” (Professor Wim Oyen, Professor of Nuclear Medicine and Molecular Imaging, ICR, London)

2016-03-15 12:00: “Why Determining Pathogenicity in the Age of Precision Medicine, will Require More than Analyzing Genomic Sequences” (Dr Bruce Gottlieb, Lady Davis Institute for Medical Research, Segal Cancer Centre, Jewish General Hospital, Department of Human Genetics, Department of Medicine, McGill University, Montreal, Canada)

2016-05-03 11:30: “Mechanisms of MYC-driven genome instability” (Jean Gautier, Professor of Genetic and Development, Institute for Cancer Genetics, Columbia University, New York (USA))

2016-05-17 12:00: Future of medicines development: capabilities and how industry is evolving and interacting with academia and the NHS  (Andrew Hughes, Professor of Experimental Cancer Medicine,The Christie NHS Foundation Trust, Manchester)

2016-06-09 12:30: Computational Radiotherapy Symposium, 2016: personalised radiotherapy, or how computers can cure cancer (Speakers as detailed in Symposium Programme)

2016-06-28 12:00: Mechanisms of lymphomagenesis: Developmental origins of a paediatric cancer (Dr Suzanne Turner, Department of Pathology)

2016-07-05 11:30: "Mechanisms of colon cancer initiation, progression and metastasis" (Joerg Huelsken, Associate Professor, Debiopharm Chair in Signal Transduction in Oncogenesis, EPFL, Lausanne)

2016-11-29 12:00: CANCELLED - Impact of the Microbiome on cancer and its treatment (Dr Trevor Lawley, Group Leader, Host-Microbiota Interactions Laboratory, Wellcome Trust Sanger Institute)

2017-02-07 11:30: The interaction between tumor hypoxia and DNA methylation  (Dr Bernard Thienpont, VIB-KU Leuven Center for Cancer Biology, KU Leuven, Belgium)

2017-03-07 11:30: ‘Non-coding RNA - new roles for old players’ (Professor Anders Lund, Biotech Research and Innovation Centre, University of Copenhagen)

2017-05-02 11:30: ‘Alterations of the Polycomb machinery in cancers’ (Raphaël Margueron, Curie Institute, Paris)

2017-05-25 15:00: 'Analyses for Rule-Based Models of Cellular Signalling' (Dr Jean Yang, Assistant Professor,Department of Computer Science, Carnegie Mellon University, Pittsburgh USA )

2017-06-06 11:30: ‘Exploring and exploiting aberrant self-fate programs in leukemia’ (Dr Johannes Zuber, Research Institute of Molecular Pathology (IMP), Vienna, Austria)

2017-06-26 15:00: Satellite RNAs, Heterochromatin and Cancer: A Novel Mechanism of Induction of Breast Cancer by Loss of BRCA1? (Professor Inder Verma, Salk Institute, San Diego, USA )

2017-09-18 14:00: ‘The role of Mre11 in DNA double strand break repair  -  myth and facts’ (Professor Shunichi Takeda, Department of Radiation Genetics, Kyoto University)

2017-11-07 11:30: Metastasis latency: new molecular insights (Roger Gomis, ICREA Research Professor, IRB Barcelona)

2017-12-05 11:30: ‘Tracking metabolic reprogramming in cancers with PI3K/Akt activation’ (George Poulogiannis, Team Leader, Division of Cancer Biology, Institute of Cancer Research, London)

2018-02-06 14:30: Oxidative Stress Defences in Cancer (Professor Joan Brugge, Louise Foote Pfeiffer Professor of Cell Biology and Director of the Ludwig Centre at Harvard University)

2018-03-06 11:30: ‘Instituting Molecular Precision in Localised Prostate Cancer - A Cure for All?’ (Rob Bristow, University Professor of Cancer Studies, Director of MCRC)

2018-03-20 12:00: "Proton Beam Therapy: Current and Future Provision" (Yen-Ching Chang, Consultant in Clinical Oncology, UCHL)

2018-05-03 11:00: ‘Accelerating the translation of mutational signatures' (Dr Serena Nik-Zainal, Wellcome Sanger Institute)

2018-06-05 11:00: ‘Cellular Plasticity in Cancer:  driving force and therapeutic target’ (Professor Thomas Brabletz, Department of Experimental Medicine, University Erlangen-Nuernberg)

2018-06-15 10:30: ‘Nuclear Mechanopathology & Early Cancer Diagnostics’ (Professor GS Shivashankar, Deputy Director, Mechanobiology Institute, National University of Singapore)

2018-12-04 11:30: ‘Executable Disease Networks: Reconstruction, Topology, Dynamics’ (Anna Niarakis, Université Paris-Saclay, Evry, France)

2019-01-15 11:30: THIS SEMIAR IS NOW CANCELLED  -                                                            'Cell Plasticity in Colon Carcinogenesis' (Professor Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frankfurt)

2019-02-27 12:00: ‘Multi-dimensional cancer-immune cell interaction during metastasis’ (Xiang Zhang, Baylor College of Medicine, Houston, USA)

2019-04-09 11:30: ‘Mammary epithelial cell fate and tumour initiation at the single cell resolution’ (Walid Khaled, Department of Pharmacology, University of Cambridge)

2019-05-07 11:30: ‘New protagonists of the tumour microenvironment’ (Dr Ilaria Malanchi, Tumour-Host Interaction Lab,Francis Crick Institute, London )

2019-06-11 11:30: ‘Next-Generation Biopsies in Gastrointestinal Cancers’ (Dr Nicola Valeri, Institute of Cancer Research and The Royal Marsden NHS Trust)

2019-06-11 12:00: ‘Why Standard Naming and Pixel-based Contouring/Voluming are important to research in the radiation Oncology area’ (Prof Andrew Miller, Radiation Oncologist, Illawarra Cancer Care Centre, Wollongong, NSW Australia / Adjunct Professor of Informatics, School of Informatics, University of Wollongong  )

2019-07-01 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Institute for Tumor Biology and Experimental Therapy Frankfurt)

2019-07-10 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Heidelberg University, Faculty of Medicine & EMBL- Heidelberg University Molecular Medicine Partnership Unit)

2019-09-03 11:30: ‘Treatment of cancer by inhibition of mtDNA gene expression’ (Nils-Göran Larsson, MD, PhD, Professor, Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm )

2019-10-01 11:30:  ‘Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis’ (Professor Albena Dinkova-Kostova,Jacqui Wood Cancer Centre, Division of Cellular Medicine, University of Dundee  )

2019-12-03 11:30: ‘Cell Plasticity in Colon Carcinogenesis’ (Professor Dr Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frakfurt)

2020-04-07 11:30: CANCELLED - “Cancer genomics: from chromatin structure to new therapeutic targets” (Professor Elisa Oricchio (EPFL, Zurich))