CRUK CI website talks listing 2008-03-07 12:00: Functional Heterogeneity of Mouse Hematopoietic Stem Cells (Brad Dykstra, University Medical Center Groningen, The Netherlands) 2008-03-13 12:00: Understanding the self-renewal ability of mouse embryonic stem (ES) cells through single cell mRNA and microRNA profiling approach (Fuchou Tang, The Wellcome Trust/Cancer Research UK Gurdon Institute) 2009-05-27 15:00: Characterisation of structural variation in 24 breast cancer genomes using paired-end sequencing on the Illumina Genome Analyser (Phil Stevens, Wellcome Trust Sanger Institute) 2009-06-17 15:15: Investigation of human mammary stem and progenitor subpopulations from BRCA1 mutation carriers and non-carriers (Elgene Lim, The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia) 2010-02-02 16:00: Non-canonical p38 stress signaling in metabolism and inflammation (Romeo Ricci, Institute of Cell Biology, ETH Zurich) 2010-03-08 13:00: Developing network models of disease (Jonathan M.J. Derry, Director of Research, Sage Bionetworks, Seattle) 2010-04-02 14:00: Regulation of Alternative Splicing by Histone Modifications (Reini Luco, National Cancer Institute, National Institutes of Health, Bethesda) 2010-04-29 11:00: The protein atlas - a dictionary of 40% of all non-redundant human proteins (Caroline Kampf, Site Director Uppsala, Human Proteome Resource program) 2010-05-14 10:30: The patterns and temporal dynamics of genomic instability in metastatic pancreatic cancer (Peter Campbell, Wellcome Trust Sanger Institute) 2010-05-17 13:00: Modelling human colon cancer initiation and progression in the mouse (Professor Alan R. Clarke, Joint Head of Research, Cardiff School of Biosciences) 2010-06-03 15:00: Regulation of cell cycle progression by CDK-mediated substrate phosphorylation and ubiquitination (Boris Sarcevic, Unit Head, Cell Cycle and Cancer Unit, St Vincent's Institute, Victoria, Australia) 2010-06-17 11:30: New RNA-Seq protocol for Illumina sequencing (Chris Streck, Illumina) 2010-06-23 09:30: Definiens Image Analysis for Translational Research and Clinical Diagnostics (Martin Baatz, Manfred Voglmeier and Oliver Lehner - Definiens AG, Munich) 2010-06-28 13:00: Translating airway gene expression into a biomarker for lung cancer (Avi Spira, School of Medicine, Boston University) 2010-09-22 14:00: 3rd Generation Sequencing Technology (Ion Torrent) 2010-12-21 12:00: Breast MRI by the Shutter-Speed Method: Elimination of Unnecessary Breast Biopsies (Charles S. Springer Jr, Oregon Health and Science University, USA) 2011-05-19 14:30: Haloplex technology: a genome capture system for next generation sequencing (Olle Ericsson, Halo Genomics) 2011-06-02 17:00: Metabolomic Studies of Cancer Using 13C Tracer Substrates and Model Fitting (Laszlo G Boros, Associate Professor of Paediatrics, UCLA School of Medicine, and Chief Scientist, SiDMAP LLC, Los Angeles, USA) 2011-06-27 13:00: Progress towards a biomarker discovery-to-development pipeline in clinical proteomics (Michael Gillette, Broad Institute of MIT and Harvard) 2011-07-01 16:00: Learnings from kinase inhibitors for cancer therapy (Gideon Bollag (Senior Vice President of Research for Plexxikon Inc., California)) 2011-08-25 12:00: HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 Herceptin in breast cancer (Anthony Kong, Weatherall Institute of Molecular Medicine, University of Oxford) 2011-10-04 11:00: Translational Cancer Genomics Research (Affymetrix) 2011-10-04 13:00: So what is the real function of chromatin? (David Bazett-Jones: Senior Scientist, The Hospital for Sick Children, Professor, Department of Biochemistry, University of Toronto) 2011-10-11 11:00: Regulation of tumour adaptability in endocrine resistant breast cancer (Leonie Young, Royal College of Surgeons, Dublin) 2011-10-25 10:30: The use of cell lines – promises and pitfalls (Ian Freshney, Cancer Research UK Centre for Oncology and Applied Pharmacology, University of Glasgow) 2011-11-10 13:00: Drug resistance and disease progression: lessons from prostate cancer (Charles Sawyers, Memorial Sloan Kettering Cancer Centre) 2011-12-05 10:30: Novel risk biomarkers based on DNA repair for early detection and prevention of lung cancer. (Zvi Livneh, Weizmann Institute of Science) 2012-02-02 15:00: A STAT3‐induced metabolic switch involved in tumour transformation mediates STAT3 addiction (Valeria Poli, University of Turin) 2012-02-23 10:00: Cellular senescence as both a dynamic and a static phenotype (Masashi Narita, Cambridge Research Institute) 2012-02-24 09:30: Why 90% of novel anticancer agents are ineffective in clinical trial – and what to do about it (John Hickman, Coordinator, EU Innovative Medicines Initiative PREDECT, Paris) 2012-04-19 16:15: Gene expression programs controlling ER-negative breast cancer phenotype (Alex Swarbrick, Garvan Institute, Australia) 2012-04-20 15:00: The ETS transcription factor ELF5 and breast cancer phenotype (Chris Ormandy, Garvan Institute, Australia) 2012-05-03 15:00: Massively multi-parameter single cell data by Mass Cytometry: the technology of its acquisition and networks for its interpretation (Scott Tanner, University of Toronto and DVS Sciences) 2012-07-19 16:00: How mitotic spindles adapt to the presence/absence of centrosomes (Hélder Maiato, Universidade do Porto, Portugal) 2012-09-12 13:00: Niche, signaling, and epigenetic regulation of stem cells (Linheng Li, Stowers Institute for Medical Research) 2012-09-13 11:45: Functional heterogeneity in intestinal stem cells and cancer (Doug Winton, Cancer Research UK Cambridge Research Institute) 2012-12-11 10:00: Molecular pathology: building the backbone of translational research and personalised medicine (Manuel Salto-Tellez, Queens's University Belfast) 2013-01-16 11:00: Fundamentals and Applications of Mass Cytometry, using CyTOF (Jane Limer, DVS Sciences) 2013-02-26 16:00: Expansion and spread of oncogenic K-ras mutant stem cells throughout the intestinal epithelium (Hugo Snippert (Molecular Cancer Research, University Medical Center, Utrecht)) 2013-03-13 12:30: New tools for NGS libraries: Long-Span, Mate-Pair Scaffolding and Methods for Faster Library Creation (David Mead, Founder and Chief Executive Officer of Lucigen ) 2013-04-10 11:00: Standardising tumour tissue dissociation to increase the reliability and reproducibility of downstream analysis (Dawn Farrar, Miltenyi Biotec) 2013-05-16 10:30: SMARTer cDNA Synthesis for Illumina Sequencing and iDimerize Inducible Dimerization Systems (Syed Abedi, Takara-Clontech) 2013-10-04 13:00: Tumor hypoxia: developing prognostic biomarkers to predict therapeutic outcome (Ralph P. Mason, The University of Texas Southwestern Medical Center) 2013-12-09 13:00: Comprehensive transcriptome and epigenome sequencing of hypoxic breast cancer reveals non-coding RNAs associated with clinicopathological features (Ioannis (Jiannis) Ragoussis, McGill University, Canada and Genome Quebec Innovation Centre) 2013-12-13 13:00: Detecting low-concentration compounds with water sensitivity and spectroscopic specificity using CEST-MRI (Peter van Zijl, Johns Hopkins University and Kennedy Krieger Institute) 2014-03-19 13:00: Targeted Cancer Therapy: Accomplishments and Challenges (John Mendelsohn, MD Anderson Cancer Center Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy) 2014-03-19 15:00: **CANCELLED** The role of EGFR family receptor signaling-induced NF-kB activation in human breast cancer (Debajit Biswas, Dana-Farber Cancer Institute and Harvard Medical School) 2015-04-22 13:00: Role of Extracellular Metabolites in Tumor Organization (Dr Carlos Carmona-Fontaine (Memorial Sloan Kettering Cancer Center)) 2016-04-12 15:00: Charting the human centrosome-cilium landscape (Dr Laurence Pelletier, Lunenfeld-Tanenbaum’s Institute)