MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY 2022-10-05 15:00: POSTPONED - Cdk12 maintains the axon initial segment through actin remodelling (Dr Gaynor Smith | Cardiff University) 2022-10-11 15:00: Identifying the network of bactericidal interactions between mycobacterial respiratory chain complexes to develop fast-acting drugs for tuberculosis (Professor Gregory M. Cook, University of Otago, New Zealand) 2022-10-31 15:00: The Parkinson’s disease protein LRRK2 regulates the transition from innate to adaptive immunity by modulating the unfolded protein response (Professor Michel Desjardins, University of Montreal) 2022-11-16 15:00: Dual transport function of mitochondrial uncoupling proteins (Professor Elena Pohl | University of Veterinary Medicine, Vienna ) 2022-11-23 15:00: Rescuing mitochondria in peril under oxidative stress (Professor Kostas Tokatlidis | University of Glasgow) 2022-11-24 15:00: How is mtDNA transcription regulated? (Professor Nils-Göran Larsson, Karolinska Institute ) 2022-12-07 15:00: Patterns underlying the mitochondrial life cycle (Professor Sulina Manley, Laboratory of Experimental Biophysics - EPFL ) 2023-02-15 15:00: The Wonders of Small Molecule Transport (Professor David Drew | Stockholm University ) 2023-03-01 15:00: ER stress and mitochondria  (Professor Giovanna Mallucci | Founding Principal Investigator, Altos Labs Cambridge Institute of Science, Cambridge UK) 2023-04-05 15:00: Remodeling of Mitochondria during Microbial Infection (Dr Lena Pernas | MPI, Cologne) 2023-04-25 15:00: Curbing mitochondrial dysfunction in neurodegeneration: lessons from neurogenetics (Dr Derek Narendra | National Institute of Neurological Disorders and Stroke) 2023-05-03 15:00: Subcellular renovation: shaping of the mitochondrial inner-membrane (Professor Luke Chao | Havard Medical School) 2023-05-10 15:00: Signal Switches at the Mitochondrial Import Machinery (Professor Chris Meisinger | Institute for Biochemistry and Molecular Biology, University of Freiburg) 2023-06-28 15:00: Unbiased Genetic Screening to find Modifiers of Mitochondria in Neurons (Dr Gaynor Smith | Cardiff Univeristy) 2023-09-13 15:00: From Bench to Patients; Decanoic/Octanoic Acid & Brain Energy Metabolism (Professor Simon Heales | University College London ) 2023-10-04 15:00: Selective autophagy as a mechanism of oxidative stress response (Dr Viktor Korolchuk | Faculty of Medical Sciences, Newcastle University) 2023-10-18 15:00: Mitochondrial fusion in neural stem cell differentiation in Drosophila development (Professor Richa Rikhy, Indian Institute of Science Education and Research (IISER), Pune, India) 2023-11-01 15:00: Biological energy transduction in action - deciphering the molecular mechanism of the remarkable Complex I (Professor Ville Kaila | Stockholm University) 2023-11-14 15:00: The (in)fidelity of human mitochondrial gene expression (Professor Brendan Battersby, University of Helsinki, Finland) 2023-11-15 15:00: Focusing on mitochondria with super-resolution microscopy (Professor Stefan Jakobs | Max Planck Institute, Germany) 2023-12-13 15:00: Mitochondria dynamics and metabolism regulate species-specific features of human brain development (Professor Pierre Vanderhaeghen | VIB-KU Leuven Center for Brain & Disease Research, Belgium) 2024-02-07 15:00: Unravelling the impact of membrane transporters in cancer drug uptake and efficacy (Dr Louise Fets MRC Investigator CRUK Career Establishment Awardee Drug Transport and Tumour Metabolism Lab Medical Research Council Laboratory of Medical Sciences (LMS)) 2024-03-20 15:00: Targeting liver mitochondria to treat MASLD/MASH and cardiometabolic disease (Professor Gerald Shulman) 2024-04-10 15:00: The ins and outs of mitochondrial protein quality control (Professor Dr Christian Münch) 2024-05-08 15:00: Non-uniform regulation of epigenetic marks via metabolism in a developing tissue (Professor Dr Aurelio Teleman) 2024-06-05 15:00: Drug discovery of neurological mitochondrial diseases with patient-specific brain organoids (Professor Dr. Alessandro Prigione) 2024-11-13 15:00: Mitochondrial DNA mutations in cancer – passive bystanders or active participants? (Professor Laura Greaves, University of Newcastle) 2024-12-05 15:00: Molecular determinants of inhibition of the Mitochondrial Uncoupling Protein 1­mediated respiratory uncoupling (Dr Bruno Miroux) 2024-12-11 15:00: Neurogenesis Under Stress (Dr Alex Gould) 2025-04-16 15:00: Proline metabolism and the tumour microenvironment – essential lessons from a non-essential amino acid (Professor Daniel Tennant, University of Birmingham, UK) 2025-06-18 15:00: Metabolic control of myeloid cell function (Professor David Sancho Madrid, Spanish Center for Cardiovascular Research) 2025-09-24 15:00: The role of mitochondrial transcriptional processes in modulating human health and disease (Dr Alan Hodgkinson, King's College London) 2025-10-01 15:00: The sex and geometry of inter-organ communication (Professor Irene Miguel-Aliaga, The Francis Crick Institute) 2025-11-12 15:00: Quantity and Quality: Mechanisms of Mitochondrial DNA Copy Number and Integrity Control in Saccharomyces cerevisiae (Professor Dr Christof Osman, Biocenter of the LMU, Germany) 2025-12-03 15:00: Keeping mitochondria in shape: a matter of life and death (Professor Luca Scorrano, University of Padua)