ac313's list


2008-10-17 17:00: Modern Medicinal Chemistry in the Hit to Lead Arena (Dr Dafydd Owen (Pfizer Global Research & Development, Sandwich, UK))

2008-11-03 17:00: Search for New Antibacterials Using Diversity-Oriented Synthesis (Dr David Spring (University of Cambridge))

2008-11-10 17:00: Progress Toward a Synthesis of Phomactin A (Professor Richard Hsung (University of Wisconsin, Madison, USA))

2008-11-17 17:00: Epoxide-Opening Cascades (Professor Tim Jamison (Massachusetts Institute of Technology, USA))

2008-11-24 17:00: Biomimetic Organocatalysis: From Concepts to Applications (Professor Magnus Rueping (University of Frankfurt, Germany))

2008-12-08 17:00: Designing screens and screening designs: from catalytic antibodies to peptide dendrimer enzyme models (Jean-Louis Reymond (University of Berne))

2008-12-15 17:00: Finding the Needle in a Haystack and From Bathtubs to Pipes (Dr David Ager (DSM, Raleigh-Durham, USA))

2009-04-03 16:00: Amino Acid Promoted Ullman Reactions and their Applications in Organic Synthesis (Professor Dawei Ma, Shanghai Institute of Organic Chemistry)

2009-04-15 17:00: Asymmetric Synthesis of Nitrogen Heterocycles using Sulfinimines (Professor Franklin Davis, Temple University, Philadelphia USA)

2009-04-20 13:00: SCI Graduate Symposium (SCI Graduate Symposium speakers to be confirmed)

2009-04-27 17:00: Sugars and Enzymes (Professor Ben Davis, University of Oxford)

2009-04-28 16:15: Sustainability Through the Confluence of Heterogeneous and Homogeneous Catalysis (Sir John Meurig Thomas, University of Cambridge)

2009-05-11 17:00: Merck Lectureship Talk 1 - Seeing the Light With Polymers (Professor Andrew Holmes, Bio21 Institute & CSIRO Mol & Health Tech, University of Melbourne, Australia)

2009-05-13 17:00: Merck Lectureship Talk 2 - Pericyclic Reactions in the Synthesis of Medium Ring Ether and Piperidine Alkaloids of Biological Importance (Professor Andrew Holmes, Bio21 Institute & CSIRO Mol & Health Tech, University of Melbourne, Australia)

2009-05-15 17:00: Merck Lectureship Talk 3 - Probing Intracellular Signalling Processes with Phosphatidyl Inositol Polyphosphates . (Professor Andrew Holmes, Bio21 Institute & CSIRO Mol & Health Tech, University of Melbourne, Australia)

2009-06-01 17:00: Synthesis of Bridged Natural Products (Speaker to be confirmed)

2009-06-22 17:00: "Mechanisms, Structures and Chemical Informatics" (Dr Jonathan Goodman, University of Cambridge)

2009-07-03 17:00: Chiral Proton Catalysis: The Development of New Reactions and Reagents for Alkaloid Synthesis (Professor Jeff Johnston, Vanderbilt University)

2009-07-22 11:00: Synthetic Peptides for DNA and Protein recognition (Professor Jose-Luis Mascarenas, University of Santiago de Compostela)

2009-08-03 17:00: Recent advances in the area of asymmetric hydrogenation (Professor Xumu Zhang, Rutgers University, USA)

2009-08-13 17:00: Opportunities and Lessons in Chemistry and Biology Stemming from an Investment in Total Synthesis (Professor Andrew Phillips, University of Colorado)

2009-09-24 17:00: Atom Economic Transformations Catalysed by Low-Valent Cobalt Complexes (Professor Gerhard Hilt (Marburg University))

2009-10-19 17:00: Sorting the Wheat from the Chaff - Route Selection using Kepner-Tregoe Decision Analysis (Dr Jeremy Parker from Astra Zeneca)

2009-10-26 13:00: Graduate Symposium plus Successful Drug Discovery and Development at Pfizer: Thanks to Organic Synthesis (Dr Dafydd Owen from Pfizer)

2009-11-02 17:00: Design of chiral ligands for asymmetric copper-catalyzed reactions (Professor Alex Alexakis, University of Geneva)

2009-11-09 17:00: Adventures in conjugate addition chemistry: from alkene hydroacylation to protein bioconjugation (Professor Steve Caddick, UCL)

2009-11-16 17:00: Metallonitrene/Alkyne Metathesis and Beyond:  Transition Metal Catalyzed Oxidative Amination for Organic Synthesis (Professor Simon Blakey, Emory University, USA)

2009-11-23 17:00: New Genetic Codes (Dr Jason Chin, University of Cambridge, MRC-LMB)

2009-11-30 17:00: New Strategies for the Synthesis of Glycopeptides and Glycoproteins (Dr Richard Payne, University of Sydney)

2010-01-13 17:00: New Catalysis Concepts (Professor David W. C. MacMillan,  Princeton University, USA)

2010-01-25 17:00: Development of New Methods for Catalytic C–H Functionalization: Critical Interplay between Catalyst Design and Mechanistic Analysis (Professor Melanie Sanford, University of Mighigan, USA)

2010-02-22 17:00: Sequencing genomes and sequences in the genome: from chemistry to medicine (Professor Shankar Balasubramanian, University of Cambridge)

2010-03-01 17:00: Chiral Carbenoids for Asymmetric Synthesis (Professor Varinder Aggarwal, University of Bristol)

2010-03-25 17:00: Structural biology of small RNA-mediated gene regulation and methylation-mark mediated epigenetic regulation (Dr, Dinshaw J. Patel, Memorial Sloan-Kettering Cancer Center, New York)

2010-04-19 17:00: CANCELLED DUE TO AIR TRAVEL PROBLEMS (Emily Parker)

2010-04-23 11:00: Joe Spencer Memorial Lectures (11.00  Prof Peter Leadley (Cambridge), 11.45 Dr Joseph Wright (UEA), 12.15 Dr Dieter Spiteller (MPI Jena), 1.45 Prof Timor Baasov (Technion, Isreal), 2.30 Dr Andrew Truman (Cambridge), 3.00 Prof David O'Hagan (St Andrews), 4.15 Prof Jin-Quan Yu (Scripps))

2010-04-30 17:00: Shedding Light on the Biosynthesis of Cyanobacterial Sunscreens (Dr Emily Balskus, Harvard Medical School)

2010-05-10 17:00: Multicomponent approaches to organic synthesis and chemical biology (Jared Shaw)

2010-05-10 17:00: CANCELLED (Juan Granja)

2010-05-24 17:00: Exploring the evolutionary relationships and the reaction chemistry in a family of crucial biosynthetic aldolases ( Professor Emily J Parker, University of Canterbury - Christchurch, New Zealand)

2010-10-01 16:15: Small Molecules and Light as Tools for the Regulation of Biological Processes (Professor Alex Dieter North Carolina State University)

2010-10-06 10:30: Membrane activation of the adaptor complex AP2 in clathrin-mediated endocytosis (Dr. Phil Evans MRC Laboratory of Molecular Biology)

2010-10-07 14:00: New Supramolecular Strategies in Transition Metal Catalysis (Professor Joost Reek, Van t Hoff Institute for Molecular Sciences, Amsterdam.)

2010-10-13 10:30: From conformational chaos to robust regulation: the structure and function of a multi-enzyme machine from RNA metabolism ( Prof. Ben Luisi  Department of Biochemistry, University of Cambridge)

2010-10-20 10:30: Molecular Biological and Molecular Genetic studies of the Mechanisms Underlying  Neurodegeneration in Alzheimer's Disease (Prof. Peter Hyslop  Cambridge Institute for Medical Research)

2010-10-27 10:30: Skeletal diversity in sesquiterpenes from the perspective of a cyclizing carbocation (Dr. Paul O'maille  John Innes centre, Norwich, UK)

2010-11-01 13:00: Pfizer Graduate Symposium and talk (Dr Daffydd Owen, Pfizer Global Research & Development,)

2010-11-03 10:30: Host matrix-pathogen interactions and redox sensing; tandem beta-zippers and "inside-out" protein-protein recognition. ( Dr. Jennifer Potts  University of York)

2010-11-08 14:00: No Strain, No Gain?: Lessons in Catalysis (Professor Mark Lautens, University of Toronto)

2010-11-10 10:30: Aminoacyl-tRNA synthetases:  Possible Origins and Molecular Mechanisms Leading to the  Evolution of Enhanced Catalytic Activity, Specificity, and Allostery (Dr. Charles Carter  University of North Carolina, NC, USA)

2010-11-15 17:00: The Discovery of Orally Bioavailable CGRP Receptor Antagonists: From Concept to Clinical Efficacy (Dr Ian Bell, Merck, USA)

2010-11-17 10:30: From coarse-grained models of fibril formation to atomistic details of potential inhibitors (Prof. Amedeo Caflisch  Department of Biochemistry, the University of Zurich, Zurich, Switzerland)

2010-11-24 10:30: Designing protein polymerases for unnatural nucleic acids (Vitor Pinheiro  MRC Laboratory of Molecular Biology)

2010-11-29 14:00: Metallopolyynes and Metallophosphors: Multifunctional Materials with Emerging Applications in Optical Devices RSC Chemistry of the Transition Metals Award Lecture 2010 (Professor Raymond Wong, RSC award lecture)

2010-12-01 10:30: Structural Ensembles of Small Peptides - An NMR Perspective (Dr. Stephan Schwarzinger  Institute of Biopolymers, University of Bayreuth, Germany)

2010-12-01 17:00: CANCELLED (Professor Mike Krische, University of Texas)

2011-01-26 10:30: Title to be confirmed (Dr. Robert Best, University of Cambridge.)

2011-02-02 10:30: Title to be confirmed (Andras Malnasi-Csizmadia, Department of Biochemistry Eötvös University, Budapest)

2011-02-09 10:30: Structural insights into the initiation of DNA synthesis in eukaryotic replication (Dr. Luca Pellegrini, Department of BIochemistry, University of Cambridge)

2011-02-14 10:30: Title to be confirmed (Andreas Ramos, NIMR, London)

2011-02-16 10:30: Applications of single molecule fluorescence to  biology (Prof. David Klenerman, Department of Chemistry, University of Cambridge)

2011-02-23 10:30: Title to be confirmed (Fabio Falsone, University of Graz, Austria)

2011-03-02 10:30: Quality control in the IgM factory: the many roles of ERp44 (Roberto Sitia, San Raffaele Hospital, MILAN)

2011-03-09 10:30: TBC (Nobu Tokuriki, Department of Chemistry, University of Cambridge.)

2011-03-16 10:30: Modular protein-nucleic acid interactions in the FBP family (Andres Ramos, NIMR MRC)

2011-03-22 10:30: Creating novel proteins by selection and design (Lynne Regan, Yale University)

2011-04-08 01:00:  Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity ( Abel Garcia-Pino,University of Brussels, Belgium)

2011-05-09 14:00: RSC Organic Symposium at the University of Cambridge (Professor Kevin Booker-Milburn University of Bristol  - Dr Matthew Clarke University of St Andrews - Professor Dieter Enders RWTH-Aachen)

2011-06-01 10:30: Manipulating protein aggregation in the nervous system (Prof Michael Cheetham, Division of Molecular and Cellular Neuroscience, UCL)

2011-06-08 10:30: Key macromolecules in bacterial infections: a structural perspective (Dr. Rita Berisio, Institute of Biostructures and Bioimaging, Italian National Research Council.)

2011-07-07 15:30: Molecular Simulations in Structure-Based Drug Design (Dr Julien Michel, Royal Society University Research Fellow, School of Chemistry, University of Edinburgh)

2011-10-12 14:15: Conformational dynamics of single protein molecules under load (Prof. Matthias Rief, Technische Universität München)

2011-10-21 14:00: Title to be confirmed (Professor Bill Rutherford, CEA, France)

2011-11-09 14:15: Linnett Lecture: "The Theory of the Structural Glass Transition" (Prof. Peter Wolynes, Rice University)

2011-11-18 14:00: Sialidases in respiratory disease (Prof Garry Taylor FRSE, Head of the School of Biology, BSRC, University of St Andrews)

2011-11-22 16:50: 'The Chemistry of Genome Maintenance' (Professor Thomas Carell -Chemical Science Lecturer)

2011-11-25 14:00: Expanding the central dogma (Professor Philipp Holliger, MRC Laboratory of Molecular Biology)

2012-01-09 17:00: Mechanisms matter: understanding and optimizing drugs for the treatment of tuberculosis (Dr Clifton E. Barry III, Tuberculosis Research Section, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD)

2012-01-18 17:00: Small Molecule Control of Intracellular Protein Levels (Prof. Craig M. Crews, Dept. of Molecular, Cellular, Developmental Biology, Dept. of Pharmacology & Dept. of Chemistry, Yale University)

2012-01-27 14:00: Exploiting Cryptic Biosynthetic Pathways in Microorganisms (Prof. Dr. Christian Hertweck, Leibniz Institute for Natural Product Research and Infection Biology, HKI, Jena, Germany)

2012-02-03 14:00: From Fragments and Hot-Spots to Novel Lead Structures (Professor Dr Gerhard Klebe, Institute of Pharmaceutical Chemistry, Philipps-University Marburg)

2012-02-23 17:00: Title to be confirmed (Dr G Marius Clore, National Institutes of Health, USA)

2012-03-02 14:00: Future perspectives of metal compounds in cancer therapy (Professor Bernhard Keppler, University of Vienna)

2012-03-09 14:00: Predicting protein-peptide and protein-chemical interactions using biological networks (Robert B. Russell, Professor Protein Evolution, CellNetworks, University of Heidelberg, Germany)

2012-03-12 17:00: 'Chemistry of Oxygen Sensing in Animals' (Prof. Christopher Schofield, Department of Chemistry, University of Oxford)

2012-03-30 14:00: Catalytic MetalloDrugs – New Therapies for Old Problems (Professor James Cowan, Ohio State University)

2012-04-30 17:00: Mechanistic and structural studies on thiamin biosynthetic enzymes (Professor Tadgh P. Begley, D. H. R. Barton and Robert A. Welch Chair in Chemistry, Texas A&M University)

2012-05-11 14:00: New Protein Structures and Assemblies by Rational Design (Dek Woolfson, Professor of Chemistry & Biochemistry, School of Chemistry, University of Bristol)

2012-05-16 10:30: New Insights into Proteasome Function: From Protein Degradation to Cancer Therapy (Alfred Lewis Goldberg, Professor of Cell Biology, Harvard Medical School)

2012-05-18 13:00: "Molecular mechanisms of O-GlcNAc signalling" (Professor Daan van Aalten, FRSE, Associate Dean, Division of Molecular Microbiology, College of Life Sciences, University of Dundee)

2012-06-06 17:00: "Molecular Behaviour in Small Spaces" (Professor Julius Rebek, Jr., Ph.D - Director, Skaggs Institute for Chemical Biology)

2012-11-16 11:00: "Py-Im Polyamides – from DNA Recognition to In Vivo Experiments" (Dr Jevgenij A. Raskatov, California Institute of Technology)

2013-01-14 16:00: Allostery and Conformational Control in Signaling: The Ubiquitin E3 Ligases (Dr Ruth Nussinov. Professor, Department of Human Genetics, School of Medicine, Tel Aviv University, Israel Senior Principal Scientist and Principal Investigator at the National Cancer Institute (NCI), Frederick, MD)

2013-03-04 16:00: Selective targeting of epigenetic effector domains of the bromodomain family (Professor Stefan Knapp, Structural Genomics Consortium, University of Oxford)

2013-08-12 14:00: "Porous Organic Cages - A Serious Alternative to Extended Framework Materials" (Professor Michael Mastalerz, Ruprecht-Karls-University of Heidelberg)

2014-01-06 14:00: Mitochondria-targeted Delivery Systems (Dr Shanta Dhar, Department of Chemistry, University of Georgia)

2014-11-19 16:00: Boron based dynamic bonding: an emerging construction tool for Chemical Biology (Professor Pedro Gois, Lisbon University)

2015-03-18 16:00: TBC (Prof. Edward Tate, Imperial College)

2015-04-28 16:00: Exploitation of fundamental and biomedical functions of clathrin-independent endocytosis (Prof. Ludger Johannes, Institute Curie)

2015-06-08 16:00: Mechanisms of microbial elemental sulfur reduction at the community, cellular and enzymatic levels (Professor E J Crane (III), Pomona College, Claremont, California)

2015-09-16 14:00: Mass Spectrometry in Structural Biology (Dr Dijana Matak-Vinkovic, University of Cambridge)

2015-10-14 16:00: Rapid Identification of cyclic peptide inhibitors of protein-protein interactions (Prof. Ali Tavassoli, University of Southampton)

2015-10-28 16:00: Sugars and Proteins (Professor Ben Davis ( University of Oxford))

2015-11-25 16:00: Uncovering the mechanisms of Protein O-Glycosylation (Dr Ramon Hurtado-Guerrero, University of Zaragoza)

2015-12-09 16:00: The nature of chemistry publishing (Dr Stuart Cantrill, Chief Editor of Nature Chemistry)

2016-01-13 16:00: This talk has been postponed (Marc Robillard, CEO of TagWorks)

2016-05-18 16:00: Reprogramming the Genetic Code (Dr Jason Chin,  Centre for Chemical & Synthetic Biology, MRC Laboratory of Molecular Biology)

2016-10-05 16:00: Computers helping chemists: a toolkit for a ChemBio lab (Gonzalo JIMÉNEZ-OSÉS, University of La Rioja)

2017-03-15 16:00: Studies on the Molecular Recognition of aminoglycoside antibiotics by nucleic acids and proteins (Juan Luis Asensio, Instituto de Química Orgánica General, Madrid)

2017-04-19 16:00: Design and use of chemical tools to modulate gene expression in cancer cells based on the targeting of DNA methyltransferase (Paola B. Arimondo, CNRS Pierre Fabre Laboratories, Toulouse France Overseas Fellow Churchill College, Cambridge)

2017-04-21 13:00: Enzyme Catalysis, Inhibition & Resistance: A Design Perspective (Professor Bruce Tidor, MIT)

2017-07-13 12:00: Sulfur Chemistry for Biology and the Environment (Dr Justin Chalker)

2017-07-14 14:00: Rational Metallodrug Development: Novel Pharmacophores and Mode of Action Investigations (Christian G Hartinger, University of Auckland, New Zealand)

2017-09-03 16:00: Protein Folding, Evolution and Interactions Symposium (Keynote Speakers: Professor Sir Alan Fersht and Professor Dame Carol Robinson)

2017-09-04 09:00: Protein Folding, Evolution and Interactions Symposium (Keynote Speakers: Professor Sir Alan Fersht and Professor Dame Carol Robinson)

2017-09-05 09:00: Protein Folding, Evolution and Interactions Symposium (Keynote Speakers: Professor Sir Alan Fersht and Professor Dame Carol Robinson)

2017-09-14 14:00: Learning and Applying Nature's Biosynthetic Logic (Prof. Bradley S. Moore, Scripps Institution of Oceanography, San Diego)

2018-01-16 16:00: Improving the Prediction of In vivo Drug Activity (Peter Tonge, Institute for Chemical Biology & Drug Discovery, Stony Brook University USA)

2018-05-22 16:00: Multicomponent Reactions in Peptide and Protein Chemistry   (Prof Daniel García Rivera from the Faculty of Chemistry, University of Havana (Cuba))

2019-02-26 16:00: A chemical biology approach to the modulation of cell fate and cell state  (Dr Luke Lairson, Scripps)

2019-03-12 16:00: Establishing meso-methyl BODIPYs as viable visible-light excitable photocages (Roy Weinstain - Tel-Aviv University)

2019-03-26 16:00: The nature of chemistry publishing (Dr Stuart Cantrill, Chief Editor Nature Chemistry)

2019-03-27 16:00: Modified nucleosides, nucleotides and nucleic acids for medicinal chemistry and chemical biology (Prof Michal Hocek - IOCB Prague - Czech Republic)

2019-04-05 11:00: Diversity Oriented Biosynthesis: Making Complex Cyclic Peptides Using a Combination of Synthesis and Enzymes (Prof. Marcel Jaspars (Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen))

2019-04-23 16:00: Coordination-Assisted Bioorthogonal Chemistry: Bringing Orthogonality in the Tetrazine Ligation with (strained) alkenes (Kimberly M. Bonger)

2019-06-10 16:00: NEW drugs from OLD pathways - Teaching Nature New Tricks (Professor Tom Simpson, University of Bristol)

2019-10-09 14:30: Rapid discovery and chemical synthesis of proteins (Professor Bradley Pentelute, MIT Department of Chemistry)

2019-11-06 16:00: Fluorescent Nucleoside Analogues with New Properties for Biophysics (Byron W Purse San Diego State University)

2020-02-25 16:00: Title to be confirmed (Dr Matthew Powner, University College London)

2020-03-25 16:00: Title to be confirmed (Professor Nigel Scrutton, The University of Manchester)

2022-05-10 15:00: Metal Complexes as Diagnostics and Therapeutics (Prof. Gilles Gasser, Chimie ParisTech)

2022-10-25 16:00: NAD as a building block in natural product biosynthesis (Dr Takayoshi Awakawa, University of Tokyo)

2022-11-17 14:00: Supramolecular Peptide Assemblies For Functional Systems (Javier Montenegro, Santiago de Compostela University)

2023-02-27 16:00: Discovery of cyclotides and their applications in peptide-based drug design (Professor David Craik (Institute for Molecular Bioscience, The University of Queensland))

2023-03-20 14:00: Synthetic biology approaches to new chemistry (Michelle C. Chang, University of California, Berkeley)

2023-05-24 14:00: Lessons from Collagen (Professor Ronald T. Raines, MIT)

2023-06-23 14:00: New Technologies for the Synthesis, Semi-Synthesis and Biosynthesis of Modified Peptides and Proteins (Professor Richard J. Payne, University of Sydney)

2023-11-29 15:00: Sugars & proteins (Benjamin G. Davis The Rosalind Franklin Institute and University of Oxford)

2023-12-05 14:00: Tools and Tactics for Targeting RNA with Small Molecules (John 'Jay' Schneekloth, Jr., Ph.D. from NIH/NCI)

2023-12-07 16:00: Designing enzymes from scratch (Professor Donald Hilvert, (ETH) Zürich)

2024-04-08 14:00: Antibodies by design: from drug development to brain drug delivery (Prof Peter M. Tessier, University of Michigan)

2025-03-31 15:00: DNA-Encoded Chemical Libraries - A BIOLOGICAL RIG SEMINAR (Professor Dario Neri - CEO and CSO of Philogen, Professor of ETH Zürich, Honorary Senior Visiting Fellow, Department of Radiology, University of Cambridge (UK))

2025-04-01 14:30: The Druggable Transcriptome Project: From Chemical Probes to Precision Medicines   (Matthew Disney - Scripps Research Institute)

2025-04-08 15:00: Recent aspects of chaperone functions in health and disease - A BIOLOGICAL RIG SEMINAR (Prof. Ulrich Hartl - Max-Planck-Institute of Biochemistry)

2025-09-25 14:00: The Many Guises of Reactive Metabolite Signalling (Prof. Yimon Aye - Chemical Biology at the University of Oxford)

2026-02-06 15:00: De Novo Design of Functional Proteins (William DeGrado, University of California, San Francisco)