Sackler Lecture Theatre, Level 7, CIMR, Cambridge Biomedical Campus 2015-01-22 12:00: Lessons from murine norovirus (Dr Christiane Wobus, Department of Microbiology and Immunology, University of Michigan Medical School, USA) 2015-02-05 12:00: Poxvirus Entry and Uncoating (Dr Jason Mercer, MRC Laboratory for Molecular Cell Biology, University College London, UK) 2015-02-19 12:00: The DNA repair machinery; more than just repairing DNA (Dr Brian Ferguson, Department of Pathology, University of Cambridge, UK) 2015-03-05 12:00: What we can learn from the structure of viral RNA-dependent RNA polymerase complexes (Dr Núria Verdaguer, Molecular Biology Institute of Barcelona, CSIC, Spain) 2015-03-19 12:00: Novel proteins encoded by genomes of vector-borne dsRNA viruses and their involvement in innate immune modulation both in the arthropod vector and mammalian host (Dr Houssam Attoui, Arbovirus Molecular Research Group, The Pribright Institute, UK) 2015-04-16 12:00: To sense or not to sense viral RNA - essentials of coronavirus innate immune evasion (Prof. Volker Thiel, Institute of Virology and Immunology, University of Bern, Switzerland) 2015-04-30 12:00: The APOBEC antiviral response, HPV and Cancer (Dr Tim Fenton, UCL Cancer Institute, University College London, UK) 2015-05-07 12:00: Structural and functional insights into RNA polymerases from –ve sense RNA viruses (Dr Jonathan Grimes, Nuffield Department of Medicine, University of Oxford, UK) 2015-05-14 12:00: Trim28 and KRAB-zinc finger proteins silence retrotransposons and cellular genes (Dr Helen Rowe, Division of Infection & Immunity, University College London, UK) 2015-05-21 12:00: Host cell ion channels as new anti-viral targets? (Dr Jamel Mankouri, School of Molecular and Cellular Biology, University of Leeds, UK) 2015-10-08 12:00: Lessons in viral pathogenesis from the barnyard (Prof. Massimo Palmarini, Centre for Virus Research, MRC / University of Glasgow, UK) 2015-10-15 12:00: Veni, vidi, virion: new conquests of hepatitis C virus (Dr Brett Lindenbach, Department of Microbial Pathogenesis, Yale School of Medicine, USA) 2015-10-22 12:00: Role of ISG15 in poxvirus infection in macrophages (Dr Susana Guerra, Department of Preventive Medicine and Public Health and Microbiology, Universidad Autónoma, Madrid, Spain) 2015-10-29 12:00: Human Papillomaviruses: From Infectious Entry to Malignancy (Dr Lawrence Banks, Tumour Virology Group, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy) 2015-11-26 12:00: New insights into HIV replication and spread in T cells (Dr Clare Jolly, Division of Infection & Immunity, University College London, UK) 2016-01-21 12:00: Why do insects vary genetically in susceptibility to viral infection? (Dr Frank Jiggins, Department of Genetics, University of Cambridge, UK) 2016-02-04 12:00: The long road to global polio eradication (Dr Javier Martin, Division of Virology, National Institute for Biological Standards and Control, UK) 2016-02-18 12:00: Antigenicity of the HPV major capsid protein (Dr Simon Beddows, Virus Reference Department, Public Health England, UK) 2016-03-03 12:00: Domestication, imperialism and the emergence of pandemic retroviral infection in small ruminants (Dr Robert Gifford, Centre for Virus Research, MRC / University of Glasgow, UK) 2016-03-17 12:00: Flavivirus sensing and signalling (Dr Nolwenn Jouvenet, Department of Virology, Viral Genomics and Vaccination, Pasteur Institute, France) 2016-04-21 12:00: Interferons, paramyxoviruses and host cell interactions: molecular mechanisms and biological consequences (Prof. Rick Randall, School of Biology, University of St. Andrews, UK) 2016-05-12 12:00: Pre-emptive vaccine updates and immunity management: A new strategy for vaccinating against influenza viruses (Prof. Derek Smith, Department of Zoology, University of Cambridge, UK) 2016-05-19 12:00: Host determinants of HTLV-1 integration (Dr Goedele Maertens, Department of Medicine, Imperial College London, UK) 2016-05-26 12:00: Noncytotoxic immune control of cytomegalovirus by killer cell proteases (Dr Neils Bovenschen, Department of Pathology, University Medical Center Utrecht, Netherlands) 2016-06-02 12:00: The Nidovirus Connection: from Arteriviruses to MERS-coronavirus, and back (Prof. Eric Snijder, Department of Medical Microbiology, Leiden University Medical Center, Netherlands) 2016-06-16 12:00: HIV-1 restriction by SAMHD1 (Dr Kate Bishop, The Francis Crick Institute, UK) 2016-10-06 12:00: Vaccinia virus induces a cytoplasmic DNA damage response to facilitate replication (Dr Antonio Postigo, The Francis Crick Institute, London, UK) 2016-10-20 12:00: Kaposi’s sarcoma herpesvirus as a valuable model system for cancer biology research (Prof. Päivi Ojala, Division of Infectious Diseases, Imperial College London, UK) 2016-10-27 12:00: Structural insights into how picornaviruses infect cells and how we might stop them (Prof. David Stuart, Division of Structural Biology, University of Oxford, UK) 2016-11-10 12:00: Genetic and Proteomic Approaches to Viral Evasion (Prof. Paul Lehner, Cambridge Institute for Medical Research, University of Cambridge, UK) 2016-12-01 12:00: The long journey of hepatitis C virus entry into hepatocytes (Dr Jean Dubuisson, Center for Infection & Immunity of Lille, Université de Lille, France) 2017-01-26 12:00: Antibody Responses in Dengue and Zika Infection (Prof. Gavin Screaton, Imperial College London, UK) 2017-02-09 12:00: Papillomavirus sabotage of epithelial growth and differentiation pathways: New targets for intervention? (Dr Andrew Macdonald, University of Leeds, UK) 2017-02-16 12:00: Host cell/virus interactions in the late stages of the HIV life cycle (Prof. Andrew Lever, Univeristy of Cambridge) 2017-03-02 12:00: Studying virus infection in cells with new imaging techniques (Dr Cristina Risco, Centro Nacional de Biotecnologia, Madrid, Spain) 2017-03-16 12:00: Deregulation of long-range gene control in lymphoma: insights from Epstein-Barr virus (Prof. Michelle West, University of Sussex, UK) 2017-03-30 12:00: Alphavirus induced inflammatory disease: new insights into disease mechanisms and therapeutic approaches (Prof. Suresh Mahalingam, Griffith University, Queensland, Australia) 2017-04-27 12:00: Towards understanding the molecular mechanism(s) of IFITM-mediated restriction of viral entry (Prof. Mark Marsh, MRC Laboratory for Molecular Cell Biology, University College London, UK) 2017-05-11 12:00: The role of the host and co-infections in Ebola virus disease and its outcome (Prof. Julian Hiscox, University of Liverpool, UK) 2017-05-25 12:00: Cryomicroscopy of viruses, from atomic-resolution structure to in situ 3D imaging (Dr David Bhella, University of Glasgow, UK) 2017-06-08 12:00: Hepatitis B virus cccDNA regulation and spatial nuclear organization (Dr Christine Neuveut, Institut Pasteur, France) 2017-09-04 12:00: Novel insights into HIV assembly and maturation (Dr Eric O. Freed, National Cancer Institute, NIH - Frederick, MD, USA) 2017-10-05 12:00: Studying the structure and assembly of HIV-1 and other enveloped viruses using cryo-electron tomography (Dr John Briggs, MRC Laboratory of Molecular Biology, Cambridge) 2017-10-19 12:00: The importins of Herpes Simplex Virus nuclear targeting (Prof. Beate Sodeik, Hannover Medical School, Hannover, Germany) 2017-11-02 12:00: What does endogenising a retrovirus do to its host, the example of koala retrovirus? (Dr Rachel Tarlington, School of Veterinary Medicine and Science, University of Nottingham, UK) 2017-11-09 12:00: The trials and tribulations of using field deployable genomics during epidemic response (Prof. Ian Goodfellow, University of Cambridge) 2017-11-23 12:00: Cellular and molecular mechanisms of arbovirus pathogenesis: implications for therapeutic interventions (Lisa Fong Poh NG, Agency for Science, Technology and Research, Singapore) 2017-11-30 12:00: A novel innate immune antagonist function in influenza A virus? (Prof. Paul Digard, The Roslin Institute, University of Edinburgh, UK) 2018-01-18 12:00: Potato mop-top virus co-opts the HIPP26 drought stress sensor for long distance movement (Lesley Torrance, University of St Andrews, UK) 2018-02-01 12:00: Life on the edge of equilibrium: The roles of asymmetric components in ssRNA viruses (Peter Stockley, University of Leeds) 2018-02-15 12:00: Two transmissible cancers in Tasmanian devils (Elizabeth Murchinson, Department of Veterinary Medicine, University of Cambridge) 2018-03-01 12:00: Emerging Human coronavirus virulence and protection (Luis Enjuanes, Spanish National Centre for Biotechnology, Madrid, Spain) 2018-03-15 12:00: How Does A Synthetic Antiviral Developed For Influenza Virus Inhibit Other Viruses? (Stephen Polyak, University of Washington) 2018-04-05 12:00: Alternative Cell Death Pathways in Antiviral Host Defense (Edward Mocarski, Emory University School of Medicine, Atlanta, USA) 2018-04-19 12:00: A Universal Approach to Optimise the Folding and stability of Pre-fusion-Closed Viral Enveloped Trimers (Johannes Langedijk, Janssen Vaccines & Prevention, Leiden, The Netherlands) 2018-04-26 12:00: Mechanisms of influenza A virus modulation of host membrane trafficking (Maria Amorim, Instituto Gulbenkian de Ciência, Oeiras, Portugal) 2018-05-10 12:00: In pursuit of a broad spectrum antiviral: High resolution structures of antiviral targets in the calnexin cycle (Nicole Zitzmann, University of Oxford) 2018-05-24 12:00: Role of RNA chaperons in segment assortment and RNA packaging of dsRNA viruses (Roman Tuma, Astbury Centre for Structural Molecular Biology, University of Leeds) 2018-06-14 12:00: Cell-Autonomous Mechanisms of HIV Suppression (Michael Malim, King's College London) 2018-10-04 12:00: Ubiquitin-mediated regulation of innate immune signaling during influenza virus infection (Sumana Sanyal, University of Hong-Kong, Hong-Kong) 2018-10-18 12:00: The viral capsid, a critical determinant of Enterovirus pathogenicity (Caroline Tapparel, University of Geneva, Switzerland) 2018-11-01 12:00: Influenza virus-host cell interactions (Nadia Naffakh, Institut Patsur, Paris, France) 2018-11-08 12:00: Vaccines for Notorious Zoonotic Viruses (Jonathan Heeney, University of Cambridge) 2018-11-29 12:00: Emerging virus spillover - overcoming the entry-barrier (Jonathan Ball, University of Nottingham) 2019-01-31 12:00: Viruses and the circadian clock: Rhythms, replication and pathogenesis (Rachel Edgar, Imperial College London) 2019-02-14 12:00: RNA-binding proteins step into the host-virus battlefront (Alfredo Castello, University of Oxford) 2019-02-28 12:00: Spatiotemporal regulation of host immune defences to HSV-1 infection (Chris Boutell, University of Glasgow) 2019-03-14 12:00: Hitchin' a ride: how herpesviruses modulate host-cell membrane trafficking (Dr Stephen Graham (University of Cambridge)) 2019-03-21 12:00: Bluetongue virus structure and replication (Polly Roy, London School of Hygiene and Tropical Medicine) 2019-03-28 12:00: RNA interference as an antiviral immunity in mammals (Xi Zhou, Wuhan Institute of Virology, China) 2019-04-25 12:00: Functional interactions between components involved in alphavirus regulation (Andres Merits, University of Tartu, Estonia) 2019-05-02 12:00: Merkel cell polyomavirus: the role of the early gene products during viral life cycle and Merkel cell cancer pathogenesis (Nicole Fischer, University of Hamburg, Germany) 2019-05-23 12:00: Regulating the balance of cytomegalovirus latency and reactivation through the viral GPCR US28 (Christine O'Connor, Cleveland Clinic, USA) 2019-06-06 12:00: Studying viruses in people using mathematics (Dr Chris Illingworth ( Department of Genetics, Cambridge)) 2019-06-20 12:00: Hijacking the Golgi: insights into the mechanism of Orthobunyavirus assembly in mammalian cells (Luis da Silva, University of São Paulo, Brazil) 2019-06-27 12:00: 'Hitchin' a ride: how herpesviruses modulate host-cell membrane trafficking (Dr Stephen Graham (University of Cambridge)) 2019-08-19 12:00: Antibodies against Ebola and Lassa: A Global Collaboration (Erica Ollmann Saphire, La Jolla Institute for Immunology) 2019-10-03 12:00: Can plant viruses manipulate their transmission by insects and influence the evolution of their hosts? (John Carr, Department of Plant Sciences, University of Cambridge) 2019-10-17 12:00: A novel mechanism of stress response antagonism by viral accessory proteins (Frank van Kuppenveld, University of Utrecht) 2019-11-14 12:00: Living with a million-year long infection (George Kassiotis, Frances Crick Institute) 2019-11-28 12:00: Antiviral Immunity against dengue and Zika viruses in Aedes mosquitoes (João Trindade Marques, Federal University of Minas Gerais, Brazil) 2020-02-13 12:00: Vector-host interactions and innate immunity in hematopoietic stem cell gene engineering (Anna Kajaste (Ospedale San Raffaele Milan)) 2020-02-27 12:00: African swine fever virus mechanisms for evading host defences and application to vaccine development (Linda Dixon (Pirbright Institute)) 2020-03-12 12:00: To be confirmed (Neva Caliskan (University of Wurzburg)) 2023-02-02 12:00: The interplay between cell cycle and immunity in the setting of viral infection (Dr Petra Mlcochova. Department of Medicine/Jeffrey Cheah Biomedical Centre) 2023-02-23 12:00: Using cryo-EM to unravel bunyavirus native RNPs and endosomal K+ requirement during entry (Dr Juan Fontana Jordán de Urriés. University of Leeds) 2023-03-09 12:00: Double-edged swords: innate and adaptive immune factors that inhibit or promote SARS-CoV-2 entry (Prof. Stuart Neil King's College London) 2023-03-23 12:00: Human inborn errors of immunity: revealing key mechanisms of antiviral immunity (Dr Vanessa Sancho-Shimizu. Imperial College London) 2023-04-27 12:00: An ancient DNA perspective on virus evolution (Dr Charlotte Houldcroft. Department of Genetics, University of Cambridge, UK) 2023-05-18 12:00: Exploiting the host: viral co-option of RNA modification and decay pathways (Dr Hannah Burgess. University of Surrey, UK.) 2023-05-25 12:00: Organoid models for human picornaviruses: from gut to brain (Dr Katja Wolthers. Amsterdam UMC, the Netherlands) 2023-06-08 12:00: The virome of insect vectors (Dr Ioannis Karakasiliotis. Medical School, Democritus University of Thrace, Greece)