Biophysics Colloquia - (Chemistry) 2006-02-24 10:00: NMR studies of protein-protein interactions involved in chromatin structure (Prof. Ernest Laue, Department of Biochemistry, University of Cambridge) 2006-03-03 10:00: NMR based investigation of protein molten globule states (Dr Christina Redfield, Department of Chemistry, University of Oxford) 2006-03-10 10:00: Bacterial chemotaxis: using computer models to unravel mechanism (Prof. Dennis Bray, Department of Physiology, Development and Neuroscience) 2006-03-17 10:00: Mass spectrometry for determination of protein quaternary structrure? (Dr Brandon Ruotolo, Robinson Group, Department of Chemistry, University of Cambridge) 2007-11-28 10:30: Protein misfolding: Influence of the cellular environment (Anne Bertolotti - LMB - Cambridge) 2007-11-30 10:30: Elucidating the structural and molecular basis of alpha-synuclein toxicity in Parkinson's disease and related synuleinopathies (Prof Hilal Lashuel) 2007-12-05 10:30: Mass spectrometry and structure, dynamics and function of the small heat shock proteins (Justin Benesch) 2007-12-11 10:30: Structure and antigenicity of amyloid fibrils (Marcus Fandrich) 2008-01-30 10:30: Elucidating molecular mechanisms on and off the pathway to amyloid deposition (Andrew Miranker) 2008-02-06 10:30: Plasmid addiction and toxin-antitoxin systems : paradigms for the study (Lode Wyns) 2008-02-13 10:30: A structural approach to polyglutamine diseases (Laura Masino) 2008-02-20 10:30: A structural approach to polyglutamine diseases (Vittorio Bellotti) 2008-02-27 10:30: 85 mutants, 70 phi-values, 4 years, and one overdue PhD: (Adrian Nickson) 2008-03-12 10:30: Electronic Energy Transfer/Migration & Biomacromolecular Structure (Lennart Johansson) 2008-03-19 10:30: Nascent chain folding on the ribosome by NMR spectroscopy (Shang-Te Danny HSU) 2008-04-16 10:30: The Tumour Suppressor p53: Structure,Function-Rescue (Alan Fersht) 2008-04-23 10:30: A New Kind of Protein-DNA Interaction in Replication Termination (Nick Dixson) 2008-04-30 10:30: On the Quaternary Structure of Macromolecular Protein Complexes in the Absence of Bulk Solvent (Brandon T. Ruotolo) 2008-05-07 10:30: Physical Insights into Protein Aggregation (Tuomas Knowles) 2008-10-08 10:30: Flux Control Analysis and the Systems Biology of the Eukaryotic Cell (Steve Oliver - Cambridge System Biology Centre- University of Cambridge) 2008-10-15 10:30: Determination of the Stoichiometry of Intact Membrane Protein Complexes using Mass Spectrometry (Nelson Barrera, University of Cambridge) 2008-10-29 10:30: Molecular Dynamics in Living Cells (Gabriele Kaminski Schierle, University of Cambridge) 2008-11-05 10:30: Bacterial actin: plasmid segregation by ParMRC (Jan Loewe, MRC-LMB) 2008-11-12 10:30: Pilus Formation Across the Bacterial Outer Membrane by the Chaperone/Usher Pathway (Gabriel Waksman, Birkbeck College) 2008-11-19 10:30: Structural Reorganisation and Potential Toxicity of Oligomeric Species (Giorgio Favrin, University of Cambridge) 2008-11-26 10:30: Everything you wanted to know about haem proteins, but were afraid to ask! (Paul Barker, University of Cambridge) 2009-01-21 10:30: Title to be confirmed (Helen Saibil, Birkbeck College) 2009-02-18 10:30: Probing myosin dynamics (Clive R. Bagshaw) 2009-02-25 11:00: Structural elucidation of the self-assembly mechanism of amyloid fibrils (Sheena Radford, University of Leeds) 2009-03-04 10:30: Tales of a two-stroke motor: allostery in the mechanism of the GroE chaperonin (Steve Burston) 2009-03-11 10:30: Extracellular chaperones and their role in the disposal of misfolded proteins from extracellular spaces (Justin Yerbury) 2009-03-18 10:30: Alpha-synuclein and protein aggregation (Chris Waudby) 2009-04-29 10:30: Title to be confirmed (Stefan Wallin) 2009-05-13 10:30: Title to be confirmed (Dafydd Jones) 2009-10-14 10:30: Exploring the folding energy landscape of a series of design consensus TPR proteins (Dr Ewan Main Department of Chemistry, University of Sussex) 2009-10-21 10:30: “Mechanisms of Prion and PolyQ Misfolding” (Prof Sarah Perrett, Chinese Academy of Sciences, Beijing) 2009-10-28 10:30: “Dissecting the membrane dynamics of amyloid oligomers at a single molecule level” (Dr Martino Calamai, University of Florence) 2009-11-04 10:30: “Peptides in solution, aggregates, and membranes: 2DIR spectroscopy as a probe of structure and function.” (Prof James Skinner, University of Wisconsin - Madison) 2009-11-11 11:30: “Structure and dynamics of globular and disordered proteins from Residual Dipolar Couplings” (Dr Xavier Salvatella, Institute for Research in Biomedicine, Barcelona) 2009-11-18 10:30: “Structural disorder and induced folding within the replicative complex of measles virus: experimental assessment and functional implications”. (Dr Sonia Longhi, Universities of Aix - Marseilles) 2009-11-25 10:30: “Towards a quantitative assessment of amyloid formation in vitro and in vivo by mulitparametric fluorescence microscopy” (Dr Carlos Bertoncini, Department of Chemistry, University of Cambridge) 2009-12-02 10:30: “Evolution & Dynamics of Protein Complexes” (Dr Sarah Teichmann, MRC-LMB, Cambridge) 2009-12-09 10:30: “Understanding protein aggregation in bacteria” (Dr Salvador Ventura, Autonomous University of Barcelona) 2010-01-27 10:30: Information-driven modelling of biomolecular complexes. (Prof. Alexandre Bonvin, Faculty of Science, Utrecht University) 2010-02-03 10:30: Protein misfolding in Alzheimer's disease: a neuroscientist takes lessons in biophysics (Dr Leila Luheshi, University of Cambridge) 2010-02-10 10:30: PDI and oxidative protein folding: conformations, dynamics and substrate interactions (Prof. Robert Freedman, University of Warwick) 2010-02-17 10:30: Advances in protein structure determination using NMR chemical shifts. (Dr Michele Vendruscolo, Department of Chemistry, University of Cambridge) 2010-02-22 17:00: Sequencing genomes and sequences in the genome: from chemistry to medicine (Prof. Shankar Balasubramanian, Department of Chemistry, University of Cambridge) 2010-03-03 10:30: The highs and lows of enzyme catalysis (Dr Colin Jackson, Institut de Biologie Structurale, Grenoble, France) 2010-03-10 10:30: Cyclophilin A: HIV-1 cofactor or antiviral? (Dr Leo James, MRC-LMB, Cambridge) 2010-03-17 10:30: Do cells care about physics? (Dr Jochen Guck, Cavendish Laboratory, University of Cambridge) 2010-04-21 10:30: Adapting to unfolded protein load in the endoplasmic reticulum (Prof. David Ron (University of Cambridge)) 2010-05-05 10:30: NMR studies of a helical 7-transmembrane receptor (Dr. Daniel Nietlispach (University of Cambridge)) 2010-05-12 10:30: Evolutionary strategies to prevent protein aggregation (Dr. Annalisa Pastore (National Institute for Medical Research, London)) 2010-05-19 10:30: Fibril fragmentation in amyloid assembly and cytotoxicity - When size matters (Dr. Wei-Feng Xue (Astbury Centre for Structural Molecular Biology, Leeds)) 2010-05-26 10:30: NMR Toolkit for studying biomolecular folding (Dr. Danny Hsu (University of Cambridge)) 2010-06-02 10:30: TBA (Dr. Monika Fuxreiter (Institute of Enzymology, BRC, Hungarian Academy of Sciences)) 2010-06-11 10:30: From pathology to function: the many faces of fibrillation (Dr. Daniel Otzen (Aarhus University)) 2010-06-11 10:30: From pathology to function: the many faces of fibrillation (Dr. Daniel Otzen (Aarhus University)) 2010-07-12 12:00: “Disordered Proteins and their Dynamic Complexes in Biological Regulation” (Prof. Julie Forman-Kay (University of Toronto))