Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research


2008-02-22 09:00: Registration at CIMR reception (.)

2008-02-22 09:10: Introduction (Professor Paul Luzio, Director of CIMR)

2008-02-22 09:15: Cells and gels - questions a physicist asks (Professor Athene Donald, Director, Physics of Medicine, Cavendish Laboratory)

2008-02-22 09:25: Antitrypsin deficiency and the serpinopathies (Professor David A Lomas, CIMR)

2008-02-22 09:35: Soft Matters - biomechanics in cancer diagnosis and nerve regeneration (Dr. Jochen Guck, Cavendish Laboratory (University of Cambridge))

2008-02-22 09:45: Autophagy upregulation - a possible therapeutic strategy for neurodegenerative conditions like Huntington's disease (Professor David Rubinsztein, CIMR)

2008-02-22 09:55: Discussion (All)

2008-02-22 10:05: Cell fate in the mammalian epidermis (Ben Simons (University of Cambridge))

2008-02-22 10:15: Incretin secretion - small currents matter. (Dr Frank Reimann, CIMR)

2008-02-22 10:25: Nucleic acid structures - predicting formation and function (Julian Huppert, Cavendish Laboratory (University of Cambridge))

2008-02-22 10:35: Discussion (All)

2008-02-22 10:45: Coffee Break (All)

2008-02-22 11:00: Intracellular function and motor properties of myosin VI (Dr Folma Buss, CIMR)

2008-02-22 11:10: Optical micromanipulation and quantifying Images (Dr Pietro Cicuta, Cavendish Laboratory (University of Cambridge))

2008-02-22 11:20: Investigating incretin hormone secretion by single cell dynamic fluorescence imaging. (Dr Fiona Gribble, CIMR)

2008-02-22 11:30: Modelling semiflexible chains, filaments, and their networks (Professor Eugene Terentjev, Cavendish Laboratory, University of Cambridge)

2008-02-22 11:40: Discussion (All)

2008-02-22 11:50: Serpin metastability and protease inhibition (Dr James Huntington)

2008-02-22 12:00: Statistical methods in X-ray crystallography (Professor Randy Read, CIMR)

2008-02-22 12:10: Molecular dynamics simulations of protein-surface interactions (Daniel Cole, Cavendish Laboratory)

2008-02-22 12:20: Discussion (ALL)

2008-02-22 12:30: Discussion over lunch (All Invited (please let me know for numbers))

2008-03-04 15:00: Monitoring single ion transporters at work: proton-driven rotation in FoF1-ATP synthase and domain swapping in P-type ATPase (Dr Michael Börsch  University of Stuttgart, Germany)

2008-03-07 13:00: The Vav1 nucleotide exchange factor: from structure to function (Victor Tybulewicz Nat. Inst. for Medical Research)

2008-03-14 13:00: Socs in myeloproliferative disease (Jim Johnston, Queens University, Belfast)

2008-04-04 13:00: Foxp3: evolution, pregnancy, therapy (Alex Betz, MRC-LMB, Cambridge)

2008-04-11 13:00: CD3 monoclonal antibodies to treat type 1 diabetes (Lucienne Chatenoud, INSERM, Hopital Necker, Paris, France)

2008-04-14 15:00: Mitochondrial FAS - from respiratory deficient yeast to cardiomyopathic mice (Kalervo Hiltunen, university of Oulu, Finland)

2008-04-28 15:00: Mitochondrial adaptation to high altitude hypoxia (Andrew Murray, Department of Physiology, Development and Neuroscience)

2008-04-28 16:00: A crystal structure based study of NhaA, a Na+/H+ antiporter with orthologues from bacteria to human (Etana Padan, Hebrew university of Jerusalem, Israel)

2008-05-02 13:00: Cytomegalovirus latency, reactivation and life and death decisions (John Sinclair, Dept of Medicine, University of Cambridge)

2008-05-09 13:00: Give us the tools, and we will finish the job (Stephen Sawcer, Dept of Clinical Neurosciences, University of Cambridge)

2008-05-14 15:00: 'Mitochondrial FAS - from respiratory deficient yeast to cardiomyopathic mice' (Professor Kalervo Hiltunen, University of Oulu, Finland)

2008-05-16 13:00: Toll-like receptor signal transduction in infection and inflammation (Luke O'Neill, Trinity College, Dublin)

2008-05-21 15:00: 'The motile response of bacteria to pH jumps' (Professor Shahid Khan, LUMS School of Science and Engineering, Lahore, Pakistan and Molecular Biology Consortium, Chicago, USA)

2008-05-22 15:00: 'Construction of the bacterial flagellar rotor (Professor Shahid Khan, LUMS School of Science and Engineering, Lahore, Pakistan and Molecular Biology Consortium, Chicago, USA)

2008-05-23 13:00: Take your pick - epitope selection by effector and regulatory T cells in autoimmune disease (Rob Barker, Head of Immunology Programme, Inst. of Medical Sciences, University of Aberdeen)

2008-05-27 15:00: 'Light triggers for visualization of signal protein dynamics' (Professor Shahid Khan, School of Science and Engineering, Lahore, Pakistan and Molecular Biology Consortium, Chicago, USA)

2008-05-28 15:00: 'A crystal structure based study of NhaA, a Na+/H+ antiporter with orthologues from bacteria to human' (Professor Etana Padan, Hebrew University of Jerusalem, Israel)

2008-05-30 13:00: Pathophysiology of Autoimmune Disease (David Hafler, Centre for Neurologic Diseases, Harvard medical School, Boston, USA)

2008-06-06 13:00: Perturbation of the ubiquitin-proteasome system in Epstein-Barr virus infection and oncogenesis (Maria Masucci, Dept of Cell and Molecular Biology, Karolinska Institute, Sweden)

2008-06-13 13:00: Transplantation tolerance - strategies to promote and biomarkers to measure (Robert Lechler, Vice Principal (Health), Guys Campus, King's College London)

2008-06-20 13:00: Microarrays to identify human Th1 and Th2-specific effector molecules (David Cousins, MRC/Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London)

2008-06-27 13:00: Understanding genetics of type 1 diabetes: from common to rare disease variants (Sergey Nezhentsev, CIMR, University of Cambridge)

2008-07-04 13:00: How Satan smote Job: The molecular cause of the hyper IgE syndrome - Are th17 cells really the bad guys? (Bodo Grimbacher, Clinical Immunology, Royal Free Hospital, London)

2008-07-11 13:00: Novel approaches for vaccine design: Bypassing Treg activity enhances T cell-mediated immunity (Tim Sparwasser, Institut fur Medizinische Mikrobiologie, Immunologie und Hygiene, Munich)

2008-09-19 13:00: Cell-biology of antigen cross-presentation (Christian Kurts, Friedrich-Wilhelms-Universität, Bonn, Germany)

2008-09-26 10:30: The Pathogenesis of Autoimmunity: The IL-2-FOX P3 Negative Feedback Pathway (Kendall Smith)

2008-09-26 13:00: Lymphocyte egress: from S1P to Arp2/3 (Jason Cyster, Howard Hughes Medical Centre, UCSF)

2008-10-03 13:00: Regulators, some 'complement'ary stories (Susan Lea, Sir William Dunn School of Pathology, Oxford)

2008-10-10 13:00: The genetic basis of ankylosing spondylitis (Matt Brown, University of Queensland, Brisbane)

2008-10-16 14:30: Rational vaccine design – dreams, genes and reality (Alex von Gabain, Intercell AG, Vienna)

2008-10-17 13:00: Targeting HIV-1 Gag into the DRiP-pathway enhances its presentation by MHC class I (Ulrich Schubert, University of Erlangen, Germany)

2008-10-24 13:00: Matching Lymphocyte Metabolism and Migration (Doreen Cantrell, Cell Biology and Immunology, University of Dundee)

2008-10-30 13:00: Immunity to self co-generates regulatory T cells (Len Harrison, Walter and Eliza Hall Institute of Medical Research, Melbourne)

2008-11-05 12:00: Cell death inhibitors: from Baculovirus to Bedside (David Vaux, Latrobe University, Melbourne, Australia)

2008-11-07 13:00: How does CTLA-4 control T cell activation? A story of Treg and regular Ts (David Sansom, University of Birmingham)

2008-11-14 13:00: The intracellular biology of Salmonella (David Holden, Imperial College, London)

2008-11-21 13:00: Cohesin, CTCF and gene regulation in the immune system (Matthias Merkenschlager, MRC Clinical Sciences Centre, London)

2008-12-02 12:00: Delineating the Fanconi Anaemia DNA Repair Defect (Dr K J Patel:  MRC Laboratory of Molecular Biology)

2008-12-05 13:00: Peptide-based immunotherapy for coeliac disease (Bob Anderson, Walter & Eliza Hall Institute, Melbourne, Australia)

2009-01-16 13:00: Effector differentiation during development of the memory CD8+ T cell (Douglas Fearon, Wellcome Immunology Unit, University of Cambridge)

2009-01-23 13:00: Restriction of enveloped virus particle release by tetherin/CD317 (Stuart Neil, Kings College, London)

2009-01-30 13:00: Complement genetic variations and disease. Functional and Structural insights into the assembly and regulation of the alternative pathway C3-convertase (Santiago Rodriguez de Cordoba, Centro de Investigaciones Biologicas (CSIC) Madrid)

2009-02-13 13:00: Learning about innate immune signalling from viruses (Andrew Bowie, Trinity College, Dublin)

2009-02-20 13:00: Cancelled (Duncan Conrad)

2009-02-27 13:00: Regulatory B cells in health and in disease (Claudia Mauri)

2009-03-06 13:00: Preserving and restoring gut barrier function (Simon Carding, University of East Anglia)

2009-03-13 13:00: Inhibitors of innate immunity from vaccinia virus (Geoff Smith, Imperial College, London)

2009-03-25 12:30: Roles of PD-1 and PD-L1 in regulating T cell activation and tolerance (Arlene Sharpe, Dept of Pathology, Harvard Medical School)

2009-03-27 13:00: Amphioxus immunity provides the ancestral form and inner workings of vertebrates immune system (Aniong Xu, Sun Yat-sen University, Guangzhou)

2009-04-24 13:00: Tolerance, autoimmunity and interleukin-2 (Abul Abbas, University of California)

2009-05-01 13:00: Targeting regulatory T cells in rheumatoid arthritis (Michael Ehrenstein, UCL, London)

2009-05-08 13:00: Transcriptional networks in macrophages (David Hume, Roslin Institute, Edinburgh)

2009-05-15 13:00: The biology of 'atypical' chemokine receptors (Rob Nibbs, Division of Immunology, Infection and Inflammation, Glasgow Biomedical Research Centre)

2009-05-22 13:00: SLP-76 is mandatory for TCR-mediated inside-out-signaling, but dispensable for CXCR4-mediated LFA-1 adhesion and migration of T-cells (Stefanie Kliche)

2009-05-29 13:00: Clues to autoimmunising mechanisms in patients with myasthenia gravis or AIRE mutations (Nick Willcox, Neuroscience, Weatherall Inst. for Molecular Medicine, University of Oxford)

2009-06-05 13:00: Autoimmunity to LAMP-2: a case for molecular mimicry in vasculitis (Andrew Rees, Institute of Clinical Pathology, Vienna)

2009-06-08 13:00: Functional genetics of PTPN22, a shared autoimmunity gene (Nunzio Bottini, Associate Member, La Jolla Institute for Allergy and Immunology, Division of Cell Biology, La Jolla, CA)

2009-06-12 13:00: The influence of signal strength on the differentiation of effector and memory T cells (Rose Zamoyska, University of Edinburgh)

2009-06-19 13:00: Signal sequences in protein targeting to the endoplasmic reticulum (Bernhard Dobberstein, ZMBH Universität Heidelberg, Germany)

2009-06-26 13:00: Visualising and analysing immune priming and infection in real time in vivo (James Brewer, Centre for Biophotonics, University of Strathclyde)

2009-07-03 13:00: Role of aryl hydrocarbon receptor in immune responses (Marc Veldhoen, NIMR, London)

2009-07-10 13:00: Catch me if you can. Anti HIV restriction factors, viral countermeasures and the Red Queen (Greg Towers, MRC Centre for Medical Molecular Virology, University College London)

2009-07-24 13:00: From molecules to maladies: TNF superfamily cytokines in autoimmune and inflammatory disease (Richard Siegel, Senior Investigator and Chief, Immunoregulation Section Autoimmunity Branch, NIAMS National Institutes of Health Bethesda, MD US)

2009-07-29 13:00: Factors influencing the acquisition of CD8+ T cell effector function (Alice Denton)

2009-07-31 13:00: NK Cells in reproduction, transplantation and cancer (Francesco Colucci - Lymphocyte Signalling and Development, The Babraham Institute, plus Centre for Trophoblast Research, University of Cambridge)

2009-09-18 13:00: How studying responses to Salmonella provides insights into the biology of B and T cells (Adam Cunningham, University of Birmingham)

2009-09-25 13:00: Can lamprey VLR antibodies be biomedically useful? (Max Cooper - Emory University School of Medicine, Atlanta)

2009-09-28 13:00: Through the Looking Glass - a New World of Proteins Enabled by Chemistry (Dr Stephen Kent (Department of Biochemistry and Molecular Biology, University of Chicago))

2009-09-29 13:15: HIF1 versus HIF2: how macrophages use hypoxic response to regulate nitric oxide (Randy Johnson - Division of Biological Sciences, at UCSD)

2009-10-02 13:00: New therapies for genetic disease (Peter Goodfellow)

2009-10-09 13:00: Integrins and immune function (Nancy Hogg, Cancer Research UK, Lincoln's Inn Fields Laboratories, London)

2009-10-15 14:30: Immunology of the thymus: Cellular and molecular aspects (Georg Holländer, Pediatric Immunology, Center for Biomedicine and The University Children's Hospital of Basel)

2009-10-16 13:00: Prospects for gene therapy for primary immunodeficiency (Adrian Thrasher, UCL, Institute of Child Health, London)

2009-10-23 13:00: PI3K in lymphocyte development and activation (Klaus Okkenhaug, Babraham Institute, Babraham, Cambridge)

2009-10-30 13:00: Chronic antigenic stimulation and the human immune system : lessons from herpesviruses and cancer (Paul Moss, University of Birmingham)

2009-11-06 13:00: Plastic T cells: from mechanism to prediction in childhood arthritis (Lucy Wedderburn - University College London)

2009-11-13 13:00: Neutrophil extracellular traps (Arturo Zychlinsky, MPI for Infection biology, Berlin)

2009-11-20 13:00: Commonalities in the genetic control of liver disease induced upon bacterial infection and type 1 diabetes (Jochen Mattner, Cincinnati Children's Hosp. Medical Center, Cincinnati, Ohio)

2009-11-27 13:00: Novel crosstalk between the ER stress and TLR signaling pathway (Jane Goodall, Dept of Medicine, University of Cambridge)

2009-12-04 13:00: Innate regulation of dendritic cell function (Caetano Reis e Sousa, Cancer Research UK, Univeristy College, London)

2010-01-12 16:00: Endoplasmic Reticulum Stress and Intestinal Inflammation (Arthur Kaser - Innsbruck Medical University)

2010-01-15 13:00: Probing the Unfolded Protein Response with small molecules (David Ron - Institute of Metabolic Sciences, University of Cambridge)

2010-01-19 12:30: How can the immune system be regulated? (Herman Waldmann, Sir William Dunn School of Pathology, University of Oxford)

2010-01-22 13:00: Asymmetric Immune control by Foxp3+ regulatory T cells (Adrian Liston - Autoimmune Genetics Laboratory VIB/K.U. Leuven, Belgium)

2010-01-29 13:00: Invariant NKT cell receptors: innate-type recognition with an adaptive gear (Stephan Gadola, Division of Infection, University of Southampton)

2010-01-29 15:00: Individual and Allele specific chromatin: discovery and consequences (Ewan Birney - European Molecular Biology Laboratory, European Bioinformatics Institute)

2010-02-04 16:00: The Wellcome Trust Thailand Major Overseas Programme - current research and future challanges (Nick Day, Professor of Tropical Medicine, Director of the Mahidol Oxford Clinical Research Unit, Thairland)

2010-02-05 13:00: MicroRNA regulation in B cell fate (Almudena Ramiro - CNIIO Spanish National Cancer Research Centre, Madrid)

2010-02-19 13:00: E4bp4 and NK cells (Hugh Brady, Division of Cell and Molecular Biology, Imperial College)

2010-02-22 11:30: Generation of stable monoclonal antibody-producing human memory B cells by genetic programming (Hergen Spits - Academic Medical Centre, University of Amsterdam, The Netherlands)

2010-02-26 13:00: Immunotherapy of established disease caused by high risk Human Papilloma Virus (Cornelis Melief, Leiden University Medical Center, Dept. Immunohematology and Bloodtransfusion)

2010-03-05 13:00: Human cytomegalovirus and its obsession with Natural Killer cells (Gavin Wilkinson, Medical Microbiology, University of Cardiff)

2010-03-12 12:30: Investigating the lymphoid stress-surveillance response (Adrian Hayday - Division of Immunology, Infection & Inflammatory Diseases, Kings College, London)

2010-03-16 12:30: Calcium-dependent T-cell activation (Markus Hoth, University of Saarland, Germany)

2010-03-19 13:00: Making HIV epitopes - antigen processing and CTL responses (Astrid Iversen - Weatherall Instittue of Molecular Medicine, Oxford)

2010-03-26 13:00: Functional genomic landscapes by gene disruption and parallel sequencing connect genes to human disease (Jan Carette - Whitehead Institute, MIT, Boston)

2010-04-09 13:00: Dengue virus, innate immunity and disease control (Michael Jacobs - University College London, Infection and Immunity)

2010-04-16 13:00: Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4 (Michelle Janas, Babraham Institute, Babraham, Cambridge)

2010-04-23 13:00: The Role of P13P during initiation of autophagy (Nicholas Ktistakis, Babraham Institute, Babraham)

2010-04-30 13:00: Microenvironmental effects of apoptosis in vivo and in vitro: uncovering a "new biology" of cell death? (Chris Gregory - University of Edinburgh, MRC Centre for Inflammation Research)

2010-05-07 13:00: How do maternal NK cells affect reproductive success? (Ashley Moffett, Department of Pathology, University of Cambridge)

2010-05-14 13:00: T cell signals that control motility and interactions with dendritic cells in lymph nodes (Prof. Chris Rudd, Department of Pathology, University of Cambridge)

2010-05-18 17:00: Host response to micobacterium abscessus (Dr Jean-Louis Herrmann, Hopital Saint-Louis, Paris)

2010-05-21 13:00: Antibody-mediated graft rejection - a cytotopic therapeutic approach (Richard Smith)

2010-05-28 13:00: Imaging of T cell migration in slices of murine lymph nodes and human tumors (Emmanuel Donnadieu - Department de Biologie, Cellulaire, Institut Cochin, Paris)

2010-06-04 13:00: How cells defend their cytosol against baterial attack (Felix Randow - LMB-MRC, Cambridge)

2010-06-04 16:00: In vivo imaging of haematopoietic stem and progenitor cells interacting with their niche(s) (Cristina Lo Celso, Imperial College, London)

2010-06-11 13:00: Unexpected coding capacities in the influenza A virus genome (Paul Digard, Department of Pathology)

2010-06-11 16:00: Interactions between a cell signalling pathway and a haematopoietic transcriptional network (John Pimanda, University of New South Wales)

2010-06-16 12:00: T cell turnover in vivo using stable isotope labelling (Kristin Ladell - National Institute of Health, Bethesday/University of Cardiff)

2010-06-16 12:00: High definition immune profiling of antigen-specific T cells: implications for disease pathogenesis and vaccine design (David Price National Institute of Health/Cardiff University)

2010-06-18 13:00: Forward and reverse genetics of memory T lymphocytes (Philip Ashton-Richardt)

2010-06-21 14:00: Role of Cytomegalovirus miRNAs in Virus Pathogenicity (Lars Dolken, Max von Pettenkofer-Institute, Munich)

2010-06-28 13:00: Understanding T cell: B cell interactions through studies of X-linked lymphoproliferative syndrome (Pam Schwartzberg, National Human Genome Research Institute, Genetic Disease Research Branch, Bethesda)

2010-07-02 13:00: Genetics of a transmissible facial tumour in the Tasmanian devil (2 talks, same title) (Elizabeth Murchison and Hannah Siddle)

2010-07-29 13:00: Modeling APL pathogenesis through therapy response (Hugues de Thé MD, PhD, University of Paris, Head, INSERM/CNRS/University Paris 7)

2010-09-09 16:00: Initiation and progression of leukemia – lessons from Down Syndrome (Shai Izraeli, Tel Aviv University, Israel)

2010-09-10 13:00: Alpha beta and gamma delta T cell recognition of transformed self via novel antigenic targets (Ben Willcox, CRUK Cancer Centre, University of Birmingham - Hosted by John Trowsdale)

2010-09-17 13:00: Tissue stem cell fate: lessons from lineage tracing and statistical physics (Ben Simons, Cavendish Laboratory, University of Cambridge - Hosted by Patrick Sissons, Regius Professor of Physic)

2010-10-01 13:00: Blimp1 and IRF4 are jointly required for the differentiation of effector regulatory T cells (Axel Kallies, The Walter and Eliza Hall Institute of Medical Research, Melbourne - Hosted by Ken Smith)

2010-10-08 13:00: Multiple sclerosis: functional genetics (Lars Fugger, Weatherall Institute of Molecular Medicine, University of Oxford - Hosted by John Todd)

2010-10-15 13:00: The critical functions of transcription factor Bcl11b in T cell development and maintenance of T cell identity (Pentao Liu, Sanger Institute, Wellcome Trust Genome Campus, Hinxton - Hosted by Francesco Colucci)

2010-10-15 16:00: Leukemic stem cells - a challenging adversary (Keith Humphries, Terry Fox Laboratories, Vancouver, Canada)

2010-10-22 13:00: Two lessons from bench to bedside: Why do we need to feed our gut with IL10 and a surprising role of antibodies in the innate immune defence to Candida (Bodo Grimbacher, UCL , Research Department of Immunology - Hosted by Ken Smith)

2010-10-29 13:00: Epigenetics - New regulators of gene expression (Steffen Gay, University Hospital, Zürich - Hosted by Hill Gaston)

2010-11-05 13:00: The septin cage: a novel assembly of host defense against cytosolic bacteria (Serge Mostowy, Institut Pasteur, Paris - Hosted by Felix Randow)

2010-11-11 15:00: Insights into the molecular basis of myelodysplastic syndrome (Ben Ebert, Department of Medicine, Harvard Medical School)

2010-11-12 13:00: Restriction of the felid retroviruses by BST2/tetherin (Brian Willett, Institute of Infection, Immunity and Inflammation, Glasgow)

2010-11-19 13:00: Macrophage lectins and the antifungal response (Philip Taylor, Dept of Infection, Immunity and Biochemistry, Cardiff - Hosted by Edwin Chilvers)

2010-11-22 16:00: T follicular helper cells in protective immunity and autoimmunity. (Carola Vinuesa, John Curtin School of Medical Research, Australian National University)

2010-11-26 13:00: Transcriptional control of CD4/CD8 lineage decision during T cell development (Wilfried Ellmeier, Medical University of Vienna - Hosted by Paul Lyons)

2010-12-03 13:00: Clonotypic determinants of biological outcome: the importance of the naive T cell repertoire (David Price, University of Cardiff - Hosted by Paul Lehner)

2010-12-08 12:00: B lymphocyte regulation of inflammation and autoimmunity (Professor Tom Tedder, Duke University)

2010-12-08 12:00: B lymphocyte regulation of inflammation and autoimmunity (Professor Tom Tedder, Duke University, USA - Hosted by Chris Rudd)

2010-12-10 13:00: Post-transcriptional control of inflammation (Paul Anderson, Brigham and Women's Hospital, Harvard Medical School - Hosted by Chris Rudd)

2010-12-17 13:00: ZnT8- a major autoantigen in human type 1 diabetes (Howard Davidson, University of Colorado, Denver - Hosted by Paul Luzio)

2011-01-14 13:00: A quantitative view of gene expression levels in T helper cells (Dr Sarah Teichmann, MRC Programme Leader, Computational Genomics, MRC Laboratory of Molecular Biology hosted by Doug Fearon)

2011-01-21 13:00: Th2 response induction by dendritic cells: lessons from pathogens (Dr Andrew S MacDonald, Institute of Immunology and Infection Research, University of Edinburgh hosted by Andrew McKenzie)

2011-01-28 13:00: The lectin activation pathway of complement and the mysteries of inflammatory pathologies (Professor Wilhelm Schwaeble, University of Leicester hosted by Doug Fearon)

2011-02-04 13:00: Paternal MHC linked to uterine vascular remodelling and feto-placental growth (Francesco Colucci, Centre for Trophoblast Research, University of Cambridge hosted by Linda Wicker)

2011-02-09 14:30: Understanding natural acquired malaria immunity or what malaria understands about the immune system that immunologists don’t (Susan Pierce, Chief, Laboratory of Immunogenetics, NIAID, NIH, Rockville hosted by Ken Smith)

2011-02-11 13:00: Intracellular Immunity: neutralizing viruses inside infected cells (Dr Leo James ( MRC-LMB, Cambridge) hosted by John Trowsdale)

2011-02-18 13:00:  Nuocytes: new insights in type-2 immunity (Andrew McKenzie, MRC Laboratory of Molecular Biology hosted by Ken Smith)

2011-02-25 13:00: Early events in B cell activation: from single molecules to living tissue (Facundo Batista, CRUK)

2011-02-25 16:00: Genetic complexity in MPN and MDS/MPN (Nick Cross, Univeristy of Southampton)

2011-03-04 13:00: Establishing the molecular basis of the persistence of immunological memory (David Tarlinton, WEHI, Melbourne hosted by Ken Smith)

2011-03-08 13:00: The generation of antibody-based diagnostics and therapeutics for emerging infectious diseases (Dr Paul MacAry, National University of Singapore hosted by Ken Smith)

2011-03-11 13:00: Investigations to determine causal molecules in Crohn’s disease and ulcerative colitis (Anthony Segal, Director, Centre for Molecular Medicine, UCL hosted by John Todd)

2011-03-14 13:00: Title to be confirmed (Speaker to be confirmed)

2011-03-18 13:00: Pathways of inflammation and tissue remodelling in immune-mediated inflammatory diseases: lessons from human arthritis (Dr Dominique Baeten, University of Amsterdam hosted by Hill Gaston)

2011-03-25 13:00: How we achieve tolerance for our mothers: Evidence for a layered Immune System in Humans (Dr Jeff Mold, Karolinska Institute, Stockholm, Sweden hosted by Alex Betz)

2011-04-01 13:00: Environment specific control of immune reactivity: lessons from studying mucosal immune responses in man (Professor Stefan Meuer, Ruprecht-Karls-Universität Heidelberg hosted by Chris Rudd)

2011-04-08 13:00: Local development of Follicular Helper T cells (Nicolas Fazilleau, Purpan Hospital, Toulouse hosted by Students/Post docs)

2011-04-15 13:00: Harnessing cytomegaloviral immune evasion for vaccine development (Klaus Frueh, Oregon Health & Science University hosted by Paul Lehner)

2011-04-18 10:30: Studying precancerous stem cells in mouse models of T cell leukaemia (Matthew McCormack, WEHI, Melbourne)

2011-05-13 13:00: Immune modulation via C-type lectins (Dr Veronique Braud, Institut de Pharmacologie Moleculaire et Cellulaire, Valbonne, France, hosted by Francesco Colucci)

2011-05-13 16:00: The development of HSCs: endothelial to hematopoietic transition (Elaine Dzierzak, Erasmus MC, Rotterdam)

2011-05-20 13:00: Essential role of lymph node stroma in orchestrating efficient immune responses (Dr Mark Coles, University of York, hosted by Andrew McKenzie)

2011-05-25 11:30: Gut, germs and genes: the role of the microflora in intestinal oncogenesis (Eyal Raz, University of California San Diego, hosted by Arthur Kaser)

2011-05-27 13:00: Mapping the functional interaction network of mammalian ER-associated degradation (John Christianson, Ludwig Institute for Cancer Research, Oxford hosted by Paul Lehner)

2011-06-01 10:00: Genes, cells and pathways - Post GWAS (Ramnik Xavier, Harvard Medical School Broad Institute of MIT and Harvard, hosted by John Todd)

2011-06-03 13:00: War and peace at the mucosal interface in the gut (Claudio Nicoletti, Institute of Food Research, Norwich hosted by Hill Gaston/Jane Goodall)

2011-06-07 16:00: Autophagy in the hematopoitic system (Professor Katia Simon, Weatherall Institute of Molecular Medicine, Oxford University, hosted by Andres Floto)

2011-06-09 13:30: Genetics and therapy of AML: role of mutations in the epigenetic machinery (Ross Levine, Memorial Sloan-Kettering, New York)

2011-06-10 13:00: Making and br(e)aking CD effector/memory responses (Professor Peter Lane, University of Birmingham, hosted by Students/Post docs)

2011-06-17 13:00: Immunglobulin enhancers and AID targeting during class switch recombination (Dr Amine Khamlichi, University of Toulouse, France hosted by Michael Neuberger)

2011-06-17 16:00: Why do we need a Fanconi Anaemia DNA repair pathway? (KJ Patel, MRC LMB, Cambridge)

2011-06-24 13:00: Between tolerance and vigilance - host-microbial homeostasis at the intestinal epithelium (Professor Mathias Hornef, Hannover Medical School hosted by Felix Randow)

2011-07-01 13:00: Imaging neutrophilic inflammation in vivo: what we can learn from studies in zebrafish (Stephen Renshaw, University of Sheffield, hosted by Edwin Chilvers)

2011-07-06 10:00: Development of hematopoietic stem cells: an outline of the final scenario (Shin-Ichi Nishikawa, Riken CDB, Kobe)

2011-07-07 12:30: Control of immune homeostasis by regulatory T cells (Dr Sasha Rudensky, The Memorial Sloan-Kettering Cancer Center New York, hosted by  Paul Lehner)

2011-07-08 13:00: Retinoic acid: An immune morphogen? (Randy Noelle, Dartmouth University and King's College London hosted by Chris Rudd)

2011-07-15 13:00: NOD2-dependent autophagy and Crohn's disease (Dr Alison Simmons, Nuffield Dept of Clinical Medicine, University of Oxford, hosted by Arthur Kaser)

2011-07-22 13:00: Regulation of immune responses to pancreas-expressed antigens: role of CTLA-4 (Dr Lucy Walker, University of Birmingham, hosted by John Todd)

2011-09-02 13:00: Molecular Mechanisms in cytotoxicity by SLAM family receptors (Dr Marion Brown, Dunn School of Pathology, Oxford, hosted by Gillian Griffiths)

2011-09-09 13:00: Salmonella diarrhea - from molecular analysis to the real infection (Professor Wolf-Dietrich Hardt, Institute of Microbiology, Zurich, hosted by Felix Randow)

2011-09-14 16:00: Approaches to and biomarkers of transplantation tolerance (Professor Robert Lechler, King's College, London, hosted by Ken Smith)

2011-09-16 13:00: Innate Lymphoid Cells: An Emerging Family of Immune Effectors (Professor Jim di Santo, Institut Pasteur, Paris, France, hosted by Francesco Colucci)

2011-09-16 16:00: Genome-wide DNA methylation analysis in stem cells and cancer (Christoph Bock, Broad Institute)

2011-09-23 13:00: Multiplexed assays for studying immunologic diseases (Professor PJ Utz, Stanford School of Medicine, California, hosted by Paul Lyons)

2011-09-23 16:00: Chromatin, chromosome and nuclear dynamics, links to genome function (Peter Fraser, Babraham Institute)

2011-09-30 13:00: Journey to the Centre of Translation: In Situ Visualisation and Characterisation of Compartmentalised Protein Synthesis in Cells and Tissues (Alexandre David, Laboratory of Viral Diseases, NIAID, NIH, Bethesda, USA, hosted by Paul Lehner/Ken Smith)

2011-10-07 13:00: Bridging the Gap: Computational Biology and Trafficking of MHC Class I (Professor Sebastian Springer, Jacobs University, Bremen, hosted by John Trowsdale)

2011-10-13 15:00: Control of inflammation by natural and synthetic histone mimics (Professor Sasha Tarakhovsky, The Rockefeller University, New York, hosted by Ken Smith)

2011-10-14 13:00: Hedgehog signalling in T-cell differentiation (Dr Tessa Crompton, Institute for Child Health, University College London, hosted by Gillian Griffiths)

2011-10-21 13:00: HIV-related mortality past and present (Professor Sebastian Lucas, King's College London School of Medicine, hosted by Leo James)

2011-11-04 13:00: Chaperoning antibody diversification (Dr Javier di Noia, Insitut de Recherches Cliniques de Montreal, hosted by Michael Neuberger)

2011-11-07 16:00: Long non-coding and extracoding RNAs in normal haematopoiesis and leukemia (Dan Tenen, Cancer Science Institute of Singapore and Harvard Medical School)

2011-11-11 13:00: Retinoic acid: An immune morphogen? (Dr Randy Noelle, Dartmouth University and King's College, London, hosted by Chris Rudd)

2011-11-18 13:00: Pattern Recognition Receptors: therapeutic targets for allergic as well as infectious disease? (Dr Clare Bryant, Dept of Clinical Veterinary Medicine, University of Cambridge, hosted by Edwin Chilvers)

2011-11-25 13:00: MHC-determined resistance to a herpes virus: some new pictures of peptide motifs for class I and TAP molecules (Professor Jim Kaufman, Dept of Pathology, University of Cambridge, hosted by Paul Lehner)

2011-12-02 13:00: Compartments and continua of the immune responses to commensal intestinal microbes (Professor Andrew MacPherson, University of Bern, Switzerland, hosted by Arthur Kaser)

2011-12-06 16:00: Commitment and plasticity in the B cell lineage (Research Institute of Molecular Pathology Vienna, Austria)

2011-12-09 13:00: Title to be confirmed (Dr Richard Blumberg, Harvard School of Medicine, hosted by Students and Postdocs, Smith lab)

2012-01-20 13:00: Transcriptional and chromatin regulation of T helper cell differentiation (Dr Richard Jenner, University College London, hosted by Sarah Teichmann)

2012-01-27 13:00: The αβTCR uses an antibody‐like strategy to engage MHC‐peptide (Professor Julian Dyson Dept of Medicine, Imperial College, London. Hosted by Linda Wicker.)

2012-01-27 16:00: How do enhancers and promoters interact and what are the consequences ? (Doug Higgs, Weatherall Institute, Oxford,)

2012-02-03 13:00: Targeting B cells in Cardiovascular Diseases (Professor Ziad Mallat, Department of Medicine, University of Cambridge)

2012-02-07 12:00: Transcriptional control of EMT and malignant tumor progression (Prof Gerhard Christofori, University of Basel, Switzerland)

2012-02-08 11:00: Molecular mechanisms of human T helper cell differentiation to functionally distinct subsets (Professor Riitta Lahesmaa Turku Centre for Biotechnology, Finland. Hosted by Sarah Teichmann.)

2012-02-10 13:00: Immunity to Streptococcus pneumoniae (Dr Jerry Brown University College London. Hosted by Andres Floto.)

2012-02-17 13:00: Vitamin D and tuberculosis (Dr Adrian Martineau Queen Mary University of London, Barts and The London School of Medicine and Dentistry. Hosted by John Todd.)

2012-02-24 13:00: Development of Foxp3+ regulatory T cell: epigenetics and more… (Professor Jochen Huehn Helmholtz Centre for Infection Research, Germany. Hosted by Alex Betz.)

2012-03-02 13:00: Differentiation of plasma cells, and selection in the germinal centre. (Dr Kai Michael Toellner University of Birmingham, hosted by Elena Vigorito.)

2012-03-06 16:15: The thymus: 500 million years in the making (Professor Thomas Boehm Max Planck Institute of Immunobiology and Epigenetics, Freiberg, Germany. Hosted by Ken Smith.)

2012-03-09 13:00: Monocytes, macrophages & DCs development pathways that specify functions (Professor Frederic Geissmann King’s College London. Hosted by Hill Gaston.)

2012-03-15 14:30: Mechanisms of innate and adaptive T cell help to B cells during infection and immunity (Dr Irah King, Trudeau Institute. Hosted by Paul Lehner)

2012-03-16 13:00: Structural determinants underlying ubiquitin chain linkage specificity in NF-kB signalling (Dr Yogesh Kaluthu MRC LMB, Cambridge, hosted by Paul Lehner.)

2012-03-20 12:00: Novel connections between anti-viral innate immunity and metabolism: A Systems Biology Approach (Dr Hwjin Kim, Department of Genetics, Harvard Medical School. Hosted by Paul Lehner)

2012-03-23 13:00: Basophils in immune responses against helminths and allergens (Professor David Voehringer Friedrich Alexander University of Erlangen‐Nurnberg, Germany. Hosted by Andrew McKenzie.)

2012-03-23 16:00: Local interactions and genome-wide co-associations of proto-oncogenes: the short and the long of it. (Cameron Osborne, Babraham Institute)

2012-03-26 15:00: "The earliest events in T cell receptor activation" (Professor Kai Wucherpfennig, Dana Farber Cancer Institute, Harvard. Hosted by Ken Smith)

2012-03-30 13:00: Malaria and Salmonella: tolerance versus resistance (Professor Eleanor Riley London School of Hygiene & Tropical Medicine. Hosted by John Trowsdale.)

2012-04-03 12:00: Always on guard: p53 dynamics in single living cells (Dr Alexander Loewer, Berlin Institute for Medical Systems Biology, Max Delbrueck Center, Germany)

2012-04-13 13:00: "Into thin air: regulation of inflammatory gene expression by hypoxia" (Professor Cormac Taylor, UCD Conway Institute. Hosted by Edwin Chilvers)

2012-04-13 13:00: “CD45 and TIM-1: unique targets for induction of regulatory T and B cells in transplant tolerance" (Professor David Rothstein, University of Pittsburgh. Hosted by Chris Rudd)

2012-04-20 13:00: "Control of intercellular signalling by rhomboids and their relatives" (Dr Matthew Freeman, MRC Laboratory of Molecular Biology. Hosted by Paul Lehner)

2012-04-25 16:30: "Germinal center selection and the development of memory B and plasma cells" (Dr Mark Shlomchik, Yale School of Medicine. Hosted by Michael Neuberger)

2012-05-04 13:00: Transcriptional profiling host responses in Infectious diseases: From HIV infection of macrophages to the tuberculin skin test (Dr Mahdad Noursadeghi, UCL. Hosted by Andres Floto)

2012-05-11 13:00: "The BLIMP-1 regulatory network and models of plasma cell differentiation" (Dr Gina Doody, Leeds Institute of Molecular Medicine. Hosted by Martin Turner)

2012-05-11 16:00: Immune cell transdifferentiation (Thomas Graf, Centre for Genomic Regulation (Barcelona))

2012-05-18 13:00: "Spatio-temporal regulation of antigen presentation and cell migration" (Dr Ana-Maria Lennon-Duménil, Institute Curie, Paris. Hosted by Marion Espeli)

2012-05-21 16:00: Enhancing immune responses by targeting vaccine antigens to Clec9A on dendritic cells" (Professor Ken Shortman, The Walter and Eliza Hall Institute, Australia. Host tbc)

2012-05-25 13:00: "Mesenchymal and haemopoietic stroma: a crucial liaison" (Professor Francesco Dazzi, Chair in Stem Cell Biology and Head of Stem Cell Biology, Dept of Medicine, Imperial College London. Hosted by John Todd)

2012-06-01 13:00: "The cancer macroenvironment modulates adaptive immunity against cancer" (Dr Vincenzo Bronte, Instituto Oncologico Veneto, Padua, Italy. Hosted by Doug Fearon)

2012-06-08 13:00: "Bad blood between the ribosomal subunits" (Professor Alan Warren, University Department of Haematology and MRC-LMB. Hosted by Michael Neuberger)

2012-06-12 15:00: "Taking Advantage: Exploring Darwinian Selection in the Germinal Center" (Dr Mark Shlomchik, Yale School of Medicine. Hosted by Ken Smith)

2012-06-15 13:00: "Epithelial regulation of intestinal inflammation" (Professor Manolis Pasparakis, CECAD, Cologne. Hosted by Arthur Kaser)

2012-06-18 16:00: “Accelerated vaccine and immunotherapy discovery and development: case studies in infectious diseases and cancer" (Dr Mark Poznansky, Massachusetts General Hospital. Hosted by Andrew Lever)

2012-06-22 13:00: “Cell Entry and Innate Immune Recognition of enveloped RNA Viruses” (Dr Yorgo Modis, Yale University. Hosted by Ken Smith)

2012-06-29 13:00: Fueling the fires within: TNF-family receptors in autoimmunity and autoinflammation (Dr Richard Siegel, National Institute of Arthritis and Musculoskeletal & Skin Diseases, NIH. Hosted by Menna Clatworthy)

2012-07-06 13:00: "Regulating T cells in autoimmune and allergic disease" (Professor Stephen M Anderton, MRC Centre for Inflammation Research, University of Edinburgh. Hosted by Andrew McKenzie)

2012-07-13 13:00: CD45 and TIM-1: unique targets for induction of regulatory T and B cells in transplant tolerance" (Professor David Rothstein, University of Pittsburgh. Hosted by Chris Rudd)

2012-07-30 13:00: "Microbial versus Metabolic Inflammation: Fine-tuning Inflammasomes via a GTPase" (Dr Avinash Shenoy, Yale School of Medicine. Host tbc)

2012-09-14 13:00: Microbial versus metabolic inflammation: fine-tuning inflammasomes via a GTPase (Dr Avinash Shenoy, Yale School of Medicine. Hosted by Ken Smith)

2012-09-21 13:00: IFN-inducible GTPases and the art of self defense (John MacMicking, Yale University School of Medicine. Hosted by Felix Randow)

2012-09-28 13:00: " Not all Foxp3+ Regulatory T cells cells are made equal- miRNA-mediated regulation of specialisation" (Dr Mark Wilson, NIMR. Hosted by Michelle Linterman)

2012-10-05 13:00: New insights into bone marrow biology (Professor Sara Rankin, Imperial College London. Hosted by Edwin Chilvers)

2012-10-08 13:00: Adventures in Viral Immunology: Translating DRiPs  (Professor Jon Yewdell, NIAID. Hosted by Paul Lehner)

2012-10-12 13:00: "High resolution gene expression profiling of TNA synthesis, processing and decay" (Lars Dolken, Dept of Medicine. Hosted by Paul Lyons)

2012-10-15 16:00: Tet proteins and methylcytosine oxidation (Anjana Rao, La Jolla Institute for Allergy and Immunology)

2012-10-19 14:30: "Principles of dynamic gene regulation in mammals" (D. Ido Amit, Weizman Institute, Israel. Hosted by Sarah Teichman)

2012-10-19 16:00: Genome-wide mapping of DNA rearrangements in single cells using DNA template strand sequencing (Peter Lansdorp, European Research Institute on the Biology of Ageing, University of Groningen)

2012-10-26 13:00: “Manipulating the dynamics of ubiquitin and histones in cells to create new antigens for MHC class I antigen presentation” (Jacques Neefjes, The Netherlands Cancer Institute, Amsterdam. Hosted by Paul Lehner)

2012-10-30 13:00: The Aging of Hematopoietic Stem Cells (David Bryder, Lund University)

2012-11-02 13:00: "The FAP+ Stromal Cell and a Hierarchy of Tumour Immune Suppression." (Doug Fearon, CRUK. Hosted by John Trowsdale)

2012-11-06 12:00: Signalling Networks in Cell Proliferation and Fate Control (Professor Sibylle Mittnacht, UCL Cancer Institute)

2012-11-09 13:00: "ADARs and innate immunity" (Mary O'Connell, MRC, Human Genetics Unit, Edinburgh. Hosted by Felix Randow)

2012-11-16 13:00: "Preclinical and Clinical Studies of Immunotherapy in Type 1 Diabetes" (Dr Frank Wadron-Lynch, JDRF/WT Diabetes & Inflammation Lab, CIMR. Hosted by Linda Wicker)

2012-11-23 13:00: "Global Progress in TB Vaccine Development" (Professor Helen McShane, University of Oxford. Hosted by Andres Floto)

2012-11-30 13:00: "Targeting T cells for immune staging and intervention in type 1 diabetes" (Dr Roberto Mallone, Hôtel Dieu Hospital. Hosted by John Todd)

2012-11-30 16:00: Epigenetic reprogramming in mammalian development (Wolf Reik)

2012-12-04 12:00: Localisation-based feedback controls during mitosis and the maintenance of chromosomal stability (Dr Adrian Saurin, University Medical Center Utrecht, The Netherlands)

2012-12-07 13:00: "Innate immune signals in splenic and intestinal homeostasis" (Andrea Cerutti. ICREA, Bacelona. Hosted by Michael Neuberger)

2013-02-05 12:00: Telomeres and the challenges to chromosome integrity (Dr Julie Cooper, London Research Institute)

2013-04-26 16:00: Jobs in Science Seminars at the CIMR (Various Speakers - panel discussion, see abstract)

2013-05-03 11:00: Polycomb-mediated selfrenewal of young (and aged?) hematopoietic stem cells (Gerald de Haan, Scientific Co-Director, European Research Institute for the Biology of Ageing)

2013-05-07 12:00: Macrophages Into Tumor Hypoxic Areas: Should I Stay Or Should I Go? (Dr Massimiliano Mazzone, VIB Vesalius Research Center, Belgium)

2013-06-04 12:00: Control of cytokinesis and the dark side of actomyosin forces (Dr Mark Petronczki, London Research Institute)

2013-07-02 13:00: Genetic modifiers and microenvironmental control of tumor invasiveness (Prof Douglas Hanahan, EPFL, Switzerland )

2013-09-03 12:00: Insights  for the role of  tumour-related inflammation and stem cells in Drosophila (Dr Marcos Vidal, Beatson Institute, Glasgow )

2013-09-18 11:00: Look Beyond the Target: How Lessons from Chronic Myeloid Leukaemia Can Improve Cancer Targeted Therapies  (Assoc. Prof. Sin Tiong Ong, Duke-NUS Graduate Medical School Singapore & Duke University Medical Center)

2013-09-20 16:00: Molecular and cellular basis of disease initiation in myeloproliferative neoplasms (Prof. Radek Skoda, Head of the Department of Biomedicine, University Hospital, Basel)

2013-10-07 17:00: Forward genetic screening using patient CML cells identifies IKAROS as a myeloid tumour suppressor (Dr Philip Beer, Terry Fox Laboratory, Vancouver)

2013-10-15 16:00: Mutations in Epigenetic Modifiers in Myeloid Malignancies (Dr Ross Levine, Memorial Sloan-Kettering Cancer Center, New York)

2013-10-18 16:00: Bone marrow environment and platelet production (Assoc. Prof. Alessandra Balduini, University of Pavia Italy, and Tufts University USA)

2013-11-08 16:00: Emerging therapeutic strategies for treating the first molecular disease (Prof. James Douglas Engel, University of Michigan Medical School, USA)

2013-11-12 12:30: Haematopoietic Stem Cells (Prof. Connie Eaves, Terry Fox Laboratory, Vancouver)

2013-11-22 16:00: Cancer Epigenetics: Appreciating the beauty and complexity of a string of pearls (Mark Dawson, University of Cambridge)

2013-12-03 12:00: The autophagy signaling network in the coordination of a cell's response (Prof Francesco Cecconi, University of Tor Vergata, Italy )

2014-01-07 12:00: Chasing metabolic alterations in cancer (Dr Arkaitz Carracedo, CIC bioGUNE,  (Center for Cooperative Research in Biosciences), Derio, Spain)

2014-01-07 16:00: Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology (Bengt Hallberg (Umea University, Sweden))

2014-01-17 13:00: SerenDRiPity: Translating DRiPs for T Cell Immunosurveillance of Tumors and Viruses (Jon Yewdell)

2014-01-31 13:00: T cell migration in tumors: a role for matrix architecture (Emmanuel Donnadieu, INSERM, PAris)

2014-02-04 12:00: Translating Tumour Metabolism into New Diagnostics and Novel Anti-Cancer Therapeutics (Professor Michael Lisanti, Director of the Breakthrough Breast Cancer Research Unit, University of Manchester)

2014-02-07 16:00: 4D tracking of haematopoietic stem and progenitor cells in their bone marrow microenvironment (Dr Cristina Lo Celso, Imperial College London)

2014-02-14 13:00: Enhancing the CD8 T cell response by RAE-1 gamma expressed in a herpesvirus vector – not only NKG2D (Stipan Jonjic,  Rijeka, Croatia)

2014-02-28 13:00: Prevention of immune pathology by specialized regulatory cell subsets (Luis Graca, Universidade de Lisboa)

2014-03-04 12:00: Cell death and autophagy in response to inhibition of glycolysis (Dr Cristina Muñoz Pinedo, IDIBELL, Barcelona, Spain)

2014-03-07 13:00: Notch and Wnt Signaling: From Hematopoeitic Stem Cells to Leukemia (Anna Bigas. Cancer and Stem Cells Research Group. Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

2014-03-13 14:30: Host-pathogen interactions: a biochemist's perspective (Hidde Ploegh,  Whitehead Institute)

2014-03-14 11:00: Of mice and men and Tasmanian devils; assembling reference genomes from single cells. (Dr Mark Hills, Terry Fox Lab, Vancouver, Canada)

2014-03-14 13:00: HPV vaccines where to next? (Professor Margaret Stanley, Department of Pathology)

2014-03-21 16:00: Heterogeneity of hematopoietic stem and progenitor cell populations: implications for ageing and regeneration (Claus Nerlov, University of Oxford)

2014-04-04 16:00: Neuroendocrine regulation of the bone marrow stem-cell niche (Simón Méndez-Ferrer, CNIC, Madrid, Spain)

2014-04-08 12:00: Targeting bioenergetics in hypoxic and rapidly growing tumours (Dr Jacques Pouysseggur, Institute of Research on Cancer and Ageing (IRCAN), Nice, France)

2014-04-22 15:00: Engaging mechanisms of negative B cell selection to overcome drug-resistance in leukaemia (Prof. Markus Müschen, UCSF)

2014-05-02 13:00: Stromal cell regulation of lymph node structure and function (Alice Denton, CRUK)

2014-05-06 12:00: Spatio-temporal control of RhoGTPases and the cytoskeleton in invading cancer cells by integrins and endocytic trafficking (Dr Patrick Caswell, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester)

2014-05-13 16:00: Familial thrombocytopenias with predisposition to leukemia: RUNX1 targets (Dr Hana Raslova, Institut Gustave Roussy, Paris)

2014-05-14 10:30: Title to be confirmed (Wenjun Ouyang)

2014-05-16 13:00: Targeting host endomembrane integrity during cellular invasion by bacterial pathogens and its impact on the immune response (Jost Enninga, Institut Pasteur)

2014-05-23 10:30: IL-22 and NRROS in host defense and inflammation (Wenjun Ouyang, Genentech)

2014-05-23 13:00: Models of the germinal centre reaction (Michael Meyer-Hermann, Helmholtz Centre for Infection Research)

2014-05-30 13:00: HIV-1 Infection, Type-1 Interferon and Viral Restriction (Michael Malim, King's College London)

2014-06-03 12:00: Undermining Myc: Mitochondria Hold the Key (Dr Daniel Murphy, Institute of Cancer Sciences, University of Glasgow)

2014-06-06 16:00: Regulation of Akt by the Sin1-mTOR complex in lymphocytes (Prof. Bing Su (Department of Immunobiology at Yale, and Shanghai Institute of Immunology at Shanghai JiaoTong University School of Medicine))

2014-06-13 13:00: Diversity of mouse B cell memory subsets (Claude-Agnès Reynaud, INSERM)

2014-06-27 13:00: PI3K in Immunity, Infection and Cancer (Klaus Okkenhaug, Babraham Institute)

2014-07-02 16:15: Normal and leukaemic (AML) human stem/progenitor cells (Prof. Paresh Vyas, WIMM, Oxford University)

2014-07-14 16:00: Targeting survival pathways in CML stem cell persistence and TKI-resistance (Prof. Tessa Holyoake, University of Glasgow)

2014-09-08 16:00: Aurora A kinase and RPS14: new players in the myeloproliferative neoplasms (Prof. John Crispino, Northwestern University, Chicago)

2014-09-11 13:00: Illuminating the microanatomical positioning and function of dendritic cells in vivo (Michael Gerner, National Institute of Allergy and Infectious Disease, Bethesda)

2014-09-19 16:00: Clinical and Biological Impact of Flt3 mutations in Acute Leukaemia (Dr Adam Mead, University of Oxford)

2014-10-03 13:00: Understanding & Exploiting the NKT cell:CD1d System in Cancer and Other Diseases (Mark Exley, Manchester Collaborative Centre for Inflammation Research (MCCIR))

2014-10-07 12:00: The role of stem cells in the pathogenesis of hepato-biliary cancers (Professor Nisar Malek, University of Tubingen, Germany)

2014-10-16 16:00: Hematopoietic stem cell formation in the embryo (Prof. Nancy Speck, University of Pennsylvania)

2014-10-17 13:00: Multiscale imaging of cell entry and innate immune recognition of enveloped RNA viruses (Yorgo Modis, Department of Medicine)

2014-10-31 13:00: Leukocyte migration and gradient sensing in vivo: lessons from zebrafish (Milka Sarris, Department of Physiology, Development and Neuroscience)

2014-11-14 13:00: Designing vaccines: genetics of T follicular helper cells (Tfh) (Shane Crotty, La Jolla Institute)

2014-11-14 16:00: Mimicking of the process of human erythropoiesis using in vitro culture; studies on red blood cell membrane assembly and also use of 3D scaffolds (Dr Ashley Toye, University of Bristol)

2014-11-19 12:00: Cell fate in response to anti-mitotic chemotherapeutics (Professor Stephen Taylor, Faculty of Life Sciences, University of Manchester)

2014-11-28 13:00: Lymphocyte population dynamics and genetic susceptibility to autoimmune  disease (Rose Zamoyska, University of Edinburgh)

2014-12-02 12:00: In vivo function-based genomic approaches for cancer drug target discovery  (Professor Daniel Peeper, Head, Division of Molecular Oncology, The Netherlands Cancer Institute)

2014-12-12 13:00: Mechanisms of immune-metabolic interaction in infection (Marc Dionne,  King's College London)

2015-01-09 13:00: The Abnormalities in Plasma Cells in an Autoimmmune Disease Provide both a Window and a Key ( David Tarlinton, WEHI, Melbourne )

2015-01-23 13:00: Generating Immunity to an Immunosupressive Virus: The HIV Vaccine Conundrum (Prof. Jonathan Heeney (University of Cambridge))

2015-02-03 12:00: MYC Oncoproteins act as Epigenetic Modifiers (Dr Frank Westermann, Research Group Neuroblastoma Genomics, DKFZ, Heidelberg)

2015-02-06 13:00: Novel functions for IgG in modulating immune highways and DC trafficking (Dr Menna Clatworthy (University of Cambridge))

2015-02-11 10:00: Predictive Engineering of Cell Fate (Prof. Peter Zandstra, University of Toronto)

2015-02-20 13:00: Improved mismatched cell transplants for cancer immunotherapy (Dr Francesco Colucci (University of Cambridge))

2015-03-03 12:00: Systems Biology of Cancer (Professor Jussi Taipale, Department of Biosciences and Nutrition, Karolinska Institute, Sweden )

2015-03-06 13:00: Environmental sensing by blood cells (Henrique Veiga-Fernandes, Instituto de Medicina Molecular, Lisbon.)

2015-03-20 13:00: Mechanical forces in B cell activation (Pavel Tolar, MRC National Institute for Medical Research, Mill Hill)

2015-03-20 16:00: Aberrant chromatin programming in AML (Prof. Constanze Bonifer, University of Birmingham)

2015-04-10 13:00: Innate Lymphoid Cells: New Players in Immune Defense and Tissue Homeostasis (James Di Santo, Institut Pasteur)

2015-04-24 13:00: Immune evasion by the meningococcus: the competition hots up (Chris Tang, Oxford)

2015-05-05 12:00: Metastatic Stem Cells, TGF-beta signalling and poor-prognosis in CRC (Dr Eduard Batlle (Group Leader, Institute for Research in Biomedicine, Barcelona))

2015-05-08 13:00: Tissue-resident memory T cells and role of antibodies in the LCMV  model (Hanspeter Pircher, Institute of Immunology, Freiburg)

2015-05-08 16:00: Title to be confirmed (Prof. Frederic Geissman, Kings College London)

2015-05-19 12:00: DNA damage response: Mechanisms and relevance for cancer development and treatment (Professor Jiri Bartek, The Danish Cancer Society Research Center Genome Integrity Unit, Denmark)

2015-05-20 13:00: Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis (Dr Nina Cabezas (DKFZ, Heidelberg))

2015-06-02 12:00: 'ECM remodelling during cancer progression' (Dr Janine Erler, Associate Professor - Biotech Research & Innovation Centre (BRIC),Copenhagen )

2015-06-05 16:00: Making Hematopoietic Stem Cells: Backwards and Sideways (Dr Derrick Rossi (Harvard, USA))

2015-06-17 11:00: Insights into mammalian hematopoiesis from comparative functional genomic (Prof. Ross Hardison (Penn State))

2015-06-19 13:00: Human and mouse mononuclear phagocyte networks: a tale of two species? (Muzlifah Haniffa Newcastle)

2015-07-03 13:00: The role of cystine-knot proteins in vertebrate immunity to Staphylococcus aureus  (Dr Andres Floto (University of Cambridge))

2015-07-07 11:00: ‘Novel dual-action combination therapy enhances angiogenesis whilst reducing tumour growth and spread’ (Professor Kairbaan Hodivala-Dilke, Professor of Angiogenesis, Deputy Institute Director QMUL )

2015-09-11 13:00: "Dendritic cells in the initiation of immunity to infection and cancer" (Caetano Reis e Sousa, Cancer Research UK London Research Institute)

2015-09-14 14:00: Taming the enemy within-host-epithelial interactions in the intestinal tract (Philip Rosenstiel, University of Kiel)

2015-09-25 13:00: “In Situ Signatures of Apoptotic Cell Recognition” (Julie Blander, Icahn School of Medicine, NewYork)

2015-10-09 13:00: "Investigating the pathogenesis and developing new therapies for Respiratory Disease" (Phil Hansbro, The University of Newcastle, Australia)

2015-10-14 15:00: ‘A tale of cities; the differing challenges of antimicrobial resistance in Ho Chi Minh City and Kathmandu’ (Stephen Baker)

2015-10-23 13:00: "Programming Humoural Immune Responses" (Ed Clark, University of Washington)

2015-11-06 13:00: "Pathways that target PD-1 and the nuclear pore complex (NPC) in cancer immunotherapy" (Christopher Rudd, Cambridge)

2015-11-17 11:30: Intrinsic and extrinsic determinants of pancreatic cancer stem cells (Professor Christopher Heeschen, Centre Lead, Centre for Stem Cells in Cancer and Ageing, Barts Cancer Institute, London)

2015-11-19 11:00: "A close up view on T cell mechanisms in  autoimmunity : dissecting childhood arthritis" (Lucy Wedderburn, UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust )

2015-12-04 13:00: “Mobile elements, polydactyl proteins and the species-specificity of human biology” (Didier Trono, Ecole Polytechnique Fédérale de Lausanne, Switzerland)

2016-01-15 13:00: "Disturbed PI3K signalling as cause for primary immune deficiency disease" (Sven Kracker)

2016-01-18 16:00: Sub-clonal heterogeneity in chronic myeloid leukemia (Mike Schmitt - Fred Hutchinson Cancer Research Centre, University of Washington)

2016-01-20 16:30: Placing BETs on hold in AML (Mark Dawson - Peter MacCallum Cancer Centre, Melbourne, Australia)

2016-01-29 13:00: "The human immune system is maintained in multiple stable equilibriums shaped by age and cohabitation" (Michelle Linterman)

2016-02-12 13:00: "The impact of immunogenetic variation on human disease” (Mary Carrington, NIH, US)

2016-02-26 13:00: "Mechanisms and Pathways of microbe-host crosstalk in the GI tract" (Simon Carding, IFR Norwich)

2016-03-08 10:00: Single-cell analysis of hematopoietic stem cell identity and behaviour (David Knapp -- Terry Fox Laboratory, Vancouver)

2016-03-11 13:00: "Tracking down antigen specific T and B cells to dissect autoimmunity" (Ludvig Sollid,, University of Oslo.)

2016-04-18 13:00: The Case Of The Missing Ribosomes: A Translational Mystery (Jon Yewdell,  from NIH)

2016-04-22 13:00: TGF-beta signaling in ILC3 prevents spontaneous microbiota-induced colorectal cancer (Julien Marie, CRCL, Lyon)

2016-05-03 11:30: “Mechanisms of MYC-driven genome instability” (Jean Gautier, Professor of Genetic and Development, Institute for Cancer Genetics, Columbia University, New York (USA))

2016-05-06 13:00: T-cell differentiation in chronic infection – functional adaptation or exhaustion? (Dietmar Zehn CHUV, Switzerland)

2016-05-20 13:00: "MicroRNA-mediated regulation of T follicular helper and Th17 cells" (Dirk Baumjohann, Biomedical Centre, Munich)

2016-05-27 13:00: “Oh, to be seventeen again: IL-17 receptor signaling in fungal immunity and autoimmunity” (Sarah Gaffen, University of Pittsburgh)

2016-06-03 13:00: Restriction of zoonotic viruses by bat Interferon-Induced Transmembrane Proteins (Camilla Benfield, RVC, London)

2016-06-17 13:00: “Multiple levels of control for E4bp4/Nfil3 in NK cell development” (Hugh Brady,  Imperial)

2016-07-05 11:30: "Mechanisms of colon cancer initiation, progression and metastasis" (Joerg Huelsken, Associate Professor, Debiopharm Chair in Signal Transduction in Oncogenesis, EPFL, Lausanne)

2016-07-29 13:00:  “A Force from within: Unexpected roles for innate immunity in intrinsic Th1 regulation"  (Claudia Kemper, King’s College London)

2016-08-30 12:00: Voltage-gated proton channels influence BCR signalling in normal and malignant B cells (Melania Capasso, Barts Cancer Institute)

2016-09-09 12:00: Voltage-gated proton channels influence BCR signalling in normal and malignant B cells (Melania Capasso, Barts Cancer Institute)

2016-10-07 13:00: "IL-33 and Alzheimer’s disease" (Foo (Eddy) Liew,  University of Glasgow)

2016-10-14 13:00: "Systemic inflammation negatively affects neurodegenerative disease: Priming of microglia and astrocytes at the interface of dementia and delirium" (Dr Colm Cunningham, Trinity College Dublin)

2016-10-14 14:30: Structure vs. Function: A quantitative analysis of chromosome architecture (Luca Giorgetti - Friedrich Miescher Institute, Basel)

2016-10-21 13:00: “B cell selection in germinal centres” (Kai Toellner, Birmingham University)

2016-11-04 13:00: Epigenetics and genome plasticity in the human fungal pathogen Candida albicans (Alessia Buscaino, University of Kent)

2016-11-17 11:00: Elucidation of oncogenic B cell receptor signaling (Thomas Oellerich Department of Haematology, Cambridge Institute of Medical Research / Department of Medicine II, Haematology/Oncology, Goethe University Frankfurt)

2016-11-18 13:00: "TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis" (Christoph Mueller, University of Bern)

2016-11-25 13:00: “How oncogenes reprogramme inflammation” (Gerard Evan, University of Cambridge)

2016-12-02 13:00: Disease models & droplet-microfluidics to understand IgG antibody biology (Pierre Bruhns, Institut Pasteur)

2016-12-12 13:00: Mitochondria-associated ER membranes are immunometabolic hubs that orchestrate the rapid recall response of CD8 T cells (Christoph Hess)

2017-01-20 13:00: From Cellular Microbiology to Cell Physics investigating host cell response to infection (Frank Lafont, Institut Pasteur)

2017-02-03 13:00: "New insights into the mechanisms controlling MHC class I peptide selection" (Louise Boyle, University of Cambridge)

2017-02-07 11:30: The interaction between tumor hypoxia and DNA methylation  (Dr Bernard Thienpont, VIB-KU Leuven Center for Cancer Biology, KU Leuven, Belgium)

2017-02-17 13:00: “Infection, Inflammasomes and Autophagy” (Tom Evans, University of Glasgow)

2017-02-21 11:00: "Food poisoning, Salmonella and their molecular contribution to gallbladder and colon cancer" (Jacques Neefjes, Netherlands Cancer Institute)

2017-03-03 13:00: "Calcineurin and the microbiota in intestinal tumor development" (Sebastian Zeissig, Center for Regenerative Therapies Dresden)

2017-03-07 11:30: ‘Non-coding RNA - new roles for old players’ (Professor Anders Lund, Biotech Research and Innovation Centre, University of Copenhagen)

2017-03-09 11:00: The modulation of CD44 isoforms by the spleen microenvironment in CLL (Tanja Hartmann; Salzburg Cancer Research Institute)

2017-04-13 12:00: Pancreatic Cancer: Cachexia, Systemic Metabolism, Immunity and Occult Metastases (Douglas Fearon, Cold Spring Harbor Laboratory)

2017-05-02 11:30: ‘Alterations of the Polycomb machinery in cancers’ (Raphaël Margueron, Curie Institute, Paris)

2017-05-25 15:00: 'Analyses for Rule-Based Models of Cellular Signalling' (Dr Jean Yang, Assistant Professor,Department of Computer Science, Carnegie Mellon University, Pittsburgh USA )

2017-06-06 11:30: ‘Exploring and exploiting aberrant self-fate programs in leukemia’ (Dr Johannes Zuber, Research Institute of Molecular Pathology (IMP), Vienna, Austria)

2017-06-16 13:00: Nucleation, Heritability and Dynamics of Specialized Chromatin Domains (Robin Allshire, University of Edinburgh)

2017-06-30 13:00: "Lung epithelia under attack: influenza, interferons and pollutants” (Andreas Wack, Crick Institute)

2017-09-18 14:00: ‘The role of Mre11 in DNA double strand break repair  -  myth and facts’ (Professor Shunichi Takeda, Department of Radiation Genetics, Kyoto University)

2017-09-29 13:00: Navigating the ILC Transcriptional Landscape (Gabrielle Belz, WEHI)

2017-10-17 11:00: "Function of the B-cell receptor in malignancies” (Prof Graham Packham, )

2017-10-27 13:00: "Developing new immune therapies to treat Type 1 diabetes" (Frank Waldron-Lynch, University of Cambridge)

2017-11-07 11:30: Metastasis latency: new molecular insights (Roger Gomis, ICREA Research Professor, IRB Barcelona)

2017-11-10 13:00: “Manipulating T cell signalling to improve anti-tumour immunity” (Robert Salmond, Leeds Institute of Cancer and Pathology)

2017-11-23 11:00: Function of the B-cell receptor in malignancies (Prof Graham Packham)

2017-11-27 11:00: Engineering therapeutic T cells (Dr Sara Ghorashian)

2017-12-05 11:30: ‘Tracking metabolic reprogramming in cancers with PI3K/Akt activation’ (George Poulogiannis, Team Leader, Division of Cancer Biology, Institute of Cancer Research, London)

2018-02-02 13:00: Regulation of neutrophil function by the interplay between oxygen and metabolite sensing pathways  (Sarah Walmsley, THE UNIVERSITY OF EDINBURGH)

2018-02-16 13:00: “A cellular response pathway to viroporin induced aberrant neutrality” (Rupert Beale, University of Cambridge)

2018-03-02 13:00: Structure and function of retroviral integrase (Peter Cherepanov, The Francis Crick Institute)

2018-03-06 11:30: ‘Instituting Molecular Precision in Localised Prostate Cancer - A Cure for All?’ (Rob Bristow, University Professor of Cancer Studies, Director of MCRC)

2018-03-08 16:00: "Genomic control mechanisms that establish T-cell identity” (Ellen Rothenberg, CalTech)

2018-05-03 11:00: ‘Accelerating the translation of mutational signatures' (Dr Serena Nik-Zainal, Wellcome Sanger Institute)

2018-05-11 13:00: "The ZFP36-family of RNA Binding Proteins are regulators  of lymphocyte activation and differentiation'' (Martin Turner, Babraham Institute)

2018-05-25 13:00: “Novel signalling pathways controlling T cell adhesion and migration” (Victor Tybulewicz, Francis Crick Institute)

2018-06-05 11:00: ‘Cellular Plasticity in Cancer:  driving force and therapeutic target’ (Professor Thomas Brabletz, Department of Experimental Medicine, University Erlangen-Nuernberg)

2018-06-15 10:30: ‘Nuclear Mechanopathology & Early Cancer Diagnostics’ (Professor GS Shivashankar, Deputy Director, Mechanobiology Institute, National University of Singapore)

2018-06-21 12:00: ‘Fetal tolerance and anti-viral immunity at the maternal-fetal interface in human pregnancy’ (Tamara Tilburgs, Harvard University)

2018-06-22 13:00: "Understanding diversity in the human immune system" (Adrian Liston, Univ. of Leuven)

2018-07-13 13:00: “Kaposi Sarcoma Herpesvirus Latent Nuclear Antigen (LANA): multiple facets of latent replication” (Thomas Schulz, Medizinische Hochschule Hannover)

2018-09-28 13:00: Reconstructing the human maternal-fetal interface during early pregnancy using single cell transcriptomics (Roser Vento-Tormo, Sanger Institute)

2018-10-19 13:00: “ A  powerful methodology for detecting health consequences from any treatment: test cases of suspected toxins, mutations, MHC, pharmaceuticals and diet” (Wayne Potts, University of Utah)

2018-10-26 13:00: Generating data-informed cellular consensus maps as exemplified for the human myeloid cell compartment (Joachim Schultze, University of Bonn)

2018-11-08 13:00: "Activation of T cells is under mechanical control" (Marco Fritzsche, The Weatherall Institute of Molecular Medicine University of Oxford)

2018-12-04 11:30: ‘Executable Disease Networks: Reconstruction, Topology, Dynamics’ (Anna Niarakis, Université Paris-Saclay, Evry, France)

2019-01-15 11:30: THIS SEMIAR IS NOW CANCELLED  -                                                            'Cell Plasticity in Colon Carcinogenesis' (Professor Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frankfurt)

2019-04-09 11:30: ‘Mammary epithelial cell fate and tumour initiation at the single cell resolution’ (Walid Khaled, Department of Pharmacology, University of Cambridge)

2019-05-07 11:30: ‘New protagonists of the tumour microenvironment’ (Dr Ilaria Malanchi, Tumour-Host Interaction Lab,Francis Crick Institute, London )

2019-06-11 11:30: ‘Next-Generation Biopsies in Gastrointestinal Cancers’ (Dr Nicola Valeri, Institute of Cancer Research and The Royal Marsden NHS Trust)

2019-07-01 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Institute for Tumor Biology and Experimental Therapy Frankfurt)

2019-07-10 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Heidelberg University, Faculty of Medicine & EMBL- Heidelberg University Molecular Medicine Partnership Unit)

2019-09-03 11:30: ‘Treatment of cancer by inhibition of mtDNA gene expression’ (Nils-Göran Larsson, MD, PhD, Professor, Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm )

2019-10-01 11:30:  ‘Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis’ (Professor Albena Dinkova-Kostova,Jacqui Wood Cancer Centre, Division of Cellular Medicine, University of Dundee  )

2019-12-03 11:30: ‘Cell Plasticity in Colon Carcinogenesis’ (Professor Dr Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frakfurt)

2020-04-07 11:30: CANCELLED - “Cancer genomics: from chromatin structure to new therapeutic targets” (Professor Elisa Oricchio (EPFL, Zurich))