Department of Biochemistry, Sanger Building Jean Thomas Lecture Theatre


2017-08-31 14:00: Prof. Nieng Yan - Title tbc (Prof. Nieng Yan)

2017-10-17 13:00: 	 Understanding the molecular mechanisms of neuropilin signalling – implications for intervention (Dr Snezana Djordjevic)

2017-10-20 17:00: Sanger Distinguished Lecture 2017, Sanger’s Legacy – Using High Throughput Human Exome Sequencing with Mouse Genome Engineering to Guide Discovery and Medicine (Neil Stahl)

2017-10-24 13:00: Stress, Translation and mRNA localisation: Messages that play together stick together (Prof Mark Ashe )

2017-10-31 13:00: Targeting the Drosophila X chromosome for global transcription regulation (Prof. Peter Becker)

2017-11-07 13:00: Actin-myosin cytoskeleton regulation in cell migration and tissue homeostasis (Prof. Mike Olsen)

2017-11-14 13:00: DNA Protein Crosslink  Proteolysis Repair (Kristijan Ramadan)

2017-11-20 17:00: Genome-wide analysis of protein-DNA interactions (Professor Jussi Taipale, Herchel Smith Professor of Biochemistry)

2017-11-21 13:00: The sweet and sour attraction of microbes to mucin: a biochemical and structural perspective (Dr. Nathalie Juge)

2017-11-28 13:00: Cryo-EM structures of tau filaments from Alzheimer's disease (Dr. Sjors Sheres)

2017-12-05 14:00: Horizon’s Adventures in CRISPR land (Dr Nicola McCarthy)

2018-01-16 13:00: CANCELLED: Getting in Shape: in vivo and in silico studies of tissue mechanics in growth control (Dr. Yanlan Mao)

2018-01-23 13:00: Structural insights into severe malaria (Prof. Matt Higgins)

2018-01-30 13:00: The glycobiology of antibodies, Fc receptors and the immune response (Jerrard Hayes)

2018-02-06 13:00: Determining structures in situ using cryo-electron tomography:enveloped viruses and coated vesicles (Dr. John Briggs)

2018-02-13 13:00: Description: TIE proteins: chemical harpoons of Gram-positive bacteria (Dr. Ulrich Schwarz-Linek )

2018-02-20 13:00: Feeding your genes: The impact of nitrogen availability on gene and genome sequence evolution (Prof. Steve Kelly)

2018-02-27 14:15:  DISCOVERY AND QUALIFICATION OF CANDIDATE URINARY BIOMARKERS OF DISEASE ACTIVITY IN LUPUS NEPHRITIS  (Dr. Veronica Anania from Genentech, South San Francisco, CA, USA)

2018-02-27 17:00: The Hopkins Lecture 2018 - mTOR and Lysosomes in Growth Control (Dr David Sabatini - Massachusetts Institute of Technology)

2018-03-06 13:00:  “Structural Biology and Chemistry of Histone Deacetylases in Human Disease and Drug Discover (Prof. David Christianson)

2018-03-13 13:00: Transcription by influenza virus RNA polymerase: molecular mechanisms, cellular aspects and inhibition (Prof. Stephen Cusack)

2018-04-24 13:00: Description: Olfaction of biologically relevant vapors by secondary electrospray ionization mass spectrometry (Dr Pablo Martinez-Lozano Sinues)

2018-05-18 16:00: From its origins to the modern metabolic network (Dr Markus Ralser, Francis Crick Institute)

2018-06-04 14:00: “TissueFAXS Cytometry - A Tool for Precision Medicine: Automated Analysis of Single Cells and the Cellular Microenvironment” (Dr Rupert Ecker CEO TissueGnostics GmbH)

2018-09-03 11:00: Cryo-EM structure of an insecticidal toxin–ion channel complex reveals the complex molecular basis of allosteric modulation of channel gating (Prof. Glenn King (University of Queensland, Australia))

2018-10-15 17:00: Alkis Seraphim Lecture 2018 - PI 3-Kinase and Cancer Metabolism (Dr Lew Cantley)

2018-10-16 13:00: Fuzzy Protein Theory (Professor Monika Fuxreiter)

2018-10-23 13:00: Polarized endosome dynamics during asymmetric cell division (Dr Emmanuel Derivery)

2018-10-30 13:00: Multivalent interactions as a source of specificity and regulation in RNP assembly (Professor Jernej Ule)

2018-11-06 13:00: CANCELLED: Mycobacterial structural biology and prospects for drug development in academia CANCELLED (Dr Lionel Mourey )

2018-11-09 13:00: Cell Death, Inflammation and the defence of Tissue Homeostasis (Dr. Pascal Meier)

2018-11-13 13:00:  Cell signalling by receptor tyrosine phosphatases (Dr Hayley Sharpe)

2018-11-16 15:30: Biochemistry Friday Seminars (Dr Ross Waller, Department of Biochemistry, University of Cambridge)

2018-11-20 13:00: Description: A good Aβ? Bioinorganic perspective on the toxicity and physiological role of beta-amyloid peptides (Prof Wojcieh Bal )

2018-11-23 15:00: Biochemistry Friday Seminars (Dr Marko Hyvonen, Department of Biochemistry, University of Cambridge)

2018-11-26 17:00: Annual Hopkins Seminar 2018 - Targeted Antisense Therapeutics for Modulation of Splicing or NMD (Professor Adrian R Krainer )

2018-11-30 15:00: Biochemistry Friday Seminars - "Lessons From Dorothy Hodgkin and Insulin in Oxford for Structural Biology, Informatics and New Drugs in Cambridge” (Prof /Sir Tom Blundell, Deparmtent of Biochemistry, University of Cambridge)

2018-12-04 13:00: Insights into the secretion machine of virulence factors in apicomplexan parasites (Dr Maryse Lebrun)

2018-12-07 15:00: Biochemistry Friday Seminars - Imaging tumour metabolism to guide treatment of breast cancer with drugs targeted at PI3K alpha (Susana Ros, Brindle Group, Department of Biochemistry, University of Cambridge)

2018-12-11 13:00: Description:Novel functions of the C-terminal domain of PTCH1: a platform for non-canonical Hedgehog signalling (Dr Natalia Riobo-Del Gardo)

2019-01-11 15:00: Biochemistry Friday Seminars - Looking for microglial therapeutic targets in Alzheimer’s disease (Brown Group, Department of Biochemistry, University of Cambridge)

2019-01-15 13:00: Focused and global methods to characterize protein complex (re)organization in perturbed systems (Dr Ben Collins)

2019-01-18 15:00: Biochemistry Friday Seminars (Dr M de la Roche, Departmentof Biochemistry, University of Cambridge)

2019-01-22 13:00: Description: Structural and Molecular Biology of Bacterial Type 4 Secretion Systems (Professor Gabriel Waksman)

2019-01-25 15:00: Biochemistry Friday Seminars - The plant Golgi apparatus and complex carbohydrate biosynthesis: human health and environmental sustainability. (Professor Paul Dupree, Department of Biochemistry, University of Cambridge)

2019-01-29 13:00: Description: PLK1 inactivation destroys chromosome biorientation through a BLM-mediated centromere disintegration mechanism (Dr Kok-Iung Chan)

2019-02-01 15:00: Biochemistry Friday Seminars - One Billion Years of Evolutionary Solitude (Professor Mark Carrington, Department of Biochemistry, University of Cambridge)

2019-02-05 13:00: Temporal Scaling of C. elegans Ageing (Dr Nicholas Stroustrup)

2019-02-08 15:00: Biochemistry Friday Seminars- Where cancers come from and how to get rid of them (Evan Group, Department of Biochemistry, University of Cambridge)

2019-02-12 13:00: Body temperature controlled kinase activity: from rhythmic alternative splicing in mammals to sex determination in reptiles.  (Professor Florian Heyd)

2019-02-15 13:00:  Human cardiac organoids for fundamental biology and drug discovery applications (Dr James Hudson)

2019-02-15 15:00: Biochemistry Friday Seminars - Collagen - final twists in the tale as we stagger towards the end (Professor Richard Farndale, Department of Biochemistry, University of Cambridge)

2019-02-19 13:00: Protein design to understand natural proteins and to create useful new ones (Professor Lynne Regan)

2019-02-22 15:00: Biochemistry Friday Seminars - Executable Biology:  From Mechanistic Insights to Clinical Applications in Cancer Therapy (Fisher Group, Department of Biochemistry, University of Cambridge)

2019-02-26 13:00: The molecular evolution of C4 photosynthesis (Professor Julian Hibberd)

2019-02-27 11:00: Micro Electron Diffraction in a Cryo Electron Microscope: A powerful tool for protein and small molecule structure determination (Dr Abhay Kotecha, Materials and Structural Analysis Division, Thermo Fisher Scientific, Eindhoven, The Netherlands)

2019-02-28 13:00: Protein synthesis; Which RNAs? Which ribosomes? (Dr Julie Aspden)

2019-03-01 15:00: Biochemistry Friday Seminars - How do proteins build cells? Polymerising actin where and when you want it (Dr Jenny Gallop, Department of Biochemistry, University of Cambridge)

2019-03-05 13:00: Description: Translocation, Translocation, Translocation: Solving the molecular mystery of mycolactone’s cellular target in Buruli ulcer disease (Dr Rachel Simmonds)

2019-03-06 17:00: 3R's Seminar Series - Chromatin Replication and Epigenome Maintenance (Professor Anja Groth (BRIC, University of Copenhagen))

2019-03-08 15:00: Biochemistry Friday Seminars - Harnessing the power of Toll signalling in the fight against mosquito-borne diseases (Dr Monique Gangloff, Department of Biochemistry, University of Cambridge)

2019-03-12 13:00: Evolutionary divergence in the initiation of translation (Dr Yaser Hashem)

2019-03-15 15:00: Biochemistry Friday Seminars - It's the stoichiometry, stupid!  Cooperativity and complexity in the regulation of inflammatory signalling (Gay Group, Department of Biochemistry, University of Cambridge)

2019-03-22 15:00: No Biochemistry Friday Seminar (Speaker to be confirmed)

2019-03-29 15:00: Biochemistry Friday Seminars - Fatty Liver and the Metabolic Syndrome Across Europe (Griffin Group, Department of Biochemistry, University of Cambridge)

2019-04-04 14:00: In vivo protein crystallization: conditions, principles and future perspectives (Professor Michael Duszenko)

2019-04-05 15:00: Biochemistry Friday Seminars -  “Chromatin remodelling, transcription and cell fate: NuRD is the Word” - Brian Hendrich  "NuRD facilitates lineage decisions in human pluripotent cells” - Ramy Ragheb (Dr Brian Hendrich, Department of Biochemistry, University of Cambridge)

2019-04-10 11:00: "Model building, refinement and validation in CCP-EM” ( Dr Colin Palmer, CCP-EM Development Team, Rutherford Appleton Laboratory, Didcot, UK)

2019-04-12 15:00: Biochemistry Friday Seminars - Lost in Sequence Space? Strategies to identify and evolve functional proteins in library experiment (Hollfelder Group, Department of Biochemistry, University of Cambridge)

2019-04-26 15:00: Biochemistry Friday Seminars - The Good, the Bad and the Algae (Professor Chris Howe and Dr Ellen Nisbet, Department of Biochemistry, University of Cambridge)

2019-05-10 15:00: Biochemistry Friday Seminars (Jackson Group, Department of Biochemistry, University of Cambridge)

2019-05-17 15:00: Biochemistry Friday Seminars - bATMan INVESTIGATED (Dr Svetlana Khoronenkova, Department of Biochemistry, University of Cambridge)

2019-05-28 13:00: Multiomics elucidates transcriptional gene regulation (Prof Patrick Cramer)

2019-05-31 15:00: No Biochemistry Seminar (Speaker to be confirmed)

2019-06-07 15:00: Biochemistry Friday Seminars - Fun with Maps......the Dynamic Relocalisation of CCP ........Introducing LoRNA (Professor Kathryn Lilley, Department of Biochemistry, University of Cambridge)

2019-06-10 13:00: MDM2 Splicing Control: a rheostat for p53 activity (Dr Dawn Chandler)

2019-06-14 15:00: Biochemistry Friday Seminars - One Billion Years (and 45 minutes) of Chaos (Luisi Group, Department of Biochemistry, University of Cambridge)

2019-06-21 15:00: Biochemistry Friday Seminars (Dr J Mata - Department of Biochemistry, University of Cambridge)

2019-06-28 15:00: Biochemistry Friday Seminars (Prof S Lummis, Department of Biochemistry, University of Cambridge)

2019-07-05 15:00: Biochemistry Friday Seminars (Dr Paula MacGregor, Department of Biochemistry, University of Cambridge)

2019-07-12 15:00: Biochemistry Friday Seminars - No Seminar (Speaker to be confirmed)

2019-07-19 15:00: Biochemistry Friday Seminars - "Inside the lipid bilayer:  Membranes, Molecules and Magnets" (Dr Daniel Nietlispach, Department of Biochemistry, University of Cambridge)

2019-09-06 15:00: Biochemistry Friday Seminars - Using yeast to model human diseases: parasites to paralysis (Professor Steve Oliver, Department of Biochemistry, University of Cambrige)

2019-09-20 15:00: Biochemistry Friday Seminars -  Macromolecular mechanisms for the replication and maintenance of our genome  Random musings of a macromolecular chemist in search of a vision (Professor Luca Pellegrini,  Department of Biochemistry, University of Cambrige)

2019-09-27 15:00: Biochemistry Friday Seminars - Phenotypes, faith, flotation and phages: bacterial gang culture and the triumph of death (Salmond Group)

2019-10-04 15:00: Biochemistry Friday Seminars -  "Deciphering induced pluripotency"  (Dr Jose Silva,  Department of Biochemistry, University of Cambrige)

2019-10-11 15:00: Biochemistry Friday Seminars - No Seminar (Speaker to be confirmed)

2019-10-18 15:00: Biochemistry Friday Seminars (Dr Katherine Stott, Department of Biochemistry, University of Cambrige)

2019-10-25 15:00: Biochemistry Friday Seminars - Alternative splicing: making biological order and complexity from nonsense, noise and disorder. (Professor Chris Smith, Department of Biochemistry, University of Cambrige)

2019-11-01 15:00: Biochemistry Friday Seminars - No Seminar (Speaker to be confirmed)

2019-11-08 15:00: Biochemistry Friday Seminars - Matthew Ratcliff - "Prodomain Relevance in GDNF Family Signalling"  Teodors Panteļejevs - "Structural and Chemical Biology of Rad51-BRC repeat interaction"  (Matthew Ratcliff and Theo Pantelejevs, Department of Biochemistry, University of Cambrige)

2019-11-15 15:00: Biochemistry Friday Seminars (Welch Group,  Department of Biochemistry, University of Cambrige)

2019-11-22 15:00: Biochemistry Friday Seminars - The Ral small GTPases: Inhibition and Interactions (Dr Helen Mott, Department of Biochemistry, University of Cambridge)

2019-11-29 15:00: Biochemistry Friday Seminars (Zegerman Group,  Department of Biochemistry, University of Cambrige)

2019-12-06 15:00: Biochemistry Friday Seminars (Dr Nianshu Zhang,  Department of Biochemistry, University of Cambrige)

2019-12-13 15:00: Biochemistry Friday Seminars- The signalling network of the Cdc42 effector protein, ACK (Owen Group)

2020-01-10 15:00: Biochemistry Friday Seminar - No Seminar (Speaker to be confirmed)

2020-01-17 15:00: Biochemistry Friday Seminar - (down)Regulation of Cancer Cell Growth (Prof J Taipale/O Kauko)

2020-01-24 15:00: Biochemistry Friday Seminar - New Solutions to Old Problems (Waller Group)

2020-01-31 15:00: Biochemistry Friday Seminar - A reorganisation of 3D genome folding during early differentiation (Laue Group)

2020-02-07 15:00: Biochemistry Friday Seminar - "Polyketide synthases: dissection and precision surgery" (Dr Bill Broadhurst)

2020-02-14 15:00: Biochemistry Friday Seminar - Putting the spotlight on the molecular choreography of viral RNAs (Dr Alex Borodavka)

2020-02-21 15:00: Biochemistry Friday Seminar - Molecular Imaging of Tumour Cell Death using Positron Emission Tomography’ (Speaker to be confirmed)

2020-02-28 15:00: Biochemistry Friday Seminar - The Resolution Revolution in Cryo-EM: Impact on Understanding DNA Double-Strand-Break Repair through Non-Homologous End Joining (NHEJ) (Blundell Group)

2020-03-06 15:00: Biochemistry Friday Seminar - “How the brain eats itself. Microglia in Dementia” (Prof Guy Brown)

2020-03-13 15:00: CANCELLED Biochemistry Friday Seminar - “Killing the oncogenic Wnt pathway” (Dr Marc de la Roche)

2020-03-20 15:00: Biochemistry Friday Seminar (Carrington Group)

2020-03-27 15:00: Biochemistry Friday Seminar (Dupree Group)

2020-04-24 15:00: Biochemistry Friday Seminar - Adventures in Wnt Signalling (Dr Marc de la Roche)