The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site


2007-04-17 12:00: Title to be confirmed (Michael Wakelam, Babraham Institute)

2007-04-24 12:00: RNAi Functional Analysis of Drug Resistance Pathways (Charlie Swanton, Cancer Research UK London Research Institute)

2007-05-01 12:00: Dimethyl sulfoxide to vorinostat-targeted histone deacetylase inhibitor – mechanisms of action as an anti-cancer drug (Paul Marks, Sloan-Kettering Institute, New York)

2007-05-08 12:00: Germline genetic predictors of prognosis in breast cancer (Paul Pharoah, Department of Oncology, Strangeways Research Laboratories)

2007-05-15 12:00: Experimental cancer medicine at the Dana Farber Cancer Institute (Lee Nadler, Dana Farber Cancer Institute, Boston, USA)

2007-05-29 12:00: Molecular heterogeneity of breast cancer - biological and clinical implications (Carlos Caldas, CRUK Cambridge Research Institute)

2007-06-05 12:00: Novel mechanisms of clinical drug resistance in ovarian cancer (James Brenton, CRUK Cambridge Research Institute)

2007-06-12 12:00: Towards a fuller understanding of inherited susceptibility to colorectal cancer (Richard Houlston, Institute of Cancer Research, Sutton)

2007-06-19 12:00: Exploiting senescence and anoikis in function-based oncogenomic screens (Daniel Peeper, Netherlands Cancer Institute)

2007-06-26 12:00: Developments in radiotherapy: new treatments for today and tomorrow (Neil Burnet, Deptartment of Oncology)

2007-07-17 12:00: Targeting RET kinase activity as a novel therapeutic strategy for medullary thyroid carcinoma (Francesca Carlomagno, University of Naples)

2007-09-04 12:00: "Targeting the Met receptor for cancer therapy" (Ermanno Gherardi) and "Preclinical efforts in Pancreatic Cancer" (Dave Tuveson) (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Dave Tuveson (CRUK Cambridge Research Institute))

2007-09-11 12:00: Molecular genetics of MALT lymphoma: application in diagnosis and prognosis (Prof Ming Du), tbc (Prof Robert Marcus) (Robert Marcus (Addenbrooke's Hospital) and Ming Du (University of Cambridge Department of Pathology))

2007-09-18 12:00: Title to be confirmed (David Baulcombe, Sainsbury Lab, Norwich)

2007-10-09 12:00: Proteins that license DNA replication (Laskey) Clinical exploitation of proteins that license DNA replication (Coleman) (Ron Laskey and Nick Coleman (Hutchison-MRC Research Centre))

2007-10-23 12:00: Gain-of-function JAK2 mutations in the human myeloproliferative disorders (Linda Scott (Cambridge Institute for Medical Research))

2007-11-13 12:00: "High throughput mapping of cis-regulatory DNA elements: From genomic arrays to functional biology" (George Follows) & "Rapid evolutionary turnover of transcription factor binding" (Duncan Odom) (George Follows (Cambridge Institute for Medical Research) and Duncan Odom (CRUK Cambridge Research Institute))

2007-11-20 12:00: Title to be confirmed (Margaret Stanley, Department of Pathology)

2007-11-27 12:00: Progress in prostate cancer and the androgen receptor (David Neal and Ian Mills, CRUK Cambridge Research Institute)

2007-12-04 12:00: Searching for and confirming common breast cancer risk alleles (Dunning) Update on Diet and Breast Cancer (Bingham) (Alison Dunning & Sheila Bingham, Department of Oncology & MRC Dunn Human Nutrition Unit)

2008-01-14 16:30: Integration of ubiquitin and phosphoinositide signals by the ESCRT machinery (Roger Williams, MRC-LMB, Cambridge)

2008-02-11 16:30: Role of membrane trafficking in mammalian germline sex determination (Ian Adams, MRC Human Genetics Unit, Edinburgh)

2008-03-10 16:30: Peroxisome maintenance in yeast (Ewald Hettema, Dept of Molecular Biology & Biotechnology, University of Sheffield)

2008-04-14 16:30: Early endosome trafficking in the model fungus Ustilago maydis (Gero Steinberg, School of Biosciences, University of Exeter)

2008-07-07 12:00: Insights into pathways regulating Rab GTPase activation (Dr Ruth Collins, Dept of Molecular Medicine, Cornell University)

2008-08-04 16:30: Imaging lysosome dynamics (Professor Dr Judith Klumperman, Cell Microscopy Center, Dept of Cell Biology, University Medical Center Utrecht)

2008-09-02 12:00: Chromatin modifying enzymes: their function and role in cancer (Tony Kouzarides, WT/CRUK Gurdon Institute)

2008-09-29 16:30: Role of the ESCRT machinery in HIV-1 budding and in late stages of cell division (Juan Martin-Serrano, Department of Infectious Diseases, King's College London School of Medicine)

2008-11-10 16:30: Insulin secretion: new (genetic) twists (Professor Guy Rutter)

2009-01-12 16:30: HIV assembly - is there really something special about macrophages? (Professor Mark Marsh)

2009-02-09 16:30: Cargo recognition in clathrin coated vesicles (David Owen, CIMR, Department of Clinical Biochemistry, University of Cambridge)

2009-04-20 16:30: SNAREs at the junction of signalling, transport and nutrition (Professor Mike Blatt, Dept of Plant Science, University of Glasgow)

2009-10-19 16:30: A new role for actin in vesicle traffic (Professor Robert Insall, CRUK Beatson Institute for Cancer Research, Glasgow)

2009-12-07 16:30: TIP47: A Rab9 key effector and sorting device for mannose-6-phosphate receptors, or an intracellular apolipoprotein ? (Professor Stefan Honing, Institute of Biochemistry I, University of Cologne)

2010-01-11 16:30: Peptide-dependent Trafficking of MHC Class I and the members of its Peptide Loading Complex (Sebastian Springer, Jacobs University Bremen, Germany)

2010-01-21 16:30: Mechanisms of endosome traffic in neurons (Victor Faundez, Department of Cell Biology, Emory University, USA)

2010-02-08 16:30: Rival forces of phosphorylation in nucleocytoplasmic transport and heterodimerization of hypoxia-inducible transcription factor HIF-1α (George Simos, Laboratory of Biochemistry, Faculty of Medicine, University of Thessaly, Greece)

2010-03-08 16:30: Molecular function of presynaptic protein scaffolds (Konark Mukherjee, Brandeis University, USA)

2010-05-10 16:30: Mechanisms of ER to Golgi transport: luminal calcium, vesicle coats, SNAREs, and neurodegeneration (Dr Jesse Hay, Division of Biological Sciences, University of Montana)

2011-01-10 16:00: New Insights into the regulation and function of Polo and Aurora kinases in mitosis and cytokinesis (Professor Francis Barr, University of Liverpool)

2011-02-07 16:00: Cell polarity and primary ciliogenesis in cell-cycle arrested cells (Dr Michel Bornens, Institut Curie, Paris)

2011-03-07 16:00: Parallels between wound healing and cancer - studies in flies, fish and mice (Professor Paul Martin, University of Bristol)

2011-03-24 16:00: Oocytes + Actin: Old Love - New Affairs (Dr Melina Schuh, MRC, Laboratory of Molecular Biology, Cambridge)

2011-04-18 16:00: Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope (Dr Iakowos Karakesisoglou, Senior Lecturer, University of Durham)

2011-04-27 13:00: The BBSome: a complex at the intersection of signaling trafficking and tubulin acetylation (Professor Maxence Nachury, Stanford University)

2011-05-16 16:00: Control of patterning and growth by the wingless morphogen (Dr Jean-Paul Vincent, MRC, NIMR, London)

2011-05-25 13:00: Its all in the neck: how the ESCRTs make multivesicular bodies (Dr Jim Hurley, Laboratory of Molecular Biology, USA)

2011-06-20 13:00: Investigating the Molecular Mechanism of Endocytosis (Professor Kathryn Ayscough, University of Sheffield)