All CRI seminars 2007-04-03 13:00: Title to be confirmed (Speaker to be confirmed) 2007-04-17 12:00: Title to be confirmed (Michael Wakelam, Babraham Institute) 2007-04-19 13:00: Breast Cancer (Daniel Birnbaum, Départment d'Oncologie Moléculaire, Institut de Cancérologie de Marseille) 2007-04-24 12:00: RNAi Functional Analysis of Drug Resistance Pathways (Charlie Swanton, Cancer Research UK London Research Institute) 2007-05-01 12:00: Dimethyl sulfoxide to vorinostat-targeted histone deacetylase inhibitor – mechanisms of action as an anti-cancer drug (Paul Marks, Sloan-Kettering Institute, New York) 2007-05-08 12:00: Germline genetic predictors of prognosis in breast cancer (Paul Pharoah, Department of Oncology, Strangeways Research Laboratories) 2007-05-15 12:00: Experimental cancer medicine at the Dana Farber Cancer Institute (Lee Nadler, Dana Farber Cancer Institute, Boston, USA) 2007-05-17 13:00: Lymphocyte Development (Amanda Fisher, MRC Clinical Sciences Centre, London) 2007-05-29 12:00: Molecular heterogeneity of breast cancer - biological and clinical implications (Carlos Caldas, CRUK Cambridge Research Institute) 2007-05-31 13:00: Group leader chalk talk (David Tuveson) 2007-06-05 12:00: Novel mechanisms of clinical drug resistance in ovarian cancer (James Brenton, CRUK Cambridge Research Institute) 2007-06-07 13:00: Title to be confirmed (Simon Tavaré, CRI) 2007-06-12 12:00: Towards a fuller understanding of inherited susceptibility to colorectal cancer (Richard Houlston, Institute of Cancer Research, Sutton) 2007-06-13 09:30: A tool of developmental biology for understanding tumorigenesis (Shin-ichi Ohnuma, Hutchison/MRC Research Centre, Dept of Oncology.) 2007-06-19 12:00: Exploiting senescence and anoikis in function-based oncogenomic screens (Daniel Peeper, Netherlands Cancer Institute) 2007-06-21 13:00: Human Sarcomas - Prostate and Bladder Cancers (Colin Cooper, Male Urological Cancer Research Centre Institute of Cancer Research) 2007-06-26 12:00: Developments in radiotherapy: new treatments for today and tomorrow (Neil Burnet, Deptartment of Oncology) 2007-06-27 09:30: Chromatin modifying enzymes and their involvement in cancer (Luke Hughes-Davies, Department of Oncology) 2007-07-04 09:30: Introduction to chemotherapy: role of Kaplan Meier curves in clinical cancer research (Luke Hughes-Davies, Department of Oncology) 2007-07-17 12:00: Targeting RET kinase activity as a novel therapeutic strategy for medullary thyroid carcinoma (Francesca Carlomagno, University of Naples) 2007-07-19 13:00: Role of NCOA4 protein in controlling DNA replication (Francesca Carlomagno, Università di Napoli Federico II, Naples, Italy) 2007-07-26 13:00: Oncogenes and Tumor Suppressors: The Good, The Bad and The Ugly (Gerard Evan, University of California, San Fransisco Comprehensive Cancer Center) 2007-09-04 12:00: "Targeting the Met receptor for cancer therapy" (Ermanno Gherardi) and "Preclinical efforts in Pancreatic Cancer" (Dave Tuveson) (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Dave Tuveson (CRUK Cambridge Research Institute)) 2007-09-11 12:00: Molecular genetics of MALT lymphoma: application in diagnosis and prognosis (Prof Ming Du), tbc (Prof Robert Marcus) (Robert Marcus (Addenbrooke's Hospital) and Ming Du (University of Cambridge Department of Pathology)) 2007-09-13 13:00: Centrosome cycle, cell division and chromosome segregation (Erich Nigg, Max Planck Institute of Biochemistry) 2007-09-17 14:00: Models to study breast cancer, invasion and the instability of the differentiated state (Mina Bissell, Lawrence Berkeley Laboratory, California) 2007-09-18 12:00: Title to be confirmed (David Baulcombe, Sainsbury Lab, Norwich) 2007-10-04 13:00: Viruses as gene therapy vectors (Inder Verma, Laboratory of Genetics, Salk Institute) 2007-10-09 12:00: Proteins that license DNA replication (Laskey) Clinical exploitation of proteins that license DNA replication (Coleman) (Ron Laskey and Nick Coleman (Hutchison-MRC Research Centre)) 2007-10-23 12:00: Gain-of-function JAK2 mutations in the human myeloproliferative disorders (Linda Scott (Cambridge Institute for Medical Research)) 2007-11-13 12:00: "High throughput mapping of cis-regulatory DNA elements: From genomic arrays to functional biology" (George Follows) & "Rapid evolutionary turnover of transcription factor binding" (Duncan Odom) (George Follows (Cambridge Institute for Medical Research) and Duncan Odom (CRUK Cambridge Research Institute)) 2007-11-15 13:00: Sequencing Mammalian Epigenomes (Tarjei Mikkelsen, Broad Institute, Massachusetts Institute of Technology) 2007-11-19 15:00: The Role of Epithelial Stem Cells in Inherited and Acquired Diseases (Dennis Roop, Charles C. Gates Chair in stem cell biology, School of Medicine, University of Colorado) 2007-11-20 12:00: Title to be confirmed (Margaret Stanley, Department of Pathology) 2007-11-27 12:00: Progress in prostate cancer and the androgen receptor (David Neal and Ian Mills, CRUK Cambridge Research Institute) 2007-12-04 12:00: Searching for and confirming common breast cancer risk alleles (Dunning) Update on Diet and Breast Cancer (Bingham) (Alison Dunning & Sheila Bingham, Department of Oncology & MRC Dunn Human Nutrition Unit) 2007-12-18 12:00: Beyond VEGF: vascular signaling targets for therapeutic manipulation (David Quinn, University of Southern California) 2008-01-22 12:00: Acute Myeloid Leukaemia: Molecular Pathogenesis, Prognostication and Targeted therapy (Brian Huntly) (Brian Huntly (Department of Haematology, Cambridge Institute of Medical Research) & Charles Crawley (Oncology Department, Addenbrookes Hospital)) 2008-01-24 13:00: Mouse Model for Cancer Biology (Scott Lowe, Cold Spring Harbor Laboratory) 2008-01-29 12:00: "Computational biology and cancer: the CRI perspective" and "Lung Cancer: A New Strategy" (Simon Tavaré, CRUK Cambridge Research Institute and Tim Eisen, Medical Oncologist (Lung and Renal cancer), Addenbrooke's Hospital) 2008-01-31 09:30: Ubiquitin / proteasome mediated protein degradation (Laura Itzhaki, MRC Cancer Cell Unit, MRC-Hutchison Research Centre) 2008-02-04 13:00: G-quadruplex Nucleic Acids: Non-coding Elements with Function? (Shankar Balasubramanian, University of Cambridge) 2008-02-12 12:00: Imaging biology in the cancer patient (K. Brindle) (Kevin Brindle (CRUK Cambridge Research Institute and Department of Biochemistry) and Athar Ahmad (Medical Oncologist, Colorectal Tumours), Addenbrooke's Hospital) 2008-02-19 12:00: Title to be confirmed (Stefanie Reichelt (CR UK Cambridge Research Institute) and Sara Booth (Palliative Care), Addenbrooke's Hospital) 2008-02-21 13:00: New Pathways of Tumour Agiogenesis and Hypoxia Response (Adrian Harris, Weatherall Institute of Molecular Medicine, Oxford) 2008-02-26 12:00: Experimental manipulation of the epidermis to study normal and cancer stem cells and The GIST of GISTS (Gastrointestinal Stromal tumours) (Fiona Watt, CRUK Cambridge Research Institute and Ramesh Bulusu, Clinical Oncologist (Lung/Upper GI/Lymphoma), Addenbrooke's Hospital) 2008-03-04 10:30: Biomarker Studies in Barrett's Esophagus and Esophageal Adenocarcinoma (Stephen Meltzer, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center) 2008-03-11 12:00: Title to be confirmed (Paul Pharoah (Strangeways Research Laboratories) and Rajesh Jena (Addenbrooke's Hospital))) 2008-03-18 12:00: 'Monitoring anticancer drug uptake by magnetic imaging and spectroscopy' and 'Breast cancer heterogeneity- a clinical challenge' (John Griffiths (CRUK Cambridge Research Institute) and Carlos Caldas (CRUK Cambridge Research Institute)) 2008-03-25 12:00: Title to be confirmed (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Helena Earl (Medical Oncologist; Sarcoma, breast and ovarian cancer), Addenbrooke's Hospital)) 2008-03-27 13:00: Proteins and Pathways Involved in Tumorigenicity (Jackie Lees, Massachusetts Institute of Technology) 2008-04-08 12:00: Breast Cancer Heterogeneity and the Cancer Stem Cell Hypothesis (John Stingl, Cambridge Research Institute) 2008-04-15 12:00: Title to be confirmed (Hugo Ford, Addenbrooke's Hospital) 2008-04-22 12:00: Chromosome translocations and gene fusions in breast cancer and Improving outcomes in melanoma: a fresh look (Paul Edwards (Hutchison/MRC Research Centre) and Pippa Corrie (Addenbrooke's Hosptial, Clinical Oncologist, Lung and Upper GI Cancer)) 2008-04-24 13:00: Cancer Epigenetics (Peter Laird, University of Southern California) 2008-04-29 12:00: Targeting Hyperactive Ras and Uncovering Mechanisms of Therapeutic Resistance in Genetically Engineered Mice (Kevin Shannon, University of California San Francisco) 2008-05-13 12:00: TBC (Adele Murrell, CRUK Cancer Research Institute and TBC) 2008-05-20 12:00: TBC (Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research Centre and Kate Fife, Addenbrooke's Hospital) 2008-05-27 12:00: Trials and Tribulations in the Management of Head and Neck Cancer (Sarah Jefferies, Addenbrooke's Hospital) 2008-06-09 13:00: Taming Glioblastoma -Targeting Angiogenesis (CRI Special Seminar) (Dr Steve Brem, Moffitt Cancer Center) 2008-06-10 12:00: 'Mechanisms of tamoxifen action and resistance' and 'Cambridge Oncology - Past, Present & Future: A tour from the 18th to 21st Century' (Jason Carroll, CRI and David Gilligan, Addenbrooke's Hospital) 2008-06-17 12:00: Using Bayesian analysis in randomised phase II clinical trials to determine the worth of proceeding to phase III (Cindy Billingham, University of Birmingham) 2008-06-24 12:00: TBC (Gill Murphy, CRI and Charles Wilson, Addenbrooke's Hospital) 2008-07-29 13:00: New Insight into the Cause(s) of Prostate Cancer (Brian E. Henderson, Keck School of Medicine, University of Southern California) 2008-09-02 12:00: Chromatin modifying enzymes: their function and role in cancer (Tony Kouzarides, WT/CRUK Gurdon Institute) 2008-09-03 12:00: Special seminar: Analysing the dynamic glycome (Lara Mahal, University of Texas, Austin) 2008-09-08 13:00: Use of cell-context-specific molecular interaction maps to identify master regulators of malignant transformations (Andrea Califano, Herbert Irving Comprehensive Cancer Center, Columbia University) 2008-09-16 12:00: Early phase clinical trials in Cambridge (Duncan Jodrell, Cambridge Research Institute and Department of Oncology) 2008-09-23 12:00: Title to be confirmed (Nick Carroll, Department of Radiology) 2008-09-30 12:00: Title to be confirmed (Richard Benson, Addenbrooke's Hospital) 2008-10-14 12:00: High-throughput cancer cell line screening: a tool for discovery (Ultan McDermott, Massachusetts General Hospital Cancer Center and Harvard Medical School) 2008-10-22 14:00: Fascin Protrusions in ECM-Cytoskeletal Networking and Metastasis (Josephine Adams, Lerner Research Institute, Cleveland) 2008-10-28 12:00: The role of Fam38 in integrin activation and lung cancer (Tariq Sethi, Chair of Respiratory and Lung Cancer Biology, Centre for Inflammation Research, University of Edinburgh) 2008-11-06 09:30: Mechanisms of DNA replication (Nick Robinson, MRC Cancer Cell Unit, Hutchison/MRC Centre) 2008-11-11 12:00: The West Anglia CLRN, TCRNs and the Coordinated System for gaining NHS Permission – How is it all going to work? (Lena Pettersson, Lead RM and G Manager, West Anglia NIHR CLRN) 2008-11-13 13:00: The Editorial Process Demystified (Andrew Sugden, International Managing Editor, Science Magazine) 2008-11-18 12:00: Colorectal neoplasia: what we know and don't know about genes and environment (John Potter, Fred Hutchinson Cancer Research Centre) 2008-11-25 12:00: The role of developmental biology in cancer research (Anna Philpott and Shin-ichi Ohnuma, Department of Oncology, MRC-Hutchison Research Centre) 2008-12-02 12:00: Delineating the Fanconi Anaemia DNA repair defect (KJ Patel, MRC Laboratory of Molecular Biology) 2008-12-03 09:30: Tumour suppressors 1 and 2 (Ashok Venkitaraman & Dave Tuveson; Hutchison/MRC Research Centre & Cambridge Research Institute) 2008-12-09 12:00: Title to be confirmed (Rebecca Fitzgerald, Cancer Cell Unit, Hutchison/MRC Research Laboratory) 2008-12-11 13:00: Microsignalosomes: Spatially Resolved Receptor-Signalling (Facundo Batista, Cancer Research UK, London Research Institute) 2009-01-06 12:00: Patterns of stem and progenitor cell fate in adult tissues (Professor Ben Simons, Department of Physics, Cambridge University) 2009-01-20 12:00: The evidence for lifestyle after cancer to reduce relapse and survival (Robert Thomas, Addenbrooke's Hospital) 2009-01-22 13:00: Regulation of self-renewal in cancer stem cells (Pier Pelicci, Department of Experimental Oncology, European Institute of Oncology, Milan) 2009-01-27 12:00: Sarcomas and the insulin-like growth factor pathway (Robert Maki, Memorial Sloan-Kettering Research Center) 2009-02-03 12:00: Role of the c-Myc-target gene Misu (NSun2) in regulating epidermal stem cell fate and its implications for cancer (Michaela Frye, Wellcome Trust Centre for Stem Cell Research, University of Cambridge) 2009-02-10 12:00: Clinical potential of functional ion channel expression in cancer (Mustafa Djamgoz, Imperial College London) 2009-02-19 13:00: Skin Development: Making Tissues from Stem Cells (Elaine Fuchs, Howard Hughes Medical Institute, The Rockefeller University) 2009-02-24 12:00: The role of cyclin-kinase inhibitors in the development of cancer (Nisar Malek, Hannover Medical School, Germany) 2009-02-26 09:30: Genetic association studies to find common disease susceptibility alleles (Alison Dunning, Strangeways Research Laboratories) 2009-03-03 12:00: The spatial organisation of Ras signaling (Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Germany) 2009-03-10 12:00: Radiation-induced bowel damage: let's put right what is wrong (Jervoise Andreyev, Royal Marsden Hospital) 2009-03-12 09:30: Intestinal cancer models and stem cell biology (Doug Winton, CRUK Cambridge Research Institute) 2009-03-17 12:00: Outreach chemotherapy programme (Pippa Corrie, Addenbrooke's Hospital) 2009-03-19 13:00: The adenomatous polyposis protein as a cytoskeletal architect: implications for early tumourigenesis (Inke Näthke, University of Dundee) 2009-03-24 12:00: What comes after cancer stem cells? (Doug Winton, CRUK Cambridge Research Institute) 2009-03-31 12:00: Analysis of early events after DNA damage in living cells; the HP1 paradigm (Anand Jeyasekharan, Hutchison/MRC Research Centre) 2009-04-07 12:00: Connecting Lung Epithelial Stem Cells and Lung Cancer by Stress-Activated Protein Kinases (Juan Jose Ventura, Wellcome Trust Centre for Stem Cell Research, University of Cambridge) 2009-04-21 12:00: Preservation of fertility in patients with cancer (Raj Mathur (Addenbrooke's Hospital) and Tom Mathews (Medical Director, Bourn Hall)) 2009-04-23 09:30: Stem cells and cancer (epithelial cancers) (Fiona Watt, CRUK Cambridge Research Institute) 2009-04-28 12:00: OPCML in Tumour Gene Therapy in Ovarian Cancer (Hani Gabra, Faculty of Medicine, Imperial College London) 2009-05-05 12:00: Taming the tiger by the tail: modulation of DNA damage responses by telomeres (David Lydall, Institute for Ageing and Health, Newcastle University) 2009-05-07 09:30: Assessing responses to cancer therapy using molecular imaging magnetic resonance methods (Kevin Brindle and John Griffiths, CRUK Cambridge Research Institute) 2009-05-14 09:30: Inherited susceptibility to cancer (Bruce Ponder, CRUK Cambridge Research Institute) 2009-05-19 12:00: Common germline variation and colorectal cancer (Richard Hubner, Royal Marsden Hospital) 2009-05-21 13:00: The Role of Risk Stratification in Treatment Selection for Patients with Prostate Cancer (Carlos Cordon-Cardo, Herbert Irving Comprehensive Cancer Center, Columbia University) 2009-05-26 12:00: Using genetics to personalize melanoma therapy (Keiran Smalley, Moffitt Cancer Center) 2009-06-02 12:00: A model for all genomes: the role of RNA polymerases fixed in factories (Peter Cook, University of Oxford) 2009-06-09 12:00: Translational imaging studies in ovarian cancer (James Brenton, CRUK Cambridge Research Institute and Evis Sala, Department of Radiology) 2009-06-11 13:00: Breast cancer: origins and evolution (Kornelia Polyak, Dana-Farber Cancer Institute, Harvard Medical School) 2009-06-16 12:00: Is brain cancer a stem cell disease? (Colin Watts, Department of Clinical Neurosciences) 2009-06-23 12:00: Germ Cell Tumours (GCTs) of Young People: Clinical and Biological Approaches (James Nicholson and Matthew Murray, Paediatrics, Addenbrooke's Hospital) 2009-06-30 12:00: Genome scans in breast and prostate cancer - what have we learned & where next? (Doug Easton, Strangeways Research Laboratory) 2009-07-02 09:30: Prospective translational research in clinical trials (Helena Earl, Department of Oncology) 2009-09-08 12:00: Adoptive T Cell Therapy of Cancer (Cassian Yee, Fred Hutchinson Research Center, Seattle) 2009-09-15 12:00: Clinical Aspects of Proton Radiotherapy (Prof Tony Lomax, Head of Medical Physics, Centre for Proton Radiation Therapy, Paul Scherrer Institute, Switzerland) 2009-09-29 12:00: Molecular Mechanisms of Cellular Senescence in Cancer and Ageing (Fabrizio d'Adda di Fagagna, IFORM-IEO, Milan) 2009-10-13 12:00: "Immunostimulatory antibodies in cancer treatment" (Prof. Peter Johnson, Professor of Medical Oncology, University of Southampton) 2009-10-20 12:00: "Phospholipase and lysophospholipase D signalling in cancer" (Prof. Michael Wakelam, Institute Director, The Babraham Institute) 2009-10-22 13:00: Adult stem cells: from concepts to reality (Connie Eaves, Terry Fox Laboratory, BC Cancer Research Centre, Vancouver) 2009-10-27 12:00: Steroid Hormone Receptors in Prostate Cancer: A Hard Habit to Break? (Dr Gerhardt Attard, The Institute of Cancer Research and the Royal Marsden Hospital) 2009-11-03 12:00: The irreversibility of cell cycle transitions: why the clock never turns back (Frank Uhlmann, CRUK London Research Institute) 2009-11-17 12:00: "The Arguments for and against Sentinel Node Biopsy (SNB) in Melanoma" (Prof. J Meirion Thomas, Royal Marsden Hospital & Imperial College, London) 2009-11-24 12:00: “Intensity modulated radiotherapy for children’s tumours and estimation of the carcinogenic risk” (Dr Michael Williams & Dr Gail Horan, Addenbrooke's Hospital) 2009-11-26 09:30: Cell Signalling (Ermanno Gherardi, MRC Laboratory of Molecular Biology) 2009-11-26 13:00: Lung cancer chemoprevention: the role of eicosanoids (Mark Geraci, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver) 2009-12-01 12:00: Cellular senescence: molecular mechanisms and implications for cancer and aging (Peter Adams, Beatson Institute for Cancer Research, Glasgow) 2009-12-15 12:00: The new LAW of microRNA-mediated gene silencing: implications for lung cancer development (Dr Tyson V. Sharp, School of Biomedical Sciences, University of Nottingham) 2010-01-06 13:00: A tumoral stromal cell that mediates immune suppression (Douglas T. Fearon, Wellcome Trust Immunology Unit, Cambridge) 2010-01-12 12:00: PREDICT: A NEW UK PROGNOSTIC MODE THAT PREDICTS SURVIVAL FOLLOWING SURGERY FOR INVASIVE BREAST CANCER (GC Wishart, EM Azzato, PDP Pharoah, DC Greenberg, J Rashbass, O Kearins, G Lawrence, C Caldas C, PM Ravdin) (Prof. Gordon Wishart, Addenbrooke's Hospital) 2010-01-19 12:00: Investigating the interaction of Radiotherapy & Temozolomidefor Glioblastoma (Dr Raj Jena, Addenbrooke's Hospital) 2010-01-21 13:00: Physical limits of cell migration (Katarina Wolf, Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences) 2010-01-26 12:00: HPV vaccines - will they do their job? (Prof. Margaret Stanley, Dept. of Pathology, University of Cambridge) 2010-02-02 12:00: Can we age in utero? Can we kill cancer cells by making them replicate faster? And other ATR stories… (Oscar Fernandez-Capetillo, Spanish National Cancer Research Centre (CNIO)) 2010-02-09 12:00: High-throughput Cancer Cell line Screens: Linking Drug Response to Molecular Signatures (Dr Ultan McDermott, Cancer Genome Project, Wellcome Trust Sanger Institute) 2010-02-11 09:30: Why computational biology is useful in the cancer world (Simon Tavaré, CRUK Cambridge Research Institute) 2010-02-16 12:00: The prognostic significance of subtypes of breast cancer classified using immunohistochemistry (Dr Paul Pharoah, Strangeways Research Laboratory/Oncology) 2010-02-18 13:00: JNK signalling in stem cells and cancer (Axel Behrens, London Research Institute, Lincoln's Inn Fields Laboratories) 2010-02-23 12:00: CANCELLED (Dr Alison Dunning, Strangeways Research Laboratory & Dept. of Oncology) 2010-03-02 12:00: The Role of the Receptor Tyrosine Kinase Antagonist, Lrig1, in Normal Tissue Homeostasis and Cancer (Kim Jensen, Anne McLaren Laboratory for Regenerative Medicine and Department of Oncology) 2010-03-09 12:00: "The Fine Scale Mapping of Breast Cancer Loci found via GWAS - searching for the Causative Variants" (Dr Alison Dunning, Strangeways Research Laboratory) 2010-03-16 12:00: Deciphering the Mammary Epithelial Cell Hierarchy (Dr John Stingl, CRUK Cambridge Research Institute) 2010-03-30 12:00: "Non-Invasive Diagnosis of Brain Cancer" (Prof. John Griffiths, CRUK Cambridge Research Institute) 2010-04-13 12:00: CANCELLED (Dr James Brenton, CRUK Cambridge Research Institute) 2010-04-20 12:00: The NCAG Report: Delivering a World Class Chemotherapy Service (Prof Roger James, Previously: • Deputy Medical Director Maidstone and Tunbridge Wells NHS Trust • Medical Director Kent & Medway Cancer Network) 2010-04-22 09:30: Stem cell fate (Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research centre) 2010-04-22 13:00: In vivo quantitative proteomics to study skin cancer progression (Sara Zanivan, Department of Proteomics and Signal Transduction, Max-Planck Institute for Biochemistry) 2010-04-27 12:00: “Macromolecular interactions in the control of chromosome instability” (Prof. Ashok Venkitaramann, (Hutchison-MRC Research Centre)) 2010-04-29 09:30: Radiotherapy in the management of cancer (Neil Burnet, Department of Oncology and Addenbrooke's Hospital) 2010-05-04 12:00: Mechanisms regulating neural differentiation (Kate Storey, University of Dundee) 2010-05-11 12:00: "Cellular Senescence as a Tumour Suppressor Mechanism, Particular Focus will be on the Autophagy/mTOR Pathway" (Dr Masashi Narita, CRUK Cambridge Research Institute) 2010-05-18 12:00: "Stem cell identity and mRNA export: unexpected roles of geminin and GANP" (Prof. Ron Laskey, Hutchison/MRC Research Centre) 2010-05-20 09:30: Talk Cancelled (Guillermo de la Cueva Mendez, Hutchison/MRC Research Centre Cancer Cell Unit.) 2010-05-25 12:00: "A New Window of Opportunity in Prostate Cancer" (Dr Danish Mazhar, Addenbrooke's Hospital) 2010-05-27 13:00: Mapping Synthetic Genetic Interaction Networks by High-throughput RNAi (Michael Boutros, Division of Signaling and Functional Genomics, German Cancer Research Center) 2010-06-10 09:30: New approaches to the clinical management of cervical cancer (Nick Coleman, MRC Cancer Cell Unit, Hutchison-MRC Research Centre) 2010-06-15 12:00: Dynamic Notch signaling in neural progenitor cells (Ryoichiro Kageyama, Kyoto University, Japan) 2010-06-17 13:00: View of the Cancer Epigenome from Biological and Translational Perspectives (Stephen B. Baylin, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore) 2010-06-22 12:00: "Gastro Intestinal Stroma Tumours (GISTS)" (Dr Ramesh Bulusu, Addenbrooke's Hospital) 2010-06-29 12:00: "Breast Radiotherapy - Past, Present and Future" (Dr Charlotte Coles, Addenbrooke's Hospital) 2010-09-07 12:00: Unravelling cancer cell signalling networks and screening for novel drug targets (Daniel Peeper, The Netherlands Cancer Institute) 2010-09-14 12:00: Interactions of Epidermal Growth Factor Receptor Inhibition with DNA damage in the treatment of gastrointestinal cancer (Prof Daniel Hochhauser, University College London) 2010-09-16 13:00: Transcriptional Lego: Predictable control of gene expression by manipulating promoter building blocks (Eran Segal, Weizmann Institute of Science) 2010-09-21 12:00: Pathway Analysis of Glioblastoma Tissue After Preoperative Treatment with the EGFR Tyrosine Kinase Inhibitor Gefitinib – A Phase “0 Trial” (Dr Monika Hegi, University Hospital (CHUV), Lausanne, Switzerland) 2010-09-28 12:00: “EGFR Mutation Screening in NSCLC” (Dr David Gonzalez de Castro, The Institute of Cancer Research and Royal Marsden Hospital) 2010-10-12 12:00: "Imaging Tumour Cell Death" (Prof. Kevin Brindle, CRUK Cambridge Research Institute) 2010-10-19 12:00: "Brain Metastases – a cross cutting theme: Review of the Brain Metastasis Service and Future Research Potential" (Dr Sarah Jefferies, Addenbrooke's Hospital) 2010-10-21 13:00: Biological lessons from presurgical studies of breast cancer (Mitch Dowsett, Institute of Cancer Research, Royal Marsden Hospital) 2010-10-26 12:00: "Chromosome Translocations and Tumour Suppressors in Breast Cancer" (Dr Paul Edwards, Hutchison/MRC Research Centre) 2010-11-11 13:00: Inflammation, metabolism, ageing and cancer: Dangerous Liaisons (Michael Karin, University of California, San Diego) 2010-11-18 09:30: Oncogenes and Tumour Suppressors 1 & 2 (Ashok Venkitaraman & Dave Tuveson; Hutchison/MRC Research Centre & Cambridge Research Institute) 2010-11-23 12:00: Targeting NG2 Cells in Glioblastoma (Dr Colin Watts, Cambridge Centre for Brain Repair) 2010-11-25 09:30: Tumour suppressors mechanisms and cellular senescence (Masashi Narita, CRUK Cambridge Research Institute) 2010-11-30 12:00: "Susceptibility to Cancer - What's New?" (Prof Doug Easton, Strangeways Research Laboratory) 2010-12-02 14:30: Neuroblastoma- Disordered Developmental Programs Contribute to Tumorigenesis (Prof Carol Thiele, National Cancer Institute, USA) 2010-12-14 12:00: RCC Cinderella comes of age (Prof. Tim Eisen, Dept. of Oncology, University of Cambridge & Addenbrooke's Hospital) 2010-12-21 12:00: “Breast MRI by the Shutter-Speed Method: Elimination of Unnecessary Breast Biopsies" (Dr Charles S. Springer, Jr., Advanced Imaging Research Centre. Oregon Health & Science University) 2011-01-20 09:30: Systems approaches to understanding transcriptional regulation (Duncan Odom, CRUK Cambridge Research Institute) 2011-01-20 13:00: Reverse Phenotyping: Towards an integrated (epi)genomic approach to complex phenotypes and common disease. (Stephan Beck, UCL Cancer Institute) 2011-01-25 12:00: "Leukaemia stem cells: how normal stem cell function is subverted in haematological malignancies" (Dr Brian Huntly, Department of Haematology) 2011-01-27 09:30: Control of DNA Replication (Ron Laskey, MRC Cancer Cell Unit, MRC-Hutchison Research Centre) 2011-02-01 12:00: Application of Systems Biology Approaches to Study Cell Signalling and Transcription (Prof Mike White, University of Liverpool) 2011-02-15 12:00: "Targetting pre-neoplasia in the bronchus" (Dr Robert Rintoul, Papworth Hospital) 2011-02-17 13:00: MAL: linking the actin cytoskeleton to transcriptional regulation (Richard Treisman, Cancer Research UK London Research Institute, Lincoln's Inn Fields) 2011-02-21 13:00: Analysis of Sprouty2 in human prostate carcinogenesis (Hing Leung, Beatson Institute for Cancer Research) 2011-02-22 12:00: Mesothelioma: a disease of our time (Dr David Gilligan, Addenbrooke's Hospital) 2011-03-08 12:00: "FGF-2, S6 Kinase 2 and Chemo-resistance in Lung Cancer" (Prof. Michael Seckl, Imperial College, London and Charing Cross Hospital) 2011-03-15 12:00: "The Cambridge breast cancer program- recent progress" (Dr Carlos Caldas, CRUK Cambridge Research Institute) 2011-04-12 12:00: "Somatic Genetics of Human Cancer - Moving Towards Large Scale Resequencing of Cancer Genomes" (Dr Andy Futreal, The Wellcome Trust Sanger Institute, Hinxton) 2011-04-14 09:30: Signal transduction and membrane trafficking (Ian Mills, CRUK Cambridge Research Institute) 2011-04-26 12:00: CANCELLED (Dr Vincent Gnanapragasam, Hutchison/MRC Research Centre & Addenbrooke's Hospital) 2011-05-03 12:00: CANCELLED (Prof Sibylle Mittnacht, The Institute of Cancer Research) 2011-05-10 12:00: "Multi-site post-translational modification as a quantitative regulator of transcriptional output during neurogenesis" (Dr Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre) 2011-05-17 12:00: CANCELLED (Prof. Roy Rampling, University of Glasgow and The Beatson Cancer Centre, Glasgow) 2011-05-24 12:00: “What lessons can we learn from transcriptional evolution in cancer research?” (Dr Duncan Odom, CRUK Cambridge Research Institute) 2011-05-26 09:30: Genomic Imprinting and Cancer (Adele Murrell, CRUK Cancer Research Institute) 2011-05-31 12:00: SOCCAR trial: an update (Dr Joe Maguire, Consultant Clinical Oncologist, Clatterbridge Centre for Oncology) 2011-06-07 12:00: "Developing Medicines for Pancreatic Cancer" (Dr Dave Tuveson, CRUK Cambridge Research Institute) 2011-06-14 12:00: "Advances in Head and Neck Radiotherapy" (Dr Chris Nutting, Royal Marsden Hospital) 2011-06-16 13:00: Changing Cancer Mortality (Richard Peto, Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford) 2011-06-21 12:00: ‘Viral and host contributions to cervical carcinogenesis’ (Dr Nick Coleman, Department of Pathology & Hutchison/MRC Research Centre) 2011-06-28 12:00: The ATM-mediated DNA damage response: moving between the forest and the trees (Dr Yossi Shiloh, Tel Aviv University, Israel) 2011-07-07 13:00: Integrated Solutions in Cancer Genomics (Edison Liu, Genome Institute of Singapore) 2011-07-14 13:00: Modeling non-familial colon cancer susceptibility in mice (David Threadgill, Department of Genetics, North Carolina State University) 2011-09-06 12:00: Haploid Genetic Screens in Human Cells (Dr Thijn Brummelkamp, Netherlands Cancer Institute) 2011-09-20 12:00: DNA repair inhibitors in cancer treatment (Prof Hilary Calvert, UCL Cancer Institute) 2011-10-04 12:00: Tumour-stroma Interactions in Breast Cancer (Prof Clare Isacke, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research) 2011-10-18 12:00: ‘Genetic predisposition to cancer’ (Prof Bruce Ponder, Cancer Research UK Cambridge Research Institute) 2011-10-20 13:00: Transcriptional Regulation of Cell State (Richard Young, Whitehead Institute for Biomedical Research and M.I.T.) 2011-11-01 12:00: Cancer Gene Discovery in the Mouse (Dr David Adams, Wellcome Trust Sanger Institute) 2011-11-10 09:30: Barrett's oesophagus as a model for early cancer detection/treatment (Rebecca Fitzgerald, Hutchison/MRC Research Centre) 2011-11-17 13:00: The intrinsic and extrinsic regulation of stem cells self-renewal (Sean J Morrison, Children’s Research Institute, University of Texas Southwestern Medical Center) 2011-12-01 09:30: Cancer Therapeutics (Duncan Jodrell, Cambridge Research Institute and Department of Oncology) 2011-12-06 12:00: Integration of Cell Growth and Cell Metabolism by Myc (Prof Martin Eilers, Theodor-Boveri-Institute, University of Würzburg, Germany) 2011-12-08 13:00: *CANCELLED* Wnt signalling, Lgr5 stem cells and cancer (Hans Clevers, Hubrecht Institute) 2011-12-13 12:00: Neo-adjuvant radiochemotherapy in breast cancer (Dr Alain Fourquet, Department of Radiation Oncology, Institut Curie, Paris) 2012-01-19 13:00: Inflammatory skin disease and Cancer: Functions of AP-1 (Fos/Jun) in mice and humans (Erwin Wagner, CNIO Madrid) 2012-01-24 12:00: “Imaging Biomarkers in Cancer” (Prof. Fiona Gilbert, Dept. of Radiology) 2012-02-02 09:30: MRI and MRS in cancer research and cancer treatment (John Griffiths, Cambridge Research Institute) 2012-02-07 12:00: Transcriptional control of EMT and malignant tumor progression (Prof Gerhard Christofori, University of Basel, Switzerland) 2012-02-14 12:00: "Radiotherapy toxicity, Radiogenomics and RAPPER" (Dr Gill Barnett, Dept. of Oncology) 2012-02-16 09:30: Imaging tumour responses to treatment (Kevin Brindle, Dept. Biochemistry and Cambridge Research Institute) 2012-02-16 13:00: Chromosome Segregation and Genome Stability (David Pellman, Dana-Farber Cancer Institute, Harvard Medical School) 2012-02-21 12:00: "Myeloproliferative neoplasms – JAK/STAT signalling and stem cell subversion" (Prof Tony Green, University of Cambridge Department of Haematology) 2012-02-23 09:30: Functional breast cancer genomics: from basic biology to clinical application (Carlos Caldas, CRI) 2012-02-28 12:00: "DICER1 and miRNA processing - a novel paradigm in cancer predisposition" (Dr Marc Tischkowitz, Dept of Medical Genetics, University of Cambridge) 2012-03-13 12:00: "Re Service Reforms in the new Commissioning Landscape" (Hannah Farrar, Director of Strategy and System Management, NHS, London) 2012-03-15 09:30: Clinical lectures on prostate, bladder, renal and testis cancer (David Neal, Cancer Research UK Cambridge Research Institute) 2012-03-15 13:00: Pluripotency, Etc. (Ihor Lemischka, Mount Sinai Medical Centre) 2012-03-20 12:00: "Thalidomide and its analogues ; How molecules selected for anti-TNFa activity affect so many different pathways with direct binding with Cereblon mediating both anti proliferative and Immunomodulatory functions" (Jerome B. Zeldis CEO of Celgene Global Health & Angus Dalgleish, St George's Hospital London) 2012-03-27 11:30: "Exploiting ASS1 deficiency in the treatment of mesothelioma" (Dr Peter Szlosarek, Cancer Research UK Clinician Scientist, Senior Lecturer and Honorary Consultant in Medical Oncology, Barts and The London) 2012-04-03 12:00: Always on guard: p53 dynamics in single living cells (Dr Alexander Loewer, Berlin Institute for Medical Systems Biology, Max Delbrueck Center, Germany) 2012-04-04 13:00: Towards unification of genetic and hierarchy models of tumor heterogeneity (John Dick, University of Toronto) 2012-04-24 12:00: CANCELLED (Prof Richard Sullivan, Professor, Kings College London, Director, Centre for Global OncoPolicy & Health Kings Health Partners) 2012-05-03 17:00: ALK Hunting in Colorado - new drugs for lung cancer's new diseases (Dr Ross Camidge, University of Colorado Hospital (UCH) and the University of Colorado Cancer Center,) 2012-05-08 12:00: Investigating key effectors downstream of APC (adenomatous polyposis coli) deletion in vivo (Prof Owen Sansom, Beatson Institute, Glasgow) 2012-05-15 12:00: "Strategies to enhance effectiveness of Radiotherapy in Pancreatic Cancer" (Dr Thomas Brunner, Gray Institute for Radiation Oncology and Biology, Oxford) 2012-05-17 13:00: Common and rare variants in the sequence of the human genome that affect the risk of cancers and other diseases of man (Kari Stefansson, deCODE Genetics, Iceland) 2012-05-29 12:00: Pancreatic cancer: Genetic models to develop novel diagnostic and therapeutic strategies (Dr Dieter Saur, The Technical University of Munich) 2012-06-12 12:00: Cancer-related inflammation (Dr Thorsten Hagemann, Barts Cancer Institute, Queen Mary University of London) 2012-06-21 13:00: Cellular Conversations that Control Cell Fate (Thea Tlsty, University of California, San Francisco) 2012-06-21 16:00: Understanding Response & Resistance Mechanisms to Targeted Therapy (Dr Keith Flaherty, Director of Developmental Therapeutics at Massachusetts General Hospital) 2012-07-19 13:00: The role of telomeres and telomerase in stem cell biology, cancer and ageing (Maria Blasco, CNIO, Madrid) 2012-08-14 12:00: 'Circulating Tumour Cells: Biomarker Utility and Insights to Metastasis' (Professor Caroline Dive, Clinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester) 2012-09-11 13:00: Lgr5 stem cells in self-renewal and cancer (Hans Clevers, Hubrecht Institute, The Netherlands) 2012-09-20 13:00: Challenges in Building a Genomic Prescribing System (Mark J. Ratain, Director, Center for Personalized Therapeutics, University of Chicago) 2012-10-03 13:00: The Ras pathway in cancer therapy (Frank McCormick, UCSF Helen Diller Family Comprehensive Cancer Center) 2012-11-06 12:00: Signalling Networks in Cell Proliferation and Fate Control (Professor Sibylle Mittnacht, UCL Cancer Institute) 2012-11-06 16:00: A genomic Odyssey of predicting drug response: is Ulysses home yet? (Dr Federico Innocenti, UNC Institute for Pharmacogenomics and Individualized Therapy) 2012-11-07 10:30: A systems view of the cancer cell: from missing genetic variability to combination therapy (Andrea Califano, Columbia University) 2012-11-13 12:00: "Towards personalized medicine in Breast Cancer" (Prof. Dr. Sabine C. Linn, medical oncologist Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands) 2012-11-15 13:00: PLEASE NOTE THAT THIS TALK HAS BEEN CANCELLED (Danny Reinberg) 2012-11-20 12:00: Mechanisms of Estrogen Receptor Transcription in Breast Cancer (Dr Jason Carroll, CRUK Cambridge Research Institute) 2012-11-27 12:00: Cellular responses to DNA damage: translating molecular insights towards new cancer therapies (Prof Steve Jackson, Head of Cancer Research UK Laboratories The Gurdon Institute, Cambridge) 2012-11-29 09:30: **Talk postponed** Introduction to statistics (Sarah Vowler, CRI) 2012-12-04 12:00: Localisation-based feedback controls during mitosis and the maintenance of chromosomal stability (Dr Adrian Saurin, University Medical Center Utrecht, The Netherlands) 2012-12-13 09:30: Microtubules: boring polymers or the Achilles heel of cancer? (Fanni Gergely, CRUK Cambridge Research Institute) 2013-01-17 09:30: Estrogen receptor and its role in transcription and breast cancer (Jason Carroll, CRI) 2013-01-24 09:30: Stem cells and cancer (John Stingl, Cambridge Research Institute) 2013-01-31 09:30: Proteinases and Cancer (Gill Murphy, CRUK Cambridge Research Institute) 2013-02-05 12:00: Telomeres and the challenges to chromosome integrity (Dr Julie Cooper, London Research Institute) 2013-02-19 12:00: Challenges in Implementing Personalized Cancer Medicine: the IGR experience (Professor Alexander Eggermont, Director General, Institut de Cancérologie Gustave Roussy, France) 2013-02-21 13:00: Molecular dissection and targeting of epigenetic machinery in AML stem cells (Eric So, Department of Haematological Medicine, King's College London) 2013-03-07 09:45: Epigenetic cancer conspirators: DNA methylation, non-coding RNA and chromatin loops (Adele Murrell, CRUK Cambridge Institute) 2013-03-12 12:00: CANCELLED (Dr Fiona Blackhall, Manchester University, Manchester Cancer Research Centre Lung Group Lead) 2013-03-21 09:30: Computational biology (Florian Markowetz, Cancer Research UK Cambridge Research Institute) 2013-03-28 13:00: Impact of cancer- and stroma-cell-derived lysosomal proteases on cancer invasion and metastasis (Thomas Reinheckel, University of Freiburg) 2013-04-18 13:00: The impact of cohesin on the regulation of gene expression and the organization of chromatin (Matthias Merkenschlager, Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College London) 2013-04-23 12:00: “The identification of patients who benefit from targeted therapy in renal cancer” (Professor Thomas Powles, Barts Cancer Institute, Queen Mary University of London) 2013-05-07 12:00: Macrophages Into Tumor Hypoxic Areas: Should I Stay Or Should I Go? (Dr Massimiliano Mazzone, VIB Vesalius Research Center, Belgium) 2013-05-14 12:00: ‘CLL – from chemotherapy to targeted kinase inhibition’ (Dr George Follows, Consultant Haematologist, Addenbrooke's ) 2013-05-28 12:00: "Renal Cancer and Oxygen Sensing" (Prof Patrick Maxwell, Regius Professor of Physic, University of Cambridge) 2013-06-04 12:00: Control of cytokinesis and the dark side of actomyosin forces (Dr Mark Petronczki, London Research Institute) 2013-06-11 12:00: Economics of Cancer Medicines (Professor Richard Sullivan, Guy's Hospital, London) 2013-06-20 13:00: Duplicating the Human genome: The Origin Recognition Complex et al (Bruce Stillman, FAA, FRS - Cold Spring Harbour Laboratory, New York) 2013-06-25 12:00: "Image guidance – benefits and risks" (Professor Marcel van Herk, Imaging Physicist, Project Leader, The Netherlands Cancer Institute) 2013-07-02 13:00: Genetic modifiers and microenvironmental control of tumor invasiveness (Prof Douglas Hanahan, EPFL, Switzerland ) 2013-07-16 12:00: Risk and uncertainty in radiotherapy. Why I am the weakest link? (Dr Tom Roques, Lead of Head and Neck Cancer Multidisciplinary Team, Norfolk and Norwich Hospital) 2013-07-18 13:00: HER2 and EGFR: Signalling mechanisms and next generation cancer therapies (Yosef Yarden, Weizmann Institute of Science, Israel) 2013-09-03 12:00: Insights for the role of tumour-related inflammation and stem cells in Drosophila (Dr Marcos Vidal, Beatson Institute, Glasgow ) 2013-09-10 12:00: Advances in non-surgical treatment for cervix cancer (Dr Li Tee Tan, Addenbrooke's ) 2013-09-19 13:00: Inflammation and Cancer: Reprogramming the immune microenvironment as an anti-cancer therapeutic strategy (Lisa M. Coussens. Department of Cell & Developmental Biology, Knight Cancer Institute, Oregon Health & Sciences University) 2013-09-24 12:00: CANCELLED (Professor Charles Swanton, CRUK & UCL Trials Centre, UCL) 2013-10-01 12:00: Target-Based Approach in Early-Phase Clinical Trials in Cancer (Filip Janku, Investigational Cancer Therapeutics, (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, Houston) 2013-10-08 12:00: Spotlight on Cambridge Clinical Trials; Presentations from the American Society of Oncology (ASCO) Annual Meeting 2013 (Prof Tim Eisen, Dr Hugo Ford, Dr Pippa Corrie & Dr Kate Fife) 2013-10-15 13:00: Chromatin and its Impact on Gene Expression and Cellular Memory (Danny Reinberg, Howard Hughes Medical Institute, NYU School of Medicine) 2013-10-17 09:30: Development (Anna Philpott, Department of Oncology) 2013-10-29 12:00: CANCELLED - Scottish Collaboration On Translational Research into Renal Cell Cancer, developing a systems medicine approach to personalised treatment (Mr Grant Stewart, Department of Urology and Edinburgh Urological Cancer Group,Western General Hospital. Edinburgh) 2013-11-04 16:00: The p53 pathway: 21 years of the "guardian of the genome" (Prof Sir David Lane, Chief Scientist, A*STAR, Singapore) 2013-11-14 09:30: Introduction to cancer in Cambridge (BP) followed by Cell cycle and checkpoints (AP) (Bruce Ponder and Anna Philpott, Department of Oncology) 2013-11-21 09:30: Stem cells and cancer (Phil Jones, MRC Cancer Unit) 2013-11-26 12:00: "The Cambridge Breast Cancer Programme" (Prof Carlos Caldas, CRUK Cambridge Research Institute) 2013-11-28 13:00: Hallmarks of Cancer: Applications to Cancer Medicine? (Douglas Hanahan, Swiss Institute for Experimental Cancer Research) 2013-12-03 12:00: The autophagy signaling network in the coordination of a cell's response (Prof Francesco Cecconi, University of Tor Vergata, Italy ) 2013-12-05 09:30: Tumour metabolism (Christian Frezza, MRC Cancer Unit) 2013-12-12 09:30: Metastasis (Gill Murphy, Cancer Research UK Cambridge Institute) 2013-12-12 13:00: Harnessing Genetic Dependencies in Cancer Therapy (Alan Ashworth, The Institute of Cancer Research, London) 2013-12-17 12:00: CANCELLED (Prof Josep Tabernero, Head, Medical Oncology Department, Vall d' Hebron University Hospital, Barcelona, Spain) 2014-01-07 12:00: Chasing metabolic alterations in cancer (Dr Arkaitz Carracedo, CIC bioGUNE, (Center for Cooperative Research in Biosciences), Derio, Spain) 2014-01-14 12:00: Personalized medicine initiative at Gustave Roussy ( Professor Jean-Charles SORIA - Chef de Service, Professor of Medicine and Medical Oncology, Paris University XI and cancer specialist at Institut Gustave, Roussy.) 2014-01-16 13:00: NextGen Research: Enabling distributed teams of experts and the engaged public to solve complex biomedical problems (Stephen Friend, Sage Bionetworks, Seattle) 2014-02-04 12:00: Translating Tumour Metabolism into New Diagnostics and Novel Anti-Cancer Therapeutics (Professor Michael Lisanti, Director of the Breakthrough Breast Cancer Research Unit, University of Manchester) 2014-02-06 09:30: Circulating DNA and diagnostics (Nitzan Rosenfeld, Cancer Research UK Cambridge Institute) 2014-02-11 12:00: “What can we do to accelerate the discovery of new medicines for patients?” (Professor Chas Bountra, Head of Structural Genomics Consortium, University of Oxford, Nuffield Dept of Clinical Medicine ) 2014-02-12 09:30: Transcriptional regulation and techniques (Duncan Odom, Cancer Research UK Cambridge Institute) 2014-02-27 09:30: Computational biology (Florian Markowetz, Cancer Research UK Cambridge Institute) 2014-03-04 12:00: Cell death and autophagy in response to inhibition of glycolysis (Dr Cristina Muñoz Pinedo, IDIBELL, Barcelona, Spain) 2014-03-06 09:30: Solid vs. non-solid tumours (Brian Huntly, Department of Haematology) 2014-03-13 09:30: Genomic technologies (Jason Carroll, Cancer Research UK Cambridge Institute) 2014-03-20 09:30: In vivo models (Suzanne Turner, Department of Pathology) 2014-03-20 13:00: Clinical Systems Medicine in Acute Myeloid Leukemia and Beyond (Olli Kallioniemi, Institute for Molecular Medicine Finland) 2014-04-01 12:00: “Personalized Medicine in Oncology: The Dutch experience” (Professor Jaap Verweij, Erasmus MC Cancer Institute, Weytemaweg 80, 3105 CN Rotterdam, The Netherlands) 2014-04-03 09:30: **Postponed to 19 June** Epidemiology (Paul Pharoah, Department of Public Health and Primary Care) 2014-04-08 12:00: Targeting bioenergetics in hypoxic and rapidly growing tumours (Dr Jacques Pouysseggur, Institute of Research on Cancer and Ageing (IRCAN), Nice, France) 2014-04-09 11:00: Centrosome changes in cancer – causes and consequences (Monica Bettencourt Dias, Instituto Gulbenkian de Ciência) 2014-04-10 09:30: **Postponed to 22 May** Drug discovery (Grahame McKenzie, MRC Cancer Unit) 2014-05-01 09:30: Signal transduction (Ian Mills, Centre for Molecular Medicine Norway) 2014-05-06 12:00: Spatio-temporal control of RhoGTPases and the cytoskeleton in invading cancer cells by integrins and endocytic trafficking (Dr Patrick Caswell, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester) 2014-05-06 13:00: TALK CANCELLED (Joan S Brugge, Harvard Medical School, Cambridge) 2014-05-08 09:30: Therapeutics and clinical trials (Duncan Jodrell, Cancer Research UK Cambridge Institute) 2014-05-13 12:00: "From trials evaluating drugs to trials evaluating treatment algorithms – Focus on the SHIVA trial" (Dr Christophe Le Tourneau, Medical Oncologist, Head of the Phase I Program at the Institut Curie, Paris, France,) 2014-05-20 12:00: Personalised Cancer Medicine. How do we get there? (Dr Helena Earl, Dept. of Oncology, University of Cambridge) 2014-05-22 09:30: Drug discovery (Grahame McKenzie, MRC Cancer Unit) 2014-05-29 09:30: Metabolism, oxygen and cancer (John Griffiths, Cancer Research UK Cambridge Institute) 2014-06-03 12:00: Undermining Myc: Mitochondria Hold the Key (Dr Daniel Murphy, Institute of Cancer Sciences, University of Glasgow) 2014-06-05 09:30: Radiotherapy (Neil Burnet, Department of Oncology) 2014-06-10 12:00: Breast Imaging research in Cambridge (Professor Fiona Gilbert, Head of Department of Radiology, Cambridge) 2014-06-12 09:30: MRI and MRS in cancer research and treatment (John Griffiths, Cancer Research UK Cambridge Institute) 2014-06-19 09:30: Epidemiology (Paul Pharoah, Department of Public Health and Primary Care) 2014-06-24 12:00: Precision Cancer Prevention: Trying to use Genomics to Save Lives (John Hopper, Professor & Director (Research), Centre for Molecular, Environmental, Genetic and Analytic (MEGA) Epidemiology, University of Melbourne, Australia) 2014-06-26 09:30: Epigenetics and microRNA (Eric Miska, Wellcome Trust/Cancer Research UK Gurdon Institute) 2014-06-26 13:00: *New speaker - replaces previously advertised seminar* (Ravid Straussman, Department of Molecular Cell Biology, Weizmann Institute of Science, Israel) 2014-06-27 13:45: Noninvasive cancer genomics (Nitzan Rosenfeld, Cancer Research UK Cambridge Institute) 2014-07-10 13:00: Whole-exome sequencing identifies recurrent functional mutations in melanoma (Yardena Samuels, The Weizmann Institute of Science, Israel) 2014-07-22 12:00: 'Scottish Collaboration On Translational Research into Renal Cell Cancer (SCOTRRCC): a springboard for renal cancer biomarker development’. (Mr Grant Stewart, Clinical Senior Lecturer and Honorary Consultant in Urological Surgery, University of Edinburgh ) 2014-07-28 14:45: Cellular hierarchies in normal and malignant epithelial tissue (John Stingl, Cancer Research UK Cambridge Institute) 2014-09-09 12:00: “Paradigm changes produced by targeted agents in Phase I trials in Oncology. Case studies of a TFbeta inhibitor and a Sonic Hedgehog inhibitor” (Dr Jordi Rodon, Head of Research Unit for Molecular Therapy of Cancer Oncology Department. Vall D’Hebron University Hospital, Barcelona, Spain) 2014-09-18 13:00: The role of macrophages in tumour progression and metastasis (Jeffrey Pollard, University of Edinburgh and Albert Einstein College of Medicine, New York) 2014-10-07 12:00: The role of stem cells in the pathogenesis of hepato-biliary cancers (Professor Nisar Malek, University of Tubingen, Germany) 2014-10-07 12:00: “CDD’s new Research Strategy” (Dr Nigel Blackburn, Director of Centre for Drug Development, Cancer Research UK) 2014-10-14 12:00: CANCELLED - Lung cancer, biomarkers and unanswered questions - a clinical translational perspective (Dr Fiona Blackhall, Consultant Medical Oncologist, The Christie Hospital, Manchester ) 2014-10-16 09:30: Tumour natural history, structure and nomenclature (lecture/demonstration) (Paul Edwards, Department of Pathology) 2014-10-16 13:00: The role of dsRNA in cellular response to genetic change (Andrew Fire, Stanford University) 2014-10-21 12:00: "The role of epigenetic regulators and their therapeutic targeting in Acute Myeloid Leukaemia and haematological malignancies” (Dr Brian Huntly, Department of Haematology, Cambridge University) 2014-10-30 09:30: Overview of cancer theoretical framework (Paul Edwards, Department of Pathology) 2014-11-11 12:00: “Stratified Medicine in Cancer Therapy - a practical guide” (Professor Gary Middleton, Professor in Medical Oncology, School of Cancer Sciences, University of Birmingham) 2014-11-13 09:30: Genetic instability - observation and concepts (Paul Edwards, Department of Pathology) 2014-11-18 12:00: Tracking genomic aberrations of the androgen receptor (AR) in castration-resistant prostate cancer (CRPC) (Dr Gerhardt Attard, Royal Marsden Hospital, London) 2014-11-19 12:00: Cell fate in response to anti-mitotic chemotherapeutics (Professor Stephen Taylor, Faculty of Life Sciences, University of Manchester) 2014-11-20 09:30: Development and the cell cycle (Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre) 2014-11-20 13:00: The use of recent advances in electron microscopy to study the ribosome (Venki Ramakrishnan, MRC Laboratory of Molecular Biology) 2014-11-27 09:30: Transcription (Jason Carroll, Cancer Research UK Cambridge Institute) 2014-12-02 12:00: In vivo function-based genomic approaches for cancer drug target discovery (Professor Daniel Peeper, Head, Division of Molecular Oncology, The Netherlands Cancer Institute) 2014-12-04 09:30: Oncogenes and tumour suppressors (signalling and pathways) (Masashi Narita, Cancer Research UK Cambridge Institute) 2014-12-11 09:30: Tumour Metabolism (Christian Frezza, MRC Cancer Unit) 2014-12-11 13:00: Using RNA-based approaches to identify and characterise cancer genes (Reuven Agami, Netherlands Cancer Institute, Amsterdam) 2014-12-16 12:00: Ovarian Cancer in Transition (Mr Douglas Levine, Gynecology Service, Department of Surgery) 2015-01-13 12:00: Explaining the reduction in ovarian cancer mortality 1977 to 2014 (Dr Steven Narod, Director, Familial Breast Cancer Research Unit, Women's College Research Institute, Toronto, Canada) 2015-01-15 09:30: Metastasis (Sakari Vanharanta, Department of Oncology) 2015-01-22 09:30: Senescence, cell death and apoptosis (Masashi Narita, Cancer Research UK Cambridge Institute) 2015-01-27 12:00: “Optimizing Image Guided Radiotherapy for Patient Benefit” (Dr Peter Remeijer, Medical Physicist NKI /Avl, Amsterdam) 2015-01-29 09:30: Stem cells and cancer (Phil Jones, MRC Cancer Unit) 2015-02-03 12:00: MYC Oncoproteins act as Epigenetic Modifiers (Dr Frank Westermann, Research Group Neuroblastoma Genomics, DKFZ, Heidelberg) 2015-02-05 09:30: Computational biology (Florian Markowetz, Cancer Research UK Cambridge Institute) 2015-02-12 09:30: Computational Biology (Florian Markowetz, Cancer Research UK Cambridge Institute) 2015-02-19 09:30: Genomic technologies (Jason Carroll, Cancer Research UK Cambridge Institute) 2015-02-19 13:00: Cell-specific analysis of tumour-stroma signalling (Dr Claus Jorgensen (CRUK Manchester Institute)) 2015-02-25 09:30: in vivo models (Suzanne Turner, Department of Pathology) 2015-03-03 12:00: Systems Biology of Cancer (Professor Jussi Taipale, Department of Biosciences and Nutrition, Karolinska Institute, Sweden ) 2015-03-05 09:30: Epidemiology (Paul Pharoah, CRUK Genetic Epidemiology Unit, Strangeways Research Laboratory) 2015-03-26 13:00: Towards molecular classification of uterine leiomyomas (Lauri Aaltonen, University of Helsinki, Finland) 2015-04-14 12:00: Defining treatment paradigms in prostate cancer; the UK as a dominant force - past, present, and future (Professor Malcolm Mason, NCRI Prostate Cancer Clinical Studies Group and School of Medicine, Cardiff University) 2015-05-05 12:00: Metastatic Stem Cells, TGF-beta signalling and poor-prognosis in CRC (Dr Eduard Batlle (Group Leader, Institute for Research in Biomedicine, Barcelona)) 2015-05-12 12:00: "Designing trials to find the right dose" (Dr Adrian Mander - Director of MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge) 2015-05-19 12:00: DNA damage response: Mechanisms and relevance for cancer development and treatment (Professor Jiri Bartek, The Danish Cancer Society Research Center Genome Integrity Unit, Denmark) 2015-05-21 13:00: New Roles for Lysine Methylation Signaling in Epigenetic and Cancer Regulation (Or Gozani, Stanford University, California) 2015-06-02 12:00: 'ECM remodelling during cancer progression' (Dr Janine Erler, Associate Professor - Biotech Research & Innovation Centre (BRIC),Copenhagen ) 2015-06-09 12:00: 'Harnessing hypoxia signalling in cancer' (Professor Margaret Ashcroft, Cambridge Cardiovascular) 2015-06-18 13:00: From Bioinformatics to Drug Discovery and Clinical Trials: Targeting Tumour Metabolism To Eradicate Cancer Stem Cells (Michael Lisanti, Institute of Cancer Sciences, Manchester) 2015-06-23 12:00: Interrogating the Architecture of Cancer Genomes (Dr Peter Campbell, Head of Cancer Genome Project, Wellcome Trust Sanger Institute.) 2015-07-07 11:00: ‘Novel dual-action combination therapy enhances angiogenesis whilst reducing tumour growth and spread’ (Professor Kairbaan Hodivala-Dilke, Professor of Angiogenesis, Deputy Institute Director QMUL ) 2015-09-08 12:00: CANCELLED - "Synergistic effect of radiotherapy and cis-platinum chemotherapy delivered via gold nanoparticles in glioblastoma multiforme" (Dr Sara Piccirillo, Department of Clinical Neurosciences and Alexandra Vaideanu, Deptatment of Engineering ) 2015-09-15 12:00: Genomics of radiation responses and radiosensitivity (Professor Michael McKay, North Coast Cancer Institute, NSW, Australia) 2015-09-24 13:00: Genotypic Variability and the Quantitative Proteotype (Ruedi Aebersold; ETH, Zurich) 2015-10-13 12:00: Melanoma and the translational cycle of innovation in cancer therapeutics (Professor Grant McArthur, Peter MacCallum Cancer Centre, Victoria, Australia) 2015-10-15 09:30: This talk has been postponed (Speaker to be confirmed) 2015-10-29 09:30: Tumour natural history, structure and nomenclature (Paul Edwards, Department of Pathology) 2015-10-29 13:00: Imaging and targeting cancer; the multitasking Focal Adhesion Kinase controls cancer cell polarization and immune evasion (Margaret Frame; Edinburgh Cancer Research Centre) 2015-11-05 09:30: Overview of cancer theoretical framework (Paul Edwards, Department of Pathology) 2015-11-17 11:30: Intrinsic and extrinsic determinants of pancreatic cancer stem cells (Professor Christopher Heeschen, Centre Lead, Centre for Stem Cells in Cancer and Ageing, Barts Cancer Institute, London) 2015-11-19 09:30: This talk is postponed until Dec 16 (Speaker to be confirmed) 2015-11-19 13:00: Origins and clonal evolution of childhood leukaemia (Tariq Enver; University College London) 2015-11-24 12:00: "Tumor-­induced reprogramming of hepatic metabolism disrupts anti‐tumor immunity” (Dr Tobias Janowitz, Department of Oncology) 2015-11-26 09:30: Tumour natural history, structure and nomenclature (Paul Edwards, Department of Pathology) 2015-12-03 09:30: Title to be confirmed (Speaker to be confirmed) 2015-12-08 12:00: ‘Combine and conquer: critical pre-clinical and clinical aspects of targeted anti-cancer drugs’ (Dr Udai Banerji, Drug Development Unit, ICR) 2015-12-10 09:30: Reproducible Research (Florian Markowetz, CRUK CI) 2015-12-18 13:00: RASA2 is a Novel Tumor Suppressor in Melanoma (Yardena Samuels; Weizmann Institute, Israel) 2016-01-14 09:30: Colorectal cancer and its management (Dr Simon Buczacki) 2016-01-21 09:30: Oesophageal cancer (Professor Rebecca Fitzgerald) 2016-01-21 13:00: Proteomics in cell signaling and cancer research (Matthias Mann, Max-Planck Institute of Biochemistry, Munich and Novo Nordisk Foundation Center for Protein Research, Copenhagen) 2016-01-28 09:30: Cancer metastasis (Dr Sakari Vanharanta) 2016-02-04 09:30: Leukaemia (Dr Brian Huntly) 2016-02-11 09:30: Ovarian cancer (Dr Christine Parkinson) 2016-02-18 09:30: Brain cancer (Professor Richard Gilbertson) 2016-02-18 13:00: DNMT3A in Hematopoietic Stem Cells, Cancer and Ageing (Margaret A. Goodell, Baylor College of Medicine, Houston) 2016-02-23 12:00: Innate Genetics and the Tumour Microenvironment Cooperate to Drive Prostate Cancer Aggression (Prof Robert G Bristow, Senior Scientist, Princess Margaret Cancer Centre, Toronto) 2016-03-09 17:00: “New Developments in Molecular Imaging of Prostate Cancer” (Professor Wim Oyen, Professor of Nuclear Medicine and Molecular Imaging, ICR, London) 2016-03-10 09:30: Prostate cancer (Dr Vincent Gnanapragasam) 2016-03-15 12:00: “Why Determining Pathogenicity in the Age of Precision Medicine, will Require More than Analyzing Genomic Sequences” (Dr Bruce Gottlieb, Lady Davis Institute for Medical Research, Segal Cancer Centre, Jewish General Hospital, Department of Human Genetics, Department of Medicine, McGill University, Montreal, Canada) 2016-03-17 09:30: Breast cancer (Professor Carlos Caldas) 2016-03-22 13:00: Tumour suppressor and tumour maintenance genes (Scott Lowe, Memorial Sloan Kettering Cancer Centre, New York) 2016-04-14 09:30: DNA damage repair (Dr Mark O'Connor, AstraZeneca) 2016-04-14 13:00: Understanding and targeting the ovarian cancer microenvironment (Fran Balkwill, Queen Mary University of London) 2016-04-21 09:30: Use of surgery in breast cancer treatment (Mr Parto Forouhi, Cambridge University Hospitals) 2016-04-28 09:30: Treatment of pancreatic cancer (Professor Duncan Jodrell, CRUK CI and Cambridge University Hospitals) 2016-05-03 11:30: “Mechanisms of MYC-driven genome instability” (Jean Gautier, Professor of Genetic and Development, Institute for Cancer Genetics, Columbia University, New York (USA)) 2016-05-12 09:30: Treatment of lung cancer (Dr Susan Harden, Cambridge University Hospitals) 2016-05-17 12:00: Future of medicines development: capabilities and how industry is evolving and interacting with academia and the NHS (Andrew Hughes, Professor of Experimental Cancer Medicine,The Christie NHS Foundation Trust, Manchester) 2016-05-19 09:30: Cancer immunotherapy (Dr Robert Wilkinson, MedImmune) 2016-05-19 13:00: *Please note that this talk has been cancelled and re-scheduled for 2017* (Shelley Berger, University of Pennsylvania) 2016-06-02 09:30: Surgery and prostate cancer (Mr Adam Nelson, CRUK CI and Cambridge University Hospitals) 2016-06-09 09:30: Comparative aspects of canine cancer and therapy (Dr Jane Dobson, Dept of Veterinary Medicine, University of Cambridge) 2016-06-09 12:30: Computational Radiotherapy Symposium, 2016: personalised radiotherapy, or how computers can cure cancer (Speakers as detailed in Symposium Programme) 2016-06-16 09:30: Common germline genetic variation and risk of cancer (Professor Paul Pharoah, Dept of Oncology, University of Cambridge) 2016-06-28 12:00: Mechanisms of lymphomagenesis: Developmental origins of a paediatric cancer (Dr Suzanne Turner, Department of Pathology) 2016-06-30 13:00: Using Mouse Models to Understand Metastatic Spread and Tumour Heterogeneity (Ben Stanger, Perelman School of Medicine, University of Pennsylvania) 2016-07-05 11:30: "Mechanisms of colon cancer initiation, progression and metastasis" (Joerg Huelsken, Associate Professor, Debiopharm Chair in Signal Transduction in Oncogenesis, EPFL, Lausanne) 2016-09-15 13:00: *Please note that this talk has been cancelled* (Nancy Jenkins, Houston Methodist Centre, Texas) 2016-09-23 13:00: Studies into the biology of metastatic disease reveals tRNA-derived fragments that suppress cancer progression (Sohail Tavazoie, The Rockefeller University, New York) 2016-10-13 13:00: SEMINAR CANCELLED (Bob Darnell, Rockefeller University, New York and Howard Hughes Medical Institute) 2016-11-17 13:00: The Cancer Cell Map Initiative (Trey Ideker, UC San Diego School of Medicine, La Jolla, CA) 2016-11-29 12:00: CANCELLED - Impact of the Microbiome on cancer and its treatment (Dr Trevor Lawley, Group Leader, Host-Microbiota Interactions Laboratory, Wellcome Trust Sanger Institute) 2016-12-15 13:00: What can we learn from Cancer Genomes? (Gad A. Getz, Ph.D, Massachusetts General Hospital Cancer Center and Broad Institute of MIT & Harvard) 2017-01-19 13:00: Overcoming Chromatin Barriers to Elicit Cell Fate Changes (Ken Zaret, Joseph Leidy Professor, Perelman School of Medicine, University of Pennsylvania) 2017-02-07 11:30: The interaction between tumor hypoxia and DNA methylation (Dr Bernard Thienpont, VIB-KU Leuven Center for Cancer Biology, KU Leuven, Belgium) 2017-02-23 16:00: Epigenomic pathways in cancer and in cancer immunotherapy (Shelley Berger, Epigenetics Institute, Departments of Cell and Developmental Biology, Genetics, Biology, University of Pennsylvania) 2017-03-07 11:30: ‘Non-coding RNA - new roles for old players’ (Professor Anders Lund, Biotech Research and Innovation Centre, University of Copenhagen) 2017-03-16 13:00: *PLEASE NOTE THAT THIS TALK HAS BEEN CANCELLED* (Johanna Ivaska, Turku Centre for Biotechnology, Finland) 2017-05-02 11:30: ‘Alterations of the Polycomb machinery in cancers’ (Raphaël Margueron, Curie Institute, Paris) 2017-05-04 13:00: Switching Genes on and off in Erythropoiesis (Doug Higgs, University of Oxford) 2017-05-25 13:00: MYC and Metabolic Vulnerabilities of Cancer (Chi Van Dang, MD, PhD, Professor and Director, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine) 2017-05-25 15:00: 'Analyses for Rule-Based Models of Cellular Signalling' (Dr Jean Yang, Assistant Professor,Department of Computer Science, Carnegie Mellon University, Pittsburgh USA ) 2017-06-06 11:30: ‘Exploring and exploiting aberrant self-fate programs in leukemia’ (Dr Johannes Zuber, Research Institute of Molecular Pathology (IMP), Vienna, Austria) 2017-06-15 13:00: ****CANCELLED***Mammalian SWI/SNF (BAF) complex structure and function in human cancer (Cigall Kadoch, Ph.D, Dana- Farber Cancer Institute and Harvard Medical School, Boston) 2017-06-26 15:00: Satellite RNAs, Heterochromatin and Cancer: A Novel Mechanism of Induction of Breast Cancer by Loss of BRCA1? (Professor Inder Verma, Salk Institute, San Diego, USA ) 2017-09-18 14:00: ‘The role of Mre11 in DNA double strand break repair - myth and facts’ (Professor Shunichi Takeda, Department of Radiation Genetics, Kyoto University) 2017-09-21 13:00: ***PLEASE NOTE THIS SEMINAR IS CANCELLED*** (Liz Jaffee, Johns Hopkins Medical Institute, USA) 2017-10-12 13:00: Biomolecular condensates and their implications for neurodegenerative disease (Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden) 2017-11-02 09:30: Tumour structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Bioloy) 2017-11-07 11:30: Metastasis latency: new molecular insights (Roger Gomis, ICREA Research Professor, IRB Barcelona) 2017-11-09 09:30: Overview of the core ideas in cancer research (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2017-11-16 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2017-11-16 13:00: Genomic Approaches to Cancer (Todd Golub, Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute) 2017-11-23 09:30: Cancer metabolism - a hallmark of cancer (Dr Christian Frezza, MRC Cancer Unit) 2017-11-30 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology) 2017-12-05 11:30: ‘Tracking metabolic reprogramming in cancers with PI3K/Akt activation’ (George Poulogiannis, Team Leader, Division of Cancer Biology, Institute of Cancer Research, London) 2017-12-14 09:30: DNA repair: from mechanistic insights to therapeutic applications in cancer (Professor Steve Jackson, The Gurdon Institute) 2017-12-14 13:00: Dangerous Liaisons between platelets and cancer (Anil Sood, MD - University of Texas, MD Anderson Cancer Centre) 2018-01-18 13:00: Mechanosensing and endosomal traffic – new vulnerabilities in breast cancer (Johanna Ivaska, Turku Centre for Biotechnology, University of Turku, Finland) 2018-02-06 14:30: Oxidative Stress Defences in Cancer (Professor Joan Brugge, Louise Foote Pfeiffer Professor of Cell Biology and Director of the Ludwig Centre at Harvard University) 2018-02-22 09:30: Introduction to early detection and tumour development (Professor Paul Pharoah and Dr Jamie Blundell, Early Detection Programme) 2018-03-06 11:30: ‘Instituting Molecular Precision in Localised Prostate Cancer - A Cure for All?’ (Rob Bristow, University Professor of Cancer Studies, Director of MCRC) 2018-03-08 09:30: Imaging techniques and novel tools for early detection and intervention (Dr Sarah Bohndiek and Dr Daniel Munoz-Espin, Early Detection Programme) 2018-03-15 09:30: TALK CANCELLED Targets for drug discovery: from target validation to the clinic (Dr Paul Smith, AstraZeneca) 2018-03-15 13:00: Transcription Factor/Chromatin Interactions: Integrating Genomics and Live Cell Dynamics (Gordon Hager, National Cancer Institute Centre for Cancer Research, USA) 2018-03-20 12:00: "Proton Beam Therapy: Current and Future Provision" (Yen-Ching Chang, Consultant in Clinical Oncology, UCHL) 2018-04-12 09:30: Breast cancer - demographics, presentation, diagnosis and patient pathway (Dr Charlotte Coles, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust) 2018-04-12 13:00: RNA Genomics in Health and Disease (Robert B Darnell, MD PhD, The Rockefeller University and Howard Hughes Medical Institute) 2018-04-19 09:30: Demographics, presentation, diagnosis and patient pathway of haematological malignancies (Professor Brian Huntly, Department of Haematology) 2018-04-19 13:00: Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain (Joseph R Ecker PhD, The Salk Institute for Biological Studies, La Jolla, CA) 2018-05-03 09:30: Translational Science: using biomarkers to guide clinical development in oncology (Dr Andy Pierce, AstraZeneca) 2018-05-03 11:00: ‘Accelerating the translation of mutational signatures' (Dr Serena Nik-Zainal, Wellcome Sanger Institute) 2018-05-17 13:00: Clonal evolution of cancer: lessons from the mouse (Allan Balmain, UCSF Helen Diller Comprehensive Family Cancer Centre) 2018-05-31 09:30: 5 selfish reasons to work reproducibly (Dr Florian Markowetz, Group Leader, Cancer Research UK Cambridge Institute, University of Cambridge) 2018-06-05 11:00: ‘Cellular Plasticity in Cancer: driving force and therapeutic target’ (Professor Thomas Brabletz, Department of Experimental Medicine, University Erlangen-Nuernberg) 2018-06-14 09:30: Paediatric malignancies: an overview (Dr Amos Burke, Department of Paediatric Haematology, Oncology and Palliative Care, Cambridge University Hospitals NHS Foundation Trust) 2018-06-15 10:30: ‘Nuclear Mechanopathology & Early Cancer Diagnostics’ (Professor GS Shivashankar, Deputy Director, Mechanobiology Institute, National University of Singapore) 2018-06-21 09:30: Frontiers in paediatric cancer research (Dr Suzanne Turner, Department of Pathology) 2018-06-28 09:30: Colorectal cancer. Part 1. Presentation, Diagnosis and Intervention. Part 2. Cellular signalling networks in colon cancer and the models to study them - a basic research perspective (Mr Simon Buczacki, CRUK Cambridge Institute and Dr Marc de la Roche, Department of Biochemistry) 2018-06-28 13:00: Functional Genomics to Study Cancer (David Sabatini, Whitehead Institute) 2018-07-05 09:00: Lung Cancer. Part 1. Patient pathway and Intervention. Part 2. Lung Cancer: Futurescape (Dr Robert Rintoul, CUH and Papworth NHS Foundation Trusts, and Dr Frank McCaughan, Department of Biochemistry) 2018-07-10 13:00: Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer (Cigall Kadoch, Dana-Farber Cancer Institute and Harvard Medical School) 2018-07-12 09:30: Diagnostics and patient pathways in pancreatic cancer (Mr Raaj Praseedom, Cambridge University Hospitals NHS Foundation Trust) 2018-07-19 09:30: Research frontiers and new therapeutic strategies in pancreatic cancer (Dr Tobias Janowitz, Department of Oncology) 2018-07-26 09:30: MicroRNAs as circulating biomarkers in cancer (Dr Matthew Murray, Department of Pathology) 2018-09-27 13:00: *** Cancelled*** (Ana Pombo, MDC Berlin) 2018-10-25 13:00: Towards cancer screening using circulating DNA (Y M Dennis Lo, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China) 2018-11-15 13:00: Bridging DNA methylation dynamics and electronic health records to understand the non-coding genome (Emily Hodges, Vanderbilt Genetics Institute, USA) 2018-11-29 09:30: Introduction to the biology of metastasis (Dr Sakari Vanharanta, MRC Cancer Unit ) 2018-12-04 11:30: ‘Executable Disease Networks: Reconstruction, Topology, Dynamics’ (Anna Niarakis, Université Paris-Saclay, Evry, France) 2019-01-03 09:30: The integrated approach to the diagnosis of haematological malignancies (Dr Mike Scott, Department of Haematology, Cambridge University Hospitals NHS Foundation Trust) 2019-01-15 11:30: THIS SEMIAR IS NOW CANCELLED - 'Cell Plasticity in Colon Carcinogenesis' (Professor Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frankfurt) 2019-01-17 09:30: Systemic Anticancer Therapy (Dr Bristi Basu, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust) 2019-01-31 13:00: Genome Architecture Mapping: discovering 3D genome topology in rare cell types (Ana Pombo, Berlin Institute for Medical Systems Biology, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Humboldt University of Berlin, Berlin, Germany) 2019-02-07 09:30: Lecture Cancelled (Louisa Bellis (University of Cambridge)) 2019-02-21 13:00: Epigenetic control of malignant melanoma (Emily Bernstein, Icahn School of Medicine at Mount Sinai) 2019-02-27 12:00: ‘Multi-dimensional cancer-immune cell interaction during metastasis’ (Xiang Zhang, Baylor College of Medicine, Houston, USA) 2019-02-28 09:30: Liquid biopsy biomarkers for early detection; general principles and specific examples (Dr Charlie Massie, Early Detection Programme) 2019-03-14 09:30: Lecture Cancelled (Lecture Cancelled) 2019-03-21 09:30: Demographics, Diagnosis and Treatment Pathways in Haematological Malignancies (Professor Brian Huntly, Department of Haematology) 2019-03-21 13:00: A Deep Dive into the Genome of Hypoxic Tumours (Robert Bristow, Manchester Cancer Research Research Centre, University of Manchester) 2019-03-28 09:30: The bone marrow microenvironment in myeloid malignancies (Dr Simon Mendez-Ferrer (University of Cambridge)) 2019-04-09 11:30: ‘Mammary epithelial cell fate and tumour initiation at the single cell resolution’ (Walid Khaled, Department of Pharmacology, University of Cambridge) 2019-04-11 13:00: Fire and Water are Good Servants, But Bad Masters (Tak Mak, Princess Margaret Cancer Centre, University Health Network, University of Toronto) 2019-04-26 13:00: Cellular Conversations that Control Cancer (Thea D Tlsty, University of California San Francisco (UCSF) Helen Diller Comprehensive Cancer Center and Department of Pathology, 513 Parnassus Avenue, San Francisco, CA 94143-0511) 2019-05-07 11:30: ‘New protagonists of the tumour microenvironment’ (Dr Ilaria Malanchi, Tumour-Host Interaction Lab,Francis Crick Institute, London ) 2019-05-09 09:30: Kidney cancer: the most lethal urological malignancy (Dr Grant Stewart, Department of Surgery, Cambridge University Hospitals NHS Foundation Trust) 2019-05-30 09:30: Brain tumours: demographics, presentation, diagnosis, treatment (Mr Thomas Santarius, Cambridge University Hospitals NHS Foundation Trust) 2019-06-11 11:30: ‘Next-Generation Biopsies in Gastrointestinal Cancers’ (Dr Nicola Valeri, Institute of Cancer Research and The Royal Marsden NHS Trust) 2019-06-11 12:00: ‘Why Standard Naming and Pixel-based Contouring/Voluming are important to research in the radiation Oncology area’ (Prof Andrew Miller, Radiation Oncologist, Illawarra Cancer Care Centre, Wollongong, NSW Australia / Adjunct Professor of Informatics, School of Informatics, University of Wollongong ) 2019-06-20 09:30: The childhood cancer genome (Dr Sam Behjati - Research Fellow in Medical Sciences and Wellcome Trust Intermediate Clinical Fellow, Department of Paediatrics and WTSI) 2019-06-20 13:00: Perturbation biology: data-driven executable models of cellular processes and the design of combination therapy (Chris Sander, Dana-Farber Cancer Institute and Harvard Medical School) 2019-06-27 09:30: Cellular signalling networks in colon cancer and the models to study them. A basic research perspective (Dr Marc de la Roche, Lecturer - Department of Biochemistry) 2019-07-01 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Institute for Tumor Biology and Experimental Therapy Frankfurt) 2019-07-10 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Heidelberg University, Faculty of Medicine & EMBL- Heidelberg University Molecular Medicine Partnership Unit) 2019-07-11 09:30: Diagnostics and patient pathways in pancreatic cancer (Dr Raaj Praseedom - Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team.) 2019-07-25 09:30: MicroRNAs as circulating biomarkers in cancer (Dr Matthew Murray - Academic Consultant Paediatric Oncologist) 2019-09-03 11:30: ‘Treatment of cancer by inhibition of mtDNA gene expression’ (Nils-Göran Larsson, MD, PhD, Professor, Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm ) 2019-09-26 13:00: TET-family dioxygenases, immune responses and cancer (Anjana Rao, La Jolla Institute for Allergy and Immunology) 2019-10-01 11:30: ‘Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis’ (Professor Albena Dinkova-Kostova,Jacqui Wood Cancer Centre, Division of Cellular Medicine, University of Dundee ) 2019-10-11 13:00: Transcriptional dependencies in cancer (Christopher Vakoc, Cold Spring Harbor Laboratory) 2019-10-24 09:30: Tumour structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2019-10-31 09:30: Overview of the core ideas in cancer research (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2019-10-31 13:00: Forcing tumor initiation and progression (Valerie M Weaver, University of California, San Francisco) 2019-11-07 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2019-11-14 09:30: Introduction to the biology of metastasis (Dr Sakari Vanharanta, MRC Cancer Unit) 2019-11-21 09:00: Cancer metabolism, a hallmark of cancer- NB 9am start time (Dr Christian Frezza, MRC Cancer Unit) 2019-11-21 13:00: Cancer and ageing: Rival demons? (Judith Campisi, Buck Institute for Research on Ageing and Lawrence Berkeley National Laboratory) 2019-11-28 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology) 2019-12-03 11:30: ‘Cell Plasticity in Colon Carcinogenesis’ (Professor Dr Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frakfurt) 2019-12-12 09:30: Exploring the role of the tumour microenvironment: what do other cells do? (Dr Jacqui Shields - MRC Cancer Unit) 2020-01-09 10:00: Systemic anticancer therapy (Dr Gary Doherty (University of Cambridge)) 2020-01-16 09:30: Cancer Immunotherapy (Dr Christine Parkinson, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust) 2020-01-23 09:30: A scientists guide to the art of radiation therapy & Neurosurgery for the Oncologist (Dr Raj Jena, Department of Onocology and Mr Adel Helmy, Department of Clinical Neuroscience CUH NHS Foundation Trust) 2020-02-04 13:00: Single cell whole genome sequencing approaches to model evolution in cancer (Sohrab Shah, MSKCC) 2020-02-13 09:30: The AKT inhibitor Capivasertib (AZD5363): From Discovery to Clinical Proof of Concept (Dr Barry Davies - Director, Clinical and Translational Scientific Alliances, AstraZeneca) 2020-02-20 09:30: The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway (Dr Simon Cook, Babraham Institute) 2020-02-27 09:30: Oncological Imaging: introduction and non-radionuclide techniques & radionuclide techniques (Dr. Ferdia Gallagher Department of Radiology & Dr Luigi Aloj, Department of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust) 2020-03-05 09:30: Introduction to the early detection of cancer and novel interventions (Professor Rebecca Fitzgerald, Early Detection Programme) 2020-03-12 09:30: The development of cancer risk susceptibility models and application to early detection (Professor Antonis Antoniou, Early Detection Programme) 2020-03-19 09:30: Biological and Clinical Features of High Grade Serous Ovarian Cancer (Dr James Brenton, CRUK Cambridge Institute) 2020-03-26 09:30: Breast cancer: demographics, presentation, diagnosis & patient pathway (Dr Richard Baird, Department of Oncology) 2020-04-02 09:30: The microenvironment in the myeloid malignancies (Dr Simon Mendez-Ferrer, Department of Haematology) 2020-04-07 11:30: CANCELLED - “Cancer genomics: from chromatin structure to new therapeutic targets” (Professor Elisa Oricchio (EPFL, Zurich)) 2020-04-09 09:30: DNA repair: from mechanistic insights to therapeutic applications in cancer (Professor Steve Jackson, The Gurdon Institute) 2020-04-23 09:30: Mathematical and evolutionary approaches to cancer (Jamie Blundell, Early Detection Programme, Dept of Oncology) 2020-04-23 13:00: **** This seminar has been cancelled **** (Jim Norman, Cancer Research UK Beatson Institute) 2020-04-30 09:30: Epidemiology of Ovarian Cancer (Professor Paul Pharoah, Professor of Genetic Epidemiology ) 2020-05-07 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute) 2020-05-14 09:30: Treatment of kidney cancer (Mr Grant Stewart, Cambridge University Hospitals) 2020-05-21 09:30: Paediatric Malignancies (Dr Amos Burke, Clinical Consultant - Department of Paediatric Haematology, Oncology and Palliative Care) 2020-05-21 13:00: **** This seminar has been cancelled **** (Ramanujan S Hegde) 2020-05-28 09:30: Artificial Intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities (Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute) 2020-06-04 09:30: The clinical and biological basis of prostate cancer - from diagnosis to personalised therapy (Mr Vincent Gnanapragasam, Department of Surgery, Cambridge University Hospitals NHS Foundation Trust) 2020-06-11 09:30: The promise of proton therapy in Paediatric tumours (Dr Thankamma Ajithkumar, Cambridge University Hospitals NHS Foundation Trust) 2020-06-18 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Munoz-Espin, Group Leader, Department of Oncology.) 2020-06-25 09:30: Lung Cancer: Part 1. Patient pathway and intervention. Part 2. Lung Cancer: Futurescape (Dr Robert Rintoul -Clinical Consultant, Cancer Research UK Cambridge Institute and Dr Frank McCaughan-Wellcome Trust Intermediate Clinical Fellow / Honorary Consultant,Department of Biochemistry School of Clinical Medicine ) 2020-06-25 13:00: **** This seminar has been cancelled **** (Marica Haigis, Harvard Medical School) 2020-07-02 09:30: The biology and fundamental management of colorectal cancer (Mr Simon Buczacki, Dept Haematology (University of Cambridge)) 2020-07-09 09:30: Viral Oncology (Professor John Doorbar, Department of Pathology) 2020-07-16 09:30: Diagnostics and patient pathways in pancreatic cancer ( Mr Raaj Praseedom, Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team) 2020-09-17 17:30: Therapeutic Opportunities in Glycoscience (Carolyn Bertozzi, Stanford University) 2020-10-15 13:00: Targeting the Tumour Microenvironment (Clare Isacke, The Institute of Cancer Research) 2020-10-22 09:30: Tumour structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2020-10-29 09:30: Overview of the core ideas in cancer research (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2020-11-05 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2020-11-12 09:30: Introduction to the biology of metastasis (Dr Sakari Vanharanta, MRC Cancer Unit ) 2020-11-19 09:30: Cancer metabolism, a hallmark of cancer (Dr Christian Frezza, MRC Cancer Unit) 2020-11-19 13:00: The remote control of gene expression: enhancer function in development and disease (Wendy Bickmore, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh) 2020-11-26 09:30: DNA repair: from mechanistic insights to therapeutic applications in cancer (Professor Steve Jackson, The Gurdon Institute) 2020-12-03 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology) 2020-12-10 09:30: Exploring the role of the tumour microenvironment: what do the other cells do? (Dr Jacqui Shields, MRC Cancer Unit) 2020-12-17 10:00: Systemic anti-cancer therapy (Dr Gary Doherty, Cambridge University Hospital NHS Foundation Trust) 2021-01-07 09:30: The bone marrow microenvironment in myeloid malignancies (Dr Simón Méndez-Ferrer, Department of Haematology) 2021-01-14 09:30: Cancer Immunotherapy (Dr Christine Parkinson, Dept of Oncology, CUH NHS Foundation Trust) 2021-01-21 09:30: A scientist’s guide to the art of radiation therapy & Neurosurgery for the Oncologist (Dr Raj Jena, Dept of Oncology & Mr Adel Helmy, Dept of Clinical Neuroscience, CUH NHS Foundation Trust) 2021-01-21 13:00: Molecular Imaging for the Improved Visualization and Treatment of Cancer (Jason Lewis, MSKCC) 2021-01-28 09:30: Clinical treatment and cancer stem cell biology in malignant glioma (Dr Harry Bulstrode, Dept of Clinical Neuroscience, CUH NHS Foundation Trust) 2021-02-11 09:30: The AKT inhibitor capivasertib (AZD5363): from discovery to clinical proof concept (Dr Barry Davies, Director, Clinical Translation Scientific Alliances, AstraZeneca) 2021-02-18 09:30: The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway (Dr Simon Cook FRSB, Senior Group Leader, Babraham Institute) 2021-02-25 09:30: Oncological Imaging: i. Introduction & Non-radionuclide techniques ii. Radionuclide techniques (Prof Ferdia Gallagher, Dept of Radiology, & Dr Luigi Aloj, Dept of Nuclear Medicine, CUH NHS Foundation Trust) 2021-02-25 13:00: Mechanisms and consequences of pancreatic cancer stromal evolution (Mara Sherman, Oregon Health & Science University) 2021-03-04 09:30: Mathematical and evolutionary approaches to cancer (Dr Jamie Blundell, Early Detection Programme, Dept of Oncology) 2021-03-11 09:30: Early detection and treatment of lethal prostate cancer. (Dr Charlie Massie, Dept of Oncology and Dr Harveer Dev, Clinical Lecturer Early Detection Programme) 2021-03-18 09:30: Paediatric malignancies: an overview (Dr Amos Burk Clinical Consultant, Dept of Paediatric Haematology, Oncology and Palliative Care) 2021-03-18 13:00: Regulation of Protein Degradation in Cancer and Effect on Tumor Immunity (X. Shirley Liu, Dana-Farber Cancer Institute and Harvard University ) 2021-03-25 09:30: Breast Cancer – demographics, presentation, diagnosis and patient pathway (Dr Richard Baird, Dept of Oncology, CUH NHS Foundation Trust) 2021-04-15 09:30: Lung Cancer. Part 1. Patient pathway and Intervention; Part 2: Futurescape (Dr Robert Rintoul, Royal Papworth Hospital NHS Foundation Trust and Dr Frank McCaughan, Wellcome Trust Intermediate Clinical Fellow, Dept of Biochemistry) 2021-04-22 09:30: Epidemiology of Ovarian Cancer (Professor Paul Pharoah, Centre for Cancer Genetic Epidemiology) 2021-04-29 09:30: The role of transcription factors in cancer ( Dr Jason Carroll, CRUK Cambridge Institute) 2021-05-06 09:30: Artificial intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities. (Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute) 2021-05-13 09:30: Kidney cancer: the most lethal urological malignancy (Prof Grant Stewart, Dept of Surgery, Cambridge University Hospitals NHS Foundation Trust) 2021-05-20 09:30: Frontiers in paediatric cancer research (Dr Suzanne Turner, Dept of Pathology, Cambridge University) 2021-05-20 13:00: Quality control of proteins orphaned in the cytosol (Ramanujan S Hegde, MRC LMB) 2021-05-27 09:30: The promise of proton therapy in paediatric tumours (Dr Thankamma Ajithkumar, Consultant Clinical Oncologist, Cambridge University Hospitals NHS Foundation Trust) 2021-06-03 09:30: Biological and clinical features of high grade serous ovarian cancer ( Dr James Brenton, CRUK Cambridge Institute) 2021-06-10 09:30: Understanding Myc transcription (Dr Cathy Wilson, Department of Pharmacology) 2021-06-17 09:30: Diagnostics and patient pathways in pancreatic cancer ( Mr Raaj Praseedom, Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team) 2021-06-17 13:00: Cancelled (Marcia Haigis, Harvard Medical School) 2021-06-24 09:30: It takes a village: targeting the non-cancerous neighbours to fight pancreatic cancer (Dr Giulia Biffi; Cancer Research UK Cambridge Institute) 2021-07-01 09:30: In vivo functional screens for modelling cancer initiation and progression (Dr Eric Rahrmann, Cancer Research UK Cambridge Institute) 2021-07-15 09:30: From another lens: An anthropological perspective on cancer and care in the UK. (Dr Ignacia Arteaga Dept of Social Anthropology ) 2021-07-22 09:30: Viral Oncology (Professor John Doorbar, Department of Pathology) 2021-09-02 13:00: Cancelled (Nikolaus Rajewsky, MDC Berlin) 2021-09-16 13:00: Cell Polarity and Organoids: New Pathways and Models for Translational Research and Cancer Immunology (Senthil Muthuswamy, Harvard Medical School) 2021-10-14 15:00: Priming the Immune System to Provoke Checkpoints: The Path to Maintaining the Immunotherapy Momentum (Elizabeth M Jaffee, John Hopkins) 2021-10-21 09:30: Tumour structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2021-10-28 09:30: Overview of the core ideas in cancer research (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2021-10-29 13:00: Metabolic rewiring drives invasion and metastasis in mammary carcinoma (Jim Norman, Cancer Research UK Beatson Institute) 2021-11-04 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2021-11-11 09:30: Introduction to the biology of metastasis (Dr Sakari Vanharanta, MRC Cancer Unit) 2021-11-18 09:30: Systematic anti-cancer therapy ( Dr Gary Doherty, CUH NHS Foundation Trust) 2021-11-18 13:00: Seminar cancelled (Amos Tanay, Weizmann Institute of Science) 2021-11-25 09:30: DNA repair: translating mechanistic insights towards new cancer therapies. (Professor Steve Jackson, The Gurdon Institute ) 2021-12-02 09:30: Care and Cure:an Introduction to Philosophy of Medicine (Professor Jacob Stegenga, Department of History and Philosophy of Science:) 2021-12-09 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology) 2021-12-16 09:30: Oncological imaging: 1: Introduction and non-radionuclide techniques; 2: Radionuclide techniques (Prof Ferdia Gallagher, Department of Radiology (Cambridge University) & Dr Luigi Aloj, Department of Nuclear Medicine, (Cambridge University Hospitals)) 2021-12-16 13:00: Decoding and Recoding the Opposing Roles of Interferon and Pattern Recognition Receptor Signaling in Cancer Immunotherapy (Andy J. Minn, MD, PhD, Abramson Family Cancer Research Institute at the University of Pennsylvania) 2022-01-06 09:30: A scientist’s guide to the art of radiation therapy & Neurosurgery for the Oncologist (Dr Raj Jena, Dept of Oncology & Mr Adel Helmy, Dept of Clinical Neuroscience (CUH NHS Foundation Trust)) 2022-01-13 09:30: Viral Oncology (Professor John Doorbar, Department of Pathology) 2022-01-20 09:30: Mathematical and evolutionary approaches to cancer (Dr Jamie Blundell, Early Detection Programme, Dept of Oncology ) 2022-02-17 09:30: The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway (Dr Simon Cook FRSB, Senior Group Leader, Babraham Institute) 2022-02-24 09:30: Artificial Intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities (Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute) 2022-03-03 09:30: Breast Cancer- demographics, presentation, diagnosis and patient pathway (Dr Richard Baird, Dept of Oncology, CUH NHS Foundation Trust) 2022-03-10 09:30: Paediatric malignancies - an overview (Dr Amos Burk Clinical Consultant, Dept of Paediatric Haematology, Oncology & Palliative Care) 2022-03-17 09:30: The bone marrow microenvironment in myeloid malignancies (Dr Simon Mendez-Ferrer Dept of Haematology, Cambridge Stem Cell Institute) 2022-03-17 13:00: Title to be confirmed (Karen Vousden, The Crick Institute) 2022-03-24 09:30: Epidemiology of Ovarian Cancer (Prof Paul Pharoah, Centre for Cancer Genetic Epidemiology) 2022-03-31 09:30: In vivo functional screens for modelling cancer initiation and progression (Dr Eric Rahrmann, Cancer Research UK Cambridge Institute) 2022-04-01 13:00: Deciphering the regulation and regulatory function of oncogenic transcription factors using time-resolved functional genetics (Johannes Zuber, IMP, Vienna BioCentre) 2022-04-07 09:30: Biological and Clinical features of high grade serous ovarian cancer (Dr James Brenton, CRUK Cambridge Institute) 2022-04-28 09:30: The role of transcription factors in cancer (Dr Jason Carroll; CRUK Cambridge Institute) 2022-04-28 13:00: Title to be confirmed (Fatima Metcha-Grigoriou, Institut Curie) 2022-05-05 09:30: The promise of proton therapy in paediatric tumours (Dr Thankamma Ajithkumar, Consultant Clinical Oncologist, Cambridge University Hospitals NHS Foundation Trust) 2022-05-12 09:30: Frontiers in paediatric cancer research (Dr Suzannne Turner, Dept of Pathology) 2022-05-19 09:30: Cancer resistance in the naked mole-rat, a tale of transformation (Prof Ewan St John Smith; Dept of Pathology) 2022-05-19 13:00: Cell Plasticity and Lineage Commitment in Liver Tumorigenesis (Lars Zender, University Hospital Tuebingen) 2022-05-26 09:30: Understanding Myc Transcription (Dr Cathy Wilson, Department of Pharmacology) 2022-06-09 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, CRUK Cambridge Institute) 2022-06-16 09:30: CANCELLED The impact of environmental factors on cancer ( Dr Elisabete Silva, Brunel University London) 2022-06-23 09:30: Cell differentiation and tumour initiation - two sides of the coin ( Dr Walid Khaled Dept of Pharmacology/ Cambridge Stem Cell Institute ) 2022-06-30 09:30: Kidney cancer: The most lethal urological malignancy (Prof Grant Stewart, Dept of Surgery, Cambridge University Hospitals NHS Foundation Trust) 2022-07-07 09:30: Pancreatic Cancer: Challenges, Models and Therapeutic Opportunities (Dr Giulia Biffi; Cancer Research UK Cambridge Institute) 2022-07-14 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Muñoz-Espin; Department of Oncology) 2022-07-14 12:00: Mitochondria and Cancer - lessons learned dissecting cellular and molecular interactions (Marica Haigis, Harvard Medical School) 2022-07-21 09:30: Lung Cancer. Part 1. Patient pathway and Intervention; Part 2: Futurescape (Professor Robert Rintoul (Papworth Hospital and Dr Frank McCaughan (Dept of Biochemistry)) 2022-09-15 13:00: This seminar has been cancelled - we apologise for any inconvenience caused. Thank you (Nikolaus Rajewsky, MDC Berlin) 2022-10-13 13:00: Probing the rate limitation of a cancer driver mutation (Hans-Reimer Rodewald, DKFZ) 2022-10-20 09:30: Tumour pathology, structure and nomenclature (Dr. Paul Edwards (University of Cambridge)) 2022-10-27 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2022-11-03 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2022-11-10 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2022-11-17 09:30: Simulating medicine: testing- speculations about medical science and clinical practice (Prof Jacob Stagenga, Department of History and Philosophy of Science: ) 2022-11-17 13:00: This seminar has been cancelled - we apologise for any inconvenience caused. Thank you (Louis Chesler, ICR) 2022-11-24 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology) 2022-12-01 09:30: Cancer metabolism, a hallmark of cancer (Prof Christian Frezza, CECAD Research Center, University Hospital Cologne) 2022-12-08 09:30: DNA repair: translating mechanistic insights towards new cancer therapies. (Prof Steve Jackson; The Gurdon Institute ) 2022-12-08 13:00: Title to be confirmed (Serena Nik-Zainal, MRC Cancer Unit) 2022-12-15 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Muñoz-Espin; Department of Oncology / Early Cancer Institute) 2023-01-12 09:30: The role of transcription factors in cancer. (Prof Jason Carroll, CRUK Cambridge Institute) 2023-01-19 09:30: In vivo functional screens for modelling cancer initiation and progression (Dr Eric Rahrmann, Cancer Research UK Cambridge Institute) 2023-01-26 09:30: The development of cancer risk prediction models and their applications to prevention and early detection ( Prof Antonis Antoniou, Dept of Public Health and Primary Care) 2023-02-02 09:30: Cancer virology (Professor John Doorbar, Department of Pathology) 2023-02-16 09:30: TALK CANCELLED (Prof Rebecca Fitzgerald, Early Cancer Institute) 2023-02-23 09:30: Experimental cancer genetics (Dr David Adams, Wellcome Sanger Institute) 2023-02-23 13:00: Tumor genomes shed light into somatic mutational processes and cancer vulnerabilities (Nuria Lopez-Bigas) 2023-03-02 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, CRUK Cambridge Institute) 2023-03-09 09:30: How do cells acquire drug resistance mutations? (Dr Jon Houseley, Babraham Institute) 2023-03-16 09:30: Immune Regulation in Inflammation and Cancer (Dr Rahul Roychoudhuri) 2023-03-23 09:30: The two hit hypothesis and other simple theories of cancer (Dr Jamie Blundell, Early Cancer Institute) 2023-03-23 13:00: A DNA methylation atlas of normal human cell types (Tommy Kaplan, the Hebrew University of Jerusalem) 2023-03-30 09:30: Artificial Intelligence in Cancer (Dr Michael Boemo, Dept of Pathology) 2023-04-20 09:30: Machine learning: applications to cancer ( Dr Mireia Crispin, Department of Oncology) 2023-04-20 13:00: Stressing out our immune system in chronic infection and cancer (Susan Kaech) 2023-04-27 09:30: Toolkit in Cancer Research: in vitro modelling and spatial phenotyping (Dr John Lizhe Zhuang; Early Cancer Institute and Dept of Oncology) 2023-05-04 09:30: Shedding light on tumour physiology ( Dr Mariam-Eleni Oraiopoulou; research associate VISION Lab CRUK Cambridge Institute ) 2023-05-04 13:00: Small Cell Lung Cancer from biology to biomarkers (Caroline Dive, CRUK Manchester Institute) 2023-05-09 09:30: Kidney cancer (Dr James Jones; Cambridge University Hopitals NHSFT) 2023-05-09 09:30: Kidney cancer (Dr James Jones; Cambridge University Hospitals NHSFT) 2023-05-11 09:30: Understanding Myc Transcription (Dr Catherine Wilson; Dept of Pharmacology) 2023-05-18 09:30: Single cell RNA seq. and application in cancer research (Dr. Walid Khaled and Dr Sara Pensa (Cambridge Stem Cell Institute)) 2023-05-18 13:00: Seminar cancelled (Polly Fordyce, Stanford University) 2023-05-25 09:30: A scientists guide to the art of radiation therapy & Neurosurgery for the oncologist (Dr Raj Jena Dept of Oncology and Cambridge University Hospitals; Mr Adel Helmy, Dept of Clinical Neuroscience) 2023-06-01 09:30: Cancer resistance in the naked mole-rat: tales of transformation and more! ( Prof Ewan St John Smith, Dept of Pharmacology) 2023-06-08 09:30: Biological and Clinical features of high grade serous ovarian cancer (Prof James Brenton, CRUK Cambridge Institute and Cambridge University Hospitals NHSFT) 2023-06-15 09:30: Nutrition and cancer prevention (Prof Martin Wiseman, World Cancer Research Fund International and Visiting Professor in Human Nutrition Southampton University ) 2023-06-15 13:00: Title to be confirmed (Nikolaus Rajewsky) 2023-06-22 09:30: Kidney cancer: an introduction (Dr James Jones; Cambridge University Hopitals NHSFT) 2023-06-29 09:30: The promise of proton therapy in paediatric tumours (Dr Thankamma Ajithkumar, Consultant Clinical Oncologist, Cambridge University Hospitals NHS Foundation Trust) 2023-07-06 09:30: Early stage cancer clinical trials (Dr Simon Pacey, Cambridge University Hospital, Dept of Oncology) 2023-07-13 09:30: Pancreatic Cancer - The clinical challenge; Why the microenvironment matters during progression and treatment (Dr Giulia Biffi and Dr Bristi Basu; CRUK Cambridge Institute / Oncology Dept and Cambridge University Hospitals) 2023-07-20 09:30: Paediatric malignancies (Dr Amos Burke Clinical Consultant, Dept of Paediatric Haematology, Oncology & Palliative Care) 2023-07-27 09:30: Curing cancer with AI – hype or hope? (Prof Richard Gilbertson, CRUK Cambridge Institute and Director of CRUK Cambridge Centre) 2023-09-18 13:00: Updates and opportunities offered by whole genome sequencing on the Cambridge Biomedical Research Campus (Serena Nik-Zainal, Early Cancer Institute, University of Cambridge) 2023-10-02 13:00: How cilia signal (Jeremy Reiter, UCSF) 2023-10-19 09:30: Tumour pathology, structure and nomenclature ( Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2023-10-26 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2023-11-02 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2023-11-06 13:00: First in human evaluation of CDK9 inhibition with KB-0742 in solid tumors (Richard Cutler PhD, Kronos Bio, Inc.) 2023-11-09 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2023-11-16 09:30: Precision oncology: a philosophical perspective (Dr Benjamin Chin-Yee, Haematologist (Western University, Canada); MA in History and Philosophy of Science.) 2023-11-20 13:00: Seminar Cancelled (Karen Vousden) 2023-11-23 09:30: DNA repair: translating mechanistic insights towards new cancer therapies. (Prof Steve Jackson, CRUK Cambridge Institute ) 2023-11-30 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology) 2023-12-07 09:30: Hypoxia, HIFs and cancer (Prof Margaret Ashcroft, Department of Medicine ) 2023-12-14 09:30: Cancer metabolism, a hallmark of cancer (Prof Christian Frezza CECAD Research Center, University Hospital Cologne) 2023-12-14 11:30: Mapping stromal heterogeneity and immunosuppression in breast cancer (Fatima Mechta-Grigoriou) 2024-01-11 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, Cancer Research UK Cambridge Institute ) 2024-01-18 09:30: Cancer Immunology and Immunotherapy (Prof Rahul Roychoudhuri, Department of Pathology) 2024-01-25 09:30: Steroid hormone regulation of cancer immunity ( Dr Bidesh Mahata, Department of Pathology) 2024-02-01 09:30: Redefining metastasis: what we know and where we are going ( Dr Eric Rahrmann, Cancer Research UK Cambridge Institute. ) 2024-02-15 12:00: "Meet the Expert": How to survive and thrive as an entrepreneur (Dr Jason Mellad, Co-Founder and CEO of Startcodon. ) 2024-02-15 13:00: Deciphering Developmental Disorders (Matthew Hurles, Sanger Institute) 2024-02-22 09:30: The development of cancer risk prediction models and their applications to prevention and early detection ( Prof Antonis Antoniou, Department of Public Health and Primary Care. ) 2024-02-29 09:30: Frontiers in paediatric cancer research (Professor Suzanne Turner, Department of Pathology) 2024-03-07 09:30: Fluorogenetic interrogation of epigenetic pathways (Dr Iva Tchasovnikarova, Gurdon Institute and Department of Biochemistry. ) 2024-03-14 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute) 2024-03-21 09:30: Clonal haematopoiesis, early detection and pre-leukemia to leukemia development (Prof Elisa Laurenti, Wellcome-MRC Cambridge Stem Cell Institute. ) 2024-04-11 09:30: Understanding the cancer genome base-by-base (Dr David Adams, Wellcome Sanger Institute) 2024-04-18 09:30: The role of radiation in cancer care: a spotlight on cancers of the oesophagus, head and neck (Dr Gill Barnett; Dept of Oncology and Strangeways Research Laboratory; Dr Christopher Jones, Dept of Oncology and Cambridge University Hospitals ) 2024-04-18 13:00: Towards Rational Combination Therapies: Understanding tumor evolution during therapy response and resistance (Anna Obenauf, IMP Vienna) 2024-04-25 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Munoz Espin, Early Cancer Institute and Dept of Oncology) 2024-05-02 09:30: Biological and clinical insights from genome-wide association studies of cancer (Dr Siddhartha Kar, Early Cancer Institute and Department of Oncology) 2024-05-03 13:00: Modelling and Targeting the Tumour Microenvironment of High-Grade Serous Ovarian Cancer (Professor Frances Balkwill OBE, FMedSci, Centre for Tumour Microenvironment, Barts Cancer Institute, Queen Mary University of London, UK) 2024-05-09 09:30: Cancer resistance in the naked mole-rat: tales of transformation and more! (Prof Ewan St John Smith, Department of Pharmacology) 2024-05-16 09:30: Cancer virology (Prof John Doorbar, Department of Pathology) 2024-05-16 13:00: Title to be confirmed (KJ Patel, MRC WIMM, Oxford) 2024-05-23 09:30: Targeted Protein Degradation tools for novel therapeutic strategies in cancer (Dr Catherine Lindon, Dept of Pharmacology) 2024-05-30 09:30: The two-hit hypothesis and other mathematical models of cancer (Dr Jamie Blundell, Early Cancer Institute and Department of Oncology) 2024-06-06 09:30: TODAY'S TALK CANCELLED DUE TO SICKNESS Machine learning: applications to cancer (Dr Mireia Crispin Ortuzar, Early Cancer Institute and Department of Oncology) 2024-06-13 09:30: Does reconstructing the past history of kidney cancer help predict clinical behaviour? (Dr Tom Mitchell; Early Cancer Institute and Dept of Surgery) 2024-06-20 09:30: Early cancer trials (Dr Simon Pacey, Cambridge University Hospitals, Dept of Oncology) 2024-06-20 14:00: The Biology of Drug Resistance in Lung Cancer (Katerina Politi, Yale School of Medicine) 2024-06-27 09:30: A scientists guide to the art of radiation therapy and Neurosurgery for the oncologist ( Dr Raj Jena, Cambridge University Hospitals and Department of Oncology; Mr Adel Helmy, Department of Clinical Neuroscience) 2024-07-04 09:30: Pancreatic cancer - the clinical challenge;  Why the microenvironment matters during pancreatic cancer progression and treatment (Dr Bristi Basu, Cambridge University Hospitals NHS FT and Dept of Oncology; Dr Giulia Biffi, Cancer Research UK Cambridge Institute) 2024-07-11 09:30: Translating the biology of epigenetics into clinical applications for cancer (Dr Harveer Dev, Early Cancer Institute, Cambridge University Hospitals and Department of Oncology.) 2024-07-18 09:30: Leveraging the Virtuous Cycle: Clinical Trials - Translational Science - Basic Science (Prof Jean Abraham; Director, Cambridge Breast Cancer Research Unit, Cambridge University Hospitals and Department of Oncology) 2024-09-05 13:00: Identifying therapeutic opportunities in the metabolic crosstalk between the tumour and the host (Professor Karen Vousden, The Francis Crick Institute) 2024-10-17 13:00: Senescent secretome shenanigans: Differential therapeutic benefit for breast cancer dictated by distinct extracellular vesicle-mediated inflammatory response (Dr Karen Crasta, Principal Investigator at the National University of Singapore, Centre for Healthy Longevity and Department of Physiology. ) 2024-10-24 09:30: Tumour pathology, structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2024-10-31 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2024-11-07 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2024-11-14 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2024-11-14 13:00: Seminars in Cancer (Andrea Sottoriva, ICR and Human Technopole, Milan) 2024-11-14 13:00: Endogenous Formaldehyde as a driver for clonal haematopoiesis and in pervasive DNA base adduction (Professor KJ Patel, Director of the MRC Molecular Haematology Unit and MRC WIMM at the University of Oxford) 2024-11-21 09:30: Hypoxia, HIFs and cancer (Prof Margaret Ashcroft, Department of Medicine ) 2024-11-28 09:30: DNA repair: translating mechanistic insights towards new cancer therapies. (Prof Sir Steve Jackson, CRUK Cambridge Institute ) 2024-12-05 09:30: Machine learning: applications to cancer (Dr Mireia Crispin Ortuzar, Early Cancer Institute and Department of Oncology) 2024-12-05 13:00: Origins and consequences of gene dosage mutations in cancer (Professor Sam Aparicio, University of British Columbia) 2024-12-12 09:30: Understanding the cancer genome base-by-base (Dr David Adams, Wellcome Sanger Institute) 2024-12-13 13:00: Understanding Mechanisms of Microenvironment-Mediated Therapy Resistance (Professor Michael Hemann, Koch Institute for Integrative Research at MIT) 2024-12-19 09:30: Cancer metabolism, a hallmark of cancer (Prof Christian Frezza CECAD Research Center, University Hospital Cologne) 2025-01-09 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology & Cambridge Stem Cell Institute) 2025-01-16 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, Cancer Research UK Cambridge Institute ) 2025-01-23 09:30: Cancer Immunology and Immunotherapy (Prof Rahul Roychoudhuri, Dept of Pathology) 2025-01-23 13:00: Telomere to mitochondria signaling prevents age-associated cancer initiation (Jan Karlseder, Salk Institute for Biological Studies) 2025-01-30 09:30: Steroid hormone regulation of cancer immunity (Dr Bidesh Mahata, Dept of Pathology) 2025-02-13 09:30: Frontiers in paediatric cancer research (Prof Suzanne Turner; Dept of Pathology) 2025-02-20 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute) 2025-02-27 09:30: Systems immunology and variation in the human immune system (Professor Adrian Liston) 2025-03-06 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Munoz Espin, Early Cancer Institute and Dept of Oncology) 2025-03-13 09:30: Cancer virology (Prof John Doorbar, Department of Pathology) 2025-03-20 09:30: Biological and clinical insights from genome-wide association studies of cancer (Dr Siddhartha Kar, Early Cancer Institute ) 2025-03-20 13:00: Understanding and intercepting somatic clonal evolution in blood (George Vassiliou, CSCI Cambridge) 2025-03-27 09:30: Revealing the Unseen: AI's Role in Novel Target Discovery for High Unmet Needs Areas Through Multi-Omics Integrationce for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities (Dr Namshik Han, Head of Computational Research & AI, Milner Therapeutics Institute) 2025-04-03 09:30: Mutational signatures: From bytes to bedside (Professor Serena Nik-Zainal) 2025-04-10 09:30: Myc in Cancer and Regeneration (Dr Catherine Wilson, Dept of Pharmacology) 2025-04-24 13:00: Homologous recombination deficiency in cancer: prevalence, diagnosis and novel targeting approaches (Simon Powell, MSKCC) 2025-05-01 09:30: Targeted Protein Degradation tools for novel therapeutic strategies in cancer (Dr Catherine Lindon, Dept of Pharmacology) 2025-05-08 09:30: Decoding genomic chaos - a pancancer compendium of chromosomal instability (Professor Florian Markowetz, Cancer Research UK Cambridge Institute) 2025-05-15 09:30: The two-hit hypothesis and other mathematical models of cancer (Prof Jamie Blundell; Early Cancer Institute) 2025-05-22 09:30: Oncogene-induced senescence and tumour initiation (Prof Masashi Narita, Cancer Research UK Cambridge Institute) 2025-05-29 09:30: From lab to clinic: an introduction to translational research (Dr James Jones; Cambridge University Hospitals and Department of Oncology ) 2025-06-05 09:30: Early cancer trials (Dr Simon Pacey, Cambridge University Hospitals, Dept of Oncology) 2025-06-12 09:30: The role of radiation in cancer care: a spotlight on cancers of the oesophagus, head and neck (Dr Gill Barnett and Dr Christopher Jones, Cambridge University Hospital & Dept of Oncology ) 2025-06-19 09:30: Overview of treatment for non-small cell lung cancer (Dr Huiqi Yang and Dr Nicola Thompson, Cambridge University Hopitals Trust) 2025-06-19 13:00: Hope in Hard Places: Bridging the Cancer Care Gap in Resource Limited Settings: Lessons and Innovations from the Uganda Cancer Institute (Dr Nixon Niyonzima, Uganda Cancer Institute) 2025-06-26 09:30: Transmissible cancers (Prof Elizabeth Murchison, Department of Veterinary Medicine. ) 2025-07-03 09:30: The promise of proton therapy in Paediatric tumours (Dr Thankamma Ajithkumar, Cambridge University Hospitals and Department of Oncology. ) 2025-07-10 09:30: Pancreatic cancer - the clinical challenge;  Why the microenvironment matters during pancreatic cancer progression and treatment (Dr Kiran Purushothaman, Cambridge University Hospitals NHS FT and Dept of Oncology; Dr Gianluca Mucciolo CRUK Cambridge Institute (Biffi Lab)) 2025-07-10 13:00: Seminar cancelled - Spatial mapping of breast cancer tumour microenvironment in Black British and White British women (Professor Kairbaan Hodivala-Dilke, Centre for Tumour Microenvironment, 2 Barts Cancer Institute, a Cancer Research UK of Excellence, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK) 2025-07-17 09:30: A scientists guide to the art of radiation therapy and Neurosurgery for the oncologist (Dr Raj Jena and Mr Adel Helmy; Cambridge University Hospitals; Departments of Oncology/ Clinical Nuroscience) 2025-07-24 09:30: Patenting, translating & commercialising research (Prof Rebecca Fitzgerald, Early Cancer Institute and Dept of Oncology) 2025-09-18 13:00: Next generation medicine: towards eliminating the invisible in ovarian cancer (Professor Ahmed Ahmed, University of Oxford) 2025-10-16 13:00: Unique Biology and Clinical Impact in Invasive Lobular Carcinoma (Steffi Oesterreich, University of Pittsburgh) 2025-10-23 09:30: Tumour pathology, structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2025-10-24 14:00: Spatial mapping of breast cancer tumour microenvironment in Black British and White British women (Professor Kairbaan Hodivala-Dilke, Centre for Tumour Microenvironment, Barts Cancer Institute, Queen Mary University of London) 2025-10-30 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2025-11-06 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2025-11-13 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology) 2025-11-20 09:30: Hypoxia, HIFs and cancer (Prof Margaret Ashcroft, Department of Medicine ) 2025-11-20 13:00: Targeting the interplay between oncogenic RAS signaling and tumour immune evasion in lung cancer (Professor Julian Downward, Francis Crick Institute) 2025-11-27 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology & Cambridge Stem Cell Institute) 2025-12-04 09:30: DNA repair: translating mechanistic insights towards new cancer therapies. (Professor Sir Steve Jackson, Cancer Research UK Cambridge Institute) 2025-12-11 09:30: Cancer Immunology and Immunotherapy (Prof Rahul Roychoudhuri, Dept of Pathology) 2025-12-12 13:00: Seminars in Cancer (Andrea Sottoriva, Human Technopole) 2026-01-08 09:30: Cancer metabolism through the lens of Otto Warburg (Prof Christian Frezza CECAD Research Center, University Hospital Cologne) 2026-01-15 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, Cancer Research UK Cambridge Institute ) 2026-01-22 09:30: Systems immunology and variation in the human immune system (Professor Adrian Liston, Dept of Pathology) 2026-01-29 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute) 2026-01-29 13:00: Seminars in Cancer (Santiago Zelenay, CRUK Manchester Institute ) 2026-02-12 09:30: Cancer virology (Prof John Doorbar, Department of Pathology) 2026-02-19 09:30: Frontiers in paediatric cancer research (Prof Suzanne Turner) 2026-02-26 09:30: Machine learning: applications to cancer (Dr Mireia Crispin Ortuzar, Early Cancer Institute and Department of Oncology) 2026-02-26 13:00: A complex TiME: How aging drives tumor progression (Ashani T. Weeraratna, PhD, John Hopkins) 2026-03-05 09:30: The two-hit hypothesis and other mathematical models of cancer (Prof Jamie Blundell; Early Cancer Institute and Department of Oncology) 2026-03-12 09:30: Targeted Protein Degradation tools for novel therapeutic strategies in cancer (Dr Catherine Lindon, Dept of Pharmacology) 2026-03-19 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities. (Dr Daniel Munoz Espin, Early Cancer Institute and Dept of Oncology) 2026-03-26 09:30: Biological and clinical insights from genome-wide association studies of cancer (Dr Siddhartha Kar, Early Cancer Institute and Dept of Oncology) 2026-04-01 09:30: Title to be confirmed (Prof Greg Hannon, Cancer Research UK Cambridge Institute) 2026-04-01 09:30: Title to be confirmed (Prof Greg Hannon, Cancer Research UK Cambridge Institute) 2026-04-16 09:30: Mutational signatures: From bytes to bedside (Prof Serena Nik-Zainal, NIHR Research Professor in Genomic Medicine and Bioinfromatics) 2026-04-16 13:00: Seminars in Cancer (Antoine Molaro, iGReD) 2026-04-23 09:30: Decoding genomic chaos - a pancancer compendium of chromosomal instability (Professor Florian Markowetz, Cancer Research UK Cambridge Institute) 2026-04-30 09:30: From lab to clinic: an introduction to translational research (Dr James Jones; Cambridge University Hospitals and Department of Oncology ) 2026-05-14 09:30: Overview of treatment for non-small cell lung cancer (Dr Huiqi Yang and Dr Nicola Thompson, Cambridge University Hopitals Trust) 2026-05-14 13:00: Seminars in Cancer (Francisco X. Real, CNIO, Madrid) 2026-05-21 09:30: The role of radiation in cancer care: a spotlight on cancers of the oesophagus, head and neck (Dr Gill Barnett; Dept of Oncology; Dr Christopher Jones, Dept of Oncology and Cambridge University Hospitals ) 2026-06-04 09:30: Using Light for Cancer Detection (Dr Danielle Harper; Dept of Oncology and Early Cancer Institute ) 2026-06-11 09:30: Early cancer clinical trials (Dr Simon Pacey, Cambridge University Hospitals, Dept of Oncology) 2026-06-18 09:30: Pancreatic cancer - the clinical challenge;  Why the microenvironment matters during pancreatic cancer progression and treatment (Dr Kiran Purusothaman, CUH and Dept of Oncology; Dr Wenlong Li, Biffi Lab, CRUK Cammbridge Institute) 2026-06-18 13:00: Seminars in Cancer (Tyler Jacks, PhD, Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology) 2026-06-25 09:30: Clonal haematopoiesis, early detection and pre-leukemia to leukemia development (Prof Elisa Laurenti, Cambridge Stem Cell Institute and Dept of Haematology) 2026-07-02 09:30: A scientists guide to the art of radiation therapy and Neurosurgery for the oncologist (Dr Raj Jena and Mr Adel Helmy; Cambridge University Hospitals; Departments of Oncology/ Clinical Nuroscience)