Dementia Journal Club 2018-11-01 14:00: Introductory Journal Club Meeting - Tau filament structures (Veronica and Antonina, CIMR) 2018-11-15 14:00: PET tracers for Tau (Nisha, Stephen, and Selena) 2018-11-29 14:00: Autophagy and neural stem cell therapy; a new tool for dementia (Michele Frison, MRC-MBU) 2018-12-13 14:00: DJC Holiday Networking Event (Speaker to be confirmed) 2019-01-10 14:00: Cofactor-assisted seeding of tau fibrils (Alexander Epstein, LMB) 2019-01-24 14:00: Amyloid-β ‘seeds’ in old vials of growth hormone (Ryan Prestil, CIMR) 2019-02-07 14:00: AD-associated variants identified by whole exome sequencing (Alexander Mörseburg, Department of Archaeology) 2019-03-07 14:00: Leptin and AD risk (Selena Sephton, WBIC) 2019-03-21 14:00: Recognition of the amyloid precursor protein by human γ-secretase (Nathan Zaccai (University of Cambridge)) 2019-04-04 14:00: Blood Brain Barrier breakdown in Neurodegeneration (Helen Boffey & Tim Rooney, DDI) 2019-05-02 14:00: Exploring the amyloid beta secretome in 2D and 3D culture models of AD (Laura Pellegrini (MRC-LMB)) 2019-06-06 14:00: VCAM1, brain ageing, and the 'vampire hypothesis' (Veronica Kane Dickson) 2019-07-25 14:00: Hot science: a peak into the living brain (Nisha Ramakrishnan) 2019-11-21 14:00: Neuroinflammation and gut microbiota in AD progression (Nathan Zaccai (University of Cambridge)) 2019-12-12 14:00: Cryo-EM structures of Aß amyloid fibrils (Veronica Kane Dickson (University of Cambridge)) 2020-01-16 14:00: From gut to brain: An alpha-synuclein Parkinson’s model (Katrina Räty (University of Cambridge)) 2020-02-19 14:00: Cryo-EM structure of alpha-synuclein fibrils (Janin Lautenschläger) 2020-03-26 14:00: Cryo-EM structures of patient-derived alpha-synuclein fibrils - CANCELLED (Manuel Schweighauser - LMB)