University of Cambridge > Talks.cam > MRC LMB Seminar Series > LMB Seminar Series - CryoEM of proton pumping macromolecular machines

  Browse A-Z

Log in

Googledetails Microsoftdetails

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹī¸ Information

LMB Seminar Series - CryoEM of proton pumping macromolecular machines

Download to your calendar using vCal

If you have a question about this talk, please contact Scientific Meetings Co-ordinator .

Electrochemical proton gradients across energized membranes play central roles in numerous cellular processes. These gradients are established by large membrane-embedded protein complexes.V-type ATPasesare responsible for acidification of intracellular compartments including endosomes, lysosomes, the Golgi, and exocytic vesicles. Electron transport chain complexes energize the inner membranes of mitochondria and the plasma membranes of bacteria to drive production of cellular ATP during oxidative phosphorylation. Many of these protein complexes are highly dynamic, complicating their structural analysis. We have isolated a number of these assemblies from bacterial, yeast, and mammalian sources, and examined them by electron cryomicroscopy (cryoEM) to understand their function and regulation. In order to facilitate this process, we also develop new biochemical, specimen preparation, and computational approaches for cryoEM.

This talk is part of the MRC LMB Seminar Series series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Grad Seminar Rm, 3rd Fl. Raised Faculty Bldg., Sidgwick Site. Dixon / Greaves Room, Department of Pathology, Tennis Court Road Jewish History

Other talks

Group Work CSaP Annual Cleevely Lecture 2026 Afternoon Break From lab to clinic: an introduction to translational research Morning Tea and Coffee Polar Oceans Seminar Talk
 

Š 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity