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The genomes of transmissible cancers

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If you have a question about this talk, please contact Samantha Noel .

Transmissible cancers are malignant clonal lineages that survive beyond the deaths of their original hosts by the transfer of living cancer cells between hosts. In mammals, transmissible cancers are known in only two species: dogs and Tasmanian devils. The canine transmissible venereal tumour is a sexually transmitted cancer that manifests as genital tumours and which first arose in a single dog that lived several thousand years ago. Tasmanian devils are marsupial carnivores that are affected by two transmissible facial cancers, both of which are transmitted by biting. I will discuss recent work using genetics to further decipher the origins and evolution of these remarkable long-lived cancer lineages.

This talk is part of the Computational and Systems Biology series.

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