Abstract

Recent advances in the sciences underpinning medicine, and their translation to clinical impact, are transforming our ability to understand and treat human diseases. This one-day meeting will explore emerging areas in which the convergence of fundamental science and translational opportunities promises to shape the futures of medicine.

Programme

09.00-09.15 Introduction to meeting

09.15-10.15 Serena Nik-Zainal, Professor of Genomic Medicine and Bioinformatics, Department of Medical Genetics, School of Clinical Medicine, University of Cambridge – The contribution of genomics to precision medicine

10.15-11.15 Shyni Varghese, Professor of Biomedical Engineering, Mechanical Engineering and Materials Science and Orthopaedics, Duke University, USA - Tissue engineering

11.15-11.45 Morning Coffee

11.45- 12.45 Jan Hoeijmakers, Department of Molecular Genetics, Erasmus University, Rotterdam and Cologne, Princess Maxima Center for Pediatric Oncology, Oncode, Utrecht, both in the Netherlands and the CECAD , Cologne, Germany – DNA damage, cancer and aging, the unexpected impact of nutrition on medicine

12.45-13.45 Lunch

13.45-14.45 Paul Workman, Former CEO and President of the Institute of Cancer (ICR), London, Harrap Professor of Pharmacology and Therapeutics, Centre for Cancer Drug Discovery, ICR – Transforming small molecule cancer drug discovery for precision medicine

14.45-15.45 Iain Buchan, W.H. Duncan Chair in Public Health Systems, Associate Pro Vice Chancellor for Innovation, Public Health, Policy & Systems, University of Liverpool – How might artificial intelligence augment population health?

15.45-16.15 Afternoon Tea

16.15- 17.15 Alessio Ciulli, Professor of Chemical and Structural Biology and Director of the Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee – Proximity-inducing modalities in drug discovery: Protein degraders and beyond

17.15 Closing remarks