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Dr Henry Staines, St. George's Hospital Medical School, London
Wednesday 29 April 2009, 16:30-17:30
Of men and beasts, parasite-altered transmembrane transport
- đ¤ Speaker: Dr Henry Staines, St. George's Hospital Medical School, London
- đ Date & Time: Wednesday 29 April 2009, 16:30 - 17:30
- đ Venue: Lecture Theatre 1, Department of Veterinary Medicine
Abstract
Apicomplexan parasites are an important cause of disease in animals and man but are poorly controlled. Several of these parasites, including Plasmodium and Babesia, reside within the red blood cells of their hosts. During intracellular development the parasites alter the permeability of their host red blood cells. This can contribute to parasite survival by modulating nutrient uptake, waste removal and volume and ion regulation. For these reasons, the transport pathways that underlie this process have been proposed as drug targets and/or selective routes to target the internal parasite. The talk will cover our present understanding of this phenomenon and also cover some recent data derived from Plasmodium-infected liver cells.
Series This talk is part of the Departmental Seminar Programme, Department of Veterinary Medicine series.
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