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Epigenetic profiling reveals mechanisms of microglial reprogramming in models of Alzheimer’s disease pathology

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If you have a question about this talk, please contact Timothy Birkle .

Microglia can modify their molecular and functional phenotypes depending on their past and current microenvironment, including long-term reprogramming that is driven through epigenetic modifications (aka innate immune memory). In my talk, I will discuss our past and current work on how epigenetic analyses can enhance our understanding of the molecular mechanisms that drive microglial responses in the diseased brain.

This talk is part of the Microglia webinar series series.

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