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The investigation of genetic patterns of coronary artery disease within a predictive and a causal perspective

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If you have a question about this talk, please contact Dr Clive Bowsher .

I will discuss the different motivations at the basis of the two above mentioned approaches. I will use causal graphs to explain statistical analysis and interpretation issues arising in both cases, while emphasizing the dangers of an acritical application of regression methods to the problem. I will refer to two ongoing studies: 1) a retro-prospective study based on a sample of 2000 cases of early myocardial infarction, and 2) an ongoing retrospective study to discover genetic patterns of Crohn’s disease. This is work-in-progress, with only preliminary results discussed.

(Joint work with Luisa Bernardinelli)

This talk is part of the Causal Inference Seminar and Discussion Group series.

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