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Using global multicohort studies to determine how genetic and environmental factors influence brain development in infancy and early childhood.

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If you have a question about this talk, please contact Simon Braschi .

In this talk, Dr. Knickmeyer, founder and director of the Organization for Imaging Genomics in Infancy (ORIGINs), will describe who will be included in this dataset, what is being measured, and data analysis plans. She will provide highlights from ORIGI Ns first major analysis in which we mapped the trajectory of intracranial volume (ICV), subcortical structures (Thalamus, Hippocampus, Amygdala, Caudate, Putamen and Pallidum) and cognitive development from birth to six years in over 2000 children from four countries (Germany, Singapore, South Africa, and the US), investigated the effect of sex, preterm birth, birthweight, maternal education, and family income on trajectories of ICV and subcortical volumes and on cognitive development, and examined brain-cognition correlations. She will also present emerging results from a genome-wide association study of CSF -related phenotypes in early infancy and a genome-wide association study of resting-state fMRI phenotypes in early infancy.

This talk is part of the ARClub Talks series.

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Castlereagh Room, Fisher Buidling, St John's College Hoyle Lecture Theatre, IoA (tea at 3:30 pm) Emmanuel College (TBC)

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