Assessing causality in perinatal and developmental epidemiology
- đ¤ Speaker: Professor Debbie Lawlor, University of Bristol, MSc(Lond), MBChB, PhD(Bristol), MPH(Leeds), MRCGP, MFPHM Professor of Epidemiology đ Website
- đ Date & Time: Friday 06 March 2015, 13:00 - 14:00
- đ Venue: Large Seminar Room, 1st Floor, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge
Abstract
Whilst randomised controlled trials in pregnant women and children are not impossible there are added restrictions and difficulties in experiments in these groups. As a result policy and clinical practice is often driven by observational evidence. For example, recent international policy regarding diagnosing gestational diabetes and monitoring weight gain in pregnancy are based on traditional multivariable analyses in observational studies. In this talk I will talk about how causal understanding that this stage in the life course might be improved by triangulating findings from several approaches each of which has differing key sources of bias. The approaches that will be looked at are cross cohort comparisons, negative control studies, matched study designs and Mendelian randomization (the use of genetic variants as instrumental variables).
Series This talk is part of the Bradford Hill Seminars series.
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Professor Debbie Lawlor, University of Bristol, MSc(Lond), MBChB, PhD(Bristol), MPH(Leeds), MRCGP, MFPHM Professor of Epidemiology 
Friday 06 March 2015, 13:00-14:00