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Construction of efficient experimental designs under resource constraints

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Design and Analysis of Experiments

We will introduce “resource constraints” as a general concept that covers many practical restrictions on experimental design, such as limits on budget, time, or available material. To compute optimal or near-optimal exact designs of experiments under multiple resource constraints, we will propose a tabu search heuristic related to the Detmax procedure. To illustrate the scope and performance of the proposed algorithm, we chose the problem of construction of optimal experimental designs for dose escalation studies.

This talk is part of the Isaac Newton Institute Seminar Series series.

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