The structure and logic of axis extension in Drosophila
- đ¤ Speaker: Blanchard, G (University of Cambridge)
- đ Date & Time: Thursday 08 October 2015, 11:00 - 12:30
- đ Venue: Seminar Room 2, Newton Institute Gatehouse
Abstract
Convergence and extension movements are evolutionarily conserved morphogenetic behaviours that elongate tissues in many contexts in animal embryogenesis and organogenesis. Drosophila germ-band extension is a well-studied example that deforms the germ-band epithelium, a thin monolayer of cells tesselating the surface of the ellipsoidal embryo. Extension is driven by the combination of two temporally coordinated mechanisms. A pull from the posterior of the embryo drives extension of the tissue towards the posterior. Meanwhile, a planar polarised distribution of actin and Myosin II motors drives active cell rearrangements within the tissue, driving convergence in the dorso-ventral axis.
Series This talk is part of the Isaac Newton Institute Seminar Series series.
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Blanchard, G (University of Cambridge)
Thursday 08 October 2015, 11:00-12:30