Abstract

Small, sensitive cantilevers are the fundamental component of the Atomic Force Microscope, capable of high resolution imaging of samples of the most disparate origin, from materials science to biology. Yet, their unique properties have led to the development of several extremely important characterization tools, and cantilevers are now used for local stiffness investigations, single molecule force spectroscopy and even as artificial noses and for very precise mass measurements. Furthermore, very recently we have introduced yet another possible application of the unique properties of cantilevers: the nanomotion sensor. In this presentation I will propose an overview of the different uses of these small sensors, with a particular focus on applications with biological or biomedical interest. I will also present the most recent developments of nanomotion analyses on bacteria and mammalian cells, in order to highlight the versatility of these devices and the possibilities that these cantilevers can open in the fields of biology, microbiology, pharmaceuticals, drug testing and development.