LMB Seminar Series - Kinetochore Structure
- đ¤ Speaker: Steve Harrison
- đ Date & Time: Thursday 28 June 2018, 16:00 - 17:00
- đ Venue: Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol
Abstract
The protein/DNA complex known as the kinetochore links chromosomes to the microtubules of the mitotic spindle. The kinetochores of budding yeast cells appear to be elementary, unimodular versions of the multimodule kinetochores of metazoan cells. Most of the 50â80 distinct protein species that make up a yeast kinetochore are organized into well-defined subcomplexes. Prof. Harrison has been studying the structures of these subcomplexes using a diverse set of approaches including cryoEM and X-ray crystallography. In this seminar, he will present the latest advances of his group on the structure, function, and evolution of the kinetochore
Series This talk is part of the MRC LMB Seminar Series series.
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Steve Harrison
Thursday 28 June 2018, 16:00-17:00