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SUMMARY:&quot\;Vectorbuilder: Revolutionising Vector Design &amp\; Custom 
 Cloning&quot\; (25 min seminar)  followed by   &quot\;Advanced Technologie
 s For Rapid Generation Of Custom Designed Animal Models&quot\; (25 min sem
 inar) - Dr Matthew Wheeler\; Associate Director\, Cyagen
DTSTART:20180215T130000Z
DTEND:20180215T140000Z
UID:TALK100279@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:2x 25 minute seminars\n\n \n\nVectorBuilder: Revolutionising V
 ector Design and Custom Cloning (25 min Seminar) -\nThe only reason clonin
 g is not outsourced is because of cost and a need for communicating the pr
 ecise details of each individual vector design for the experimental purpos
 e. With VectorBuilder\, this is no longer a problem. I will introduce and 
 perform a live demo of VectorBuilder (www.vectorbuilder.com). VectorBuilde
 r is a revolutionary new online tool that not only allows you to create yo
 ur custom vectors with ease but also allows you to simply order them withi
 n minutes at competitive prices and rapid turnaround times. With over 110\
 ,000 vectors already delivered\, Vectorbuilder offers:\n\n• Plasmids\n
 • Lentivirus\n• Adenovirus\n• AAV (adeno associated virus)\n• Tet-
 on/off\n• CRISPR\n• Cre-lox\n• Massive collections of ORFs\n• Tiss
 ue-specific promoters\n• Add tags/reporters/drug-selectable markers\n•
  Virus packaging - Lenti\, Adeno\, AAV\, MMLV \n• BAC modification\n• 
 Library construction\n\n \n\nAdvanced Technologies For Rapid Generation Of
  Custom-Designed Animal Models For Your Research (25 min Seminar) - \nWhil
 e the generation of transgenic mouse and rat models clearly provides inval
 uable insights into human disease\, the process of generating transgenic a
 nimals is often complicated\, time-consuming and costly. Cyagen (www.cyage
 n.com) is the world’s leading provider of custom-designed transgenic mic
 e and rats offering a one-stop solution to all your animal needs. To date\
 , we have delivered over 18\,500 animal models. \n\nIn this seminar\, I wi
 ll provide an overview of the current State-of-the-art as well as draw on 
 own academic experience to give an overview of our technologies including:
 \n·         PiggyBac transgenic mice and rats - single copy transgene int
 egration\n·         TurboKnockout® - ES cell targeted cKO/KI mice in 6-8
  months\n·         CRISPR-mediated genome editing – Knockouts/knockins 
 (Up to 8Kb)
LOCATION:Babraham - The Cambridge Building\; Kings Hedges Room
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