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SUMMARY:Cellular recycling: role of autophagy in aging and disease - Profe
 ssor Malene Hansen\; Sanford Burnham Prebys Medical Discovery Institute\, 
 Program for Development\, Aging and Regeneration\, La Jolla\, CA\, USA
DTSTART:20180405T120000Z
DTEND:20180405T130000Z
UID:TALK100855@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:The cytosolic recycling process of autophagy plays an importan
 t role in many age-related diseases and has been directly linked to aging\
 , including in the nematode C. elegans where autophagy appears beneficiall
 y induced in many conserved longevity models. As a critical process to ens
 ure cellular homeostasis\, autophagy is regulated at multiple levels\, yet
  it remains a challenge in the field to understand how the regulation of a
 utophagy is integrated at the cellular and molecular level to ensure healt
 h- and lifespan benefits. I will here discuss our progress on understandin
 g the different molecular mechanisms employed by cells and organisms to re
 gulate autophagy in response to stressors such as aging and disease.
LOCATION:Babraham - The Cambridge Building\; Kings Hedges &amp\; Queen Edi
 th Combined Rooms
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