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SUMMARY:Talk title: Microfluidic devices for blood analysis - Debjani Paul
 \, Department for Biosciences and Bioengineering\, Indian Institute of Tec
 hnology Bombay\, INDIA
DTSTART:20180302T160000Z
DTEND:20180302T170000Z
UID:TALK102109@talks.cam.ac.uk
CONTACT:Lorenzo Di Michele
DESCRIPTION:Physical properties of cells\, such as\, size\, shape and defo
 rmability have recently generated a lot of interest as potential biomarker
 s for different diseases. For example\, infection by the malarial parasite
 s makes the infected red blood cells (RBCs) stiffer. Normally biconcave an
 d deformable RBCs become sickle-shaped and stiffer in sickle cell anemia\,
  thereby leading to vaso-occlusion in capillaries. My research group uses 
 microfluidic technology to probe physical properties of cells to diagnose 
 different blood-related disorders. In this talk I will briefly discuss two
  of our ongoing projects. The first project involves quantifying the shape
  change of red blood cells to detect sickle cell disease at the point of c
 are. The second project describes a pillar-based microfluidic device to so
 rt cells from whole blood. The final goal of both these projects is to dev
 elop portable and affordable microfluidic devices to bring disease diagnos
 tics from the hospitals to the patient’s bedside. 
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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