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SUMMARY:Sailing close to the wind of psychotic fire-a dopaminergic journey
  - Dr Sameer Jauhar\, Senior Research Fellow\, King's College\, London
DTSTART:20181101T123000Z
DTEND:20181101T133000Z
UID:TALK108559@talks.cam.ac.uk
CONTACT:Nicholas Morgan
DESCRIPTION:In this talk I wish to discuss findings from a group of PET st
 udies I have conducted over the last 5 years\, examining the presynaptic d
 opamine system\, in healthy volunteers (pharmacological challenge) and fir
 st episode psychosis. \n\nRelevant papers from these studies are below.\n	
 \n \n1. Jauhar S\, Veronese M\, Rogdaki M\, Bloomfield M\, Natesan S\, Tur
 kheimer F\, et al. Regulation of dopaminergic function: an [18F]-DOPA PET 
 apomorphine challenge study in humans. Transl Psychiatry. 2017 Feb 7\;7(2)
 :e1027. \n2. Jauhar S\, Nour MM\, Veronese M\, Rogdaki M\, Bonoldi I\, Azi
 s M\, et al. A Test of the Transdiagnostic Dopamine Hypothesis of Psychosi
 s Using Positron Emission Tomographic Imaging in Bipolar Affective Disorde
 r and Schizophrenia. JAMA Psychiatry. 2017 Oct 11\;74(12):1206–13. \n3. 
 Jauhar S\, Veronese M\, Nour MM\, Rogdaki M\, Hathway P\, Turkheimer FE\, 
 et al. Determinants of treatment response in first-episode psychosis: an 1
 8 F-DOPA PET study. Molecular Psychiatry. 2018 Apr 20\;1. \n4. Jauhar S\, 
 Veronese M\, Nour MM\, Rogdaki M\, Hathway P\, Natesan S\, et al. The Effe
 cts of Antipsychotic Treatment on Presynaptic Dopamine Synthesis Capacity 
 in First-Episode Psychosis: A Positron Emission Tomography Study. Biol Psy
 chiatry. 2018 Jul 11\; \n5. Jauhar S\, McCutcheon R\, Borgan F\, Veronese 
 M\, Nour M\, Pepper F\, et al. The relationship between cortical glutamate
  and striatal dopamine in first-episode psychosis: a cross-sectional multi
 modal PET and magnetic resonance spectroscopy imaging study. The Lancet Ps
 ychiatry. 2018 Oct 1\;5(10):816–23. \n
LOCATION:Seminar Room\, Herchel Smith Building\, Forvie Site.
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