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SUMMARY:Role of Mitogen Activated Protein Kinase cascade during light and 
 submergence signaling in plants - Professor Alok Krishna Sinha
DTSTART:20180802T100000Z
DTEND:20180802T110000Z
UID:TALK108568@talks.cam.ac.uk
CONTACT:15150
DESCRIPTION:The mitogen activated protein kinase (MAPK/MPK) cascade is kno
 wn to regulate several stress responses and developmental processes in euk
 aryotes. The cascade usually consists of three tier component comprising o
 f MAPK\, MAPK kinase (MAPKK/ MAP2K/ MKK) and MAPKK kinase (MAPKKK/ MAP3K/ 
 MKKK). All these three components are connected to each other by an event 
 of phosphorylation. Upon activation MAPK phosphorylates various cytosolic 
 and nuclear proteins for appropriate cellular readjustment. The role of th
 is cascade will be discussed in light signal transduction pathway during s
 eedling development in Arabidopsis and submergence tolerance in rice. In A
 rabidopsis the activation and interaction of AtMPK6 with MYC2 transcriptio
 n factor was observed to be blue light (BL) dependent. AtMKK3 was identifi
 ed as an upstream kinase of AtMPK6 in the same pathway. The role of MYC2 h
 as been deciphered as a negative regulator of blue light signaling in Arab
 idopsis. In rice we identified regulation of SUB1A1 specifically by OsMPK3
 . SUB1AI is one of the genes of SUBMERGENCE1 (SUB1) quantitative trait loc
 us that confers submergence tolerance up to two weeks in certain varieties
  of rice. SUB1A1 was identified as an interacting partner as well as phosp
 horylation target of OsMPK3 in a submergence dependent manner. We propose 
 a positive feedback loop that governs SUB1A1 interaction with MPK3 and imp
 acts on submergence tolerance in rice.
LOCATION:Tom ap Rees\, Department of Plant Sciences
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