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SUMMARY:Think Global Act Local: do local morphological changes influence d
 ifferentiation of pluripotent cells? - Dr Sally Lowell from Centre for Reg
 enerative Medicine\, University of Edinburgh  
DTSTART:20190502T130000Z
DTEND:20190502T140000Z
UID:TALK109285@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:We are interested in the mechanisms that make early developmen
 t robust and reproducible in the face of fluctuating or imprecise signals.
  As pluripotent tissues move towards differentiation they experience morph
 ological rearrangements that are driven by changes in cell adhesion. We wi
 ll present evidence that these changes modulate the ability of pluripotent
  cells to respond to extrinsic cues. This tells us that changes in cell ad
 hesion and morphology are not simply a passive consequence of differentiat
 ion\, but rather that they actively feed back into the decision making pro
 cess.  
LOCATION:Biffen Lecture Theatre\, Department of Genetics\, Downing Site
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