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SUMMARY:Discovering the gene networks that regulate hunger - Dr Katherine 
 Lawler (MRC Institute of Metabolic Science)
DTSTART:20181107T140000Z
DTEND:20181107T150000Z
UID:TALK111562@talks.cam.ac.uk
CONTACT:46925
DESCRIPTION:Abstract: Obesity and its co-morbidities are an emerging publi
 c health concern. The detailed mechanistic understanding of energy balance
  and the development of obesity is currently incomplete. The Genetics of O
 besity Study (GOOS) recruited thousands of individuals with early-onset ex
 treme childhood obesity. This study led to the identification of rare gene
 tic variants affecting key processes in the hypothalamus\, a part of the b
 rain involved in weight regulation and energy balance. To gain further ins
 ights our current work encompasses the genetics of severe obesity and the 
 genetics of thinness. We combine large genomic data sets from different po
 pulations and platforms with detailed clinical information related to thin
 ness and severe obesity to discover new pathways involved in weight regula
 tion and associated diseases.
LOCATION:MR4\,  Centre for Mathematical Sciences\, Wilberforce Road\, Camb
 ridge
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