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SUMMARY:Computational Neuroscience Journal Club - Rodrigo Echeveste (CBL)
DTSTART:20181016T150000Z
DTEND:20181016T160000Z
UID:TALK113026@talks.cam.ac.uk
CONTACT:Rodrigo Echeveste
DESCRIPTION:Rodrigo Echeveste will present:\n\n• Neural implementation o
 f Bayesian inference in a sensorimotor behavior\n\n• Timothy R. Darlingt
 on\, Jeffrey M. Beck and Stephen G. Lisberger\n\n• Nature Neuroscience (
 2018)\n\n• https://www.nature.com/articles/s41593-018-0233-y/\n\n\nAbstr
 act: Actions are guided by a Bayesian-like interaction between priors base
 d on experience and current sensory evidence. Here we unveil a complete ne
 ural implementation of Bayesian-like behavior\, including adaptation of a 
 prior. We recorded the spiking of single neurons in the smooth eye-movemen
 t region of the frontal eye fields (FEFSEM)\, a region that is causally in
 volved in smooth-pursuit eye movements. Monkeys tracked moving targets in 
 contexts that set different priors for target speed. Before the onset of t
 arget motion\, preparatory activity encodes and adapts in parallel with th
 e behavioral adaptation of the prior. During the initiation of pursuit\, F
 EFSEM output encodes a maximum a posteriori estimate of target speed based
  on a reliability-weighted combination of the prior and sensory evidence. 
 FEFSEM responses during pursuit are sufficient both to adapt a prior that 
 may be stored in FEFSEM and\, through known downstream pathways\, to cause
  Bayesian-like behavior in pursuit.\n
LOCATION:Cambridge University Engineering Dept.\, Board Room (2nd floor\, 
 Baker building)
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