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SUMMARY:Udderly different?: A comparative approach to studying the mammary
  gland in health and disease. - Dr Kate Hughes\, Department of Veterinary 
 Medicine\, University of Cambridge
DTSTART:20190206T160000Z
DTEND:20190206T170000Z
UID:TALK114145@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:“Udderly different?”: A comparative approach to studying t
 he mammary gland in health and disease.\n\nThe mammary gland undergoes con
 siderable postnatal development\, with epithelial proliferation\, and late
 r remodelling\, occurring in parallel with pregnancy\, lactation\, and sub
 sequent post-lactational involution. Remarkably\, this cycle of developmen
 t and regression can occur many times with successive pregnancies. The mam
 mary gland is susceptible to both inflammation (mastitis) and neoplastic t
 ransformation\, and these pathological processes may intersect with the gl
 and’s postnatal developmental cycle. Much of our knowledge regarding mam
 mary pathology\, and particularly the role of the Signal Transducers and A
 ctivators of Transcription (STAT) family in coordinating mammary gland dev
 elopment\, is derived from the study of laboratory mice. Such studies have
  resulted in a detailed understanding of the regulation of the mammary pos
 tnatal cycle\, but to what extent is this knowledge transferable to domest
 ic species\, particularly ruminants\, and the study of farm animal mastiti
 s?\n\n\n\n
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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