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SUMMARY:The Evolutionary Genomics of Staphylococcus aureus Infections - Pr
 of Daniel Wilson\, Big Data Institute\, University of Oxford
DTSTART:20190213T160000Z
DTEND:20190213T170000Z
UID:TALK114286@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:Like other major bacterial pathogens\, S. aureus asymptomatica
 lly colonizes the human body far more frequently than it causes severe inf
 ections. This raises the question of what are the evolutionary and genetic
  differences between infection and asymptomatic colonization? To address t
 his question we have sequenced and analysed S. aureus genomes to chart evo
 lution within hundreds of healthy and infected patients\, and to discover 
 genetic differences associated with bacteria infecting and colonizing thou
 sands of unrelated cases and controls. These studies reveal surprising dif
 ferences in the genetic basis of different types of infection\, and reveal
  signatures of bacterial adaptation within the human body to selection pre
 ssures that are as yet incompletely understood.\n
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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