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SUMMARY:Organic bioelectronics: addressing the interface challange - Dr Da
 mia Mawad\, Senior Lecturer\, UNSW Sydney
DTSTART:20190108T140000Z
DTEND:20190108T150000Z
UID:TALK116536@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:Bioelectronics is considered the future of medicine as it is n
 ot only contributing to the basic\nunderstanding of biological systems but
  also to clinical diagnostics and therapeutics through\ntissue-electronics
  interfaces. A major challenge facing their successful medical application
 s is\nthe development of compatible and functional interface technologies 
 that enable biological to\nelectronic signal transduction. This central co
 nsideration is driving the “rise of organic\nbioelectronics” [1]. Crit
 ical to this rise has been the incorporation of conjugated polymers\n(CPs)
  as the electrically active component. CPs are soft\, flexible and mechani
 cally tunable\;\nthus more compatible with tissue than inorganic electroni
 cs.\nThe attractive properties of CPs have largely been demonstrated in in
  vitro applications while\ntheir in vivo application is limited to coating
 s for inorganic electrodes to allow for more\nintimate electronic contact 
 between the device and the tissue [2]. Examples of the challenges\nthat ha
 ve been hindering the translation into the complex physiological environme
 nt include\nelectronic stability and integration with the host tissue. A l
 ack of versatile chemistries for\nfunctional CPs underpin these challenges
 . By manipulating the chemistry of CPs and\nemploying controlled design st
 rategies\, we develop novel bioelectronics with the aim to\naddress the af
 orementioned limitations [3-6].\n[1] Rivnay\, J.\, Owens\, R. M. & Malliar
 as\, G. G. Chem. Mater. 26\, 679–685 (2014).\n[2] Martin\, D. C. MRS Com
 mun. 5\, 131–153 (2015).\n[3] Mawad\, D. et al. Chem. Mater. 28\, 6080
 –6088 (2016).\n[4] Jiang\, L. et al. ACS Appl. Mater. Interfaces 9\, 441
 24–44133 (2017).\n[5] Mawad\, D. et al. Sci. Adv. 2\, e1601007 (2016).\n
 [6] Cui\, C. et al. Biomater. Sci. 6\, 493–500 (2018).
LOCATION:Electrical Engineering\, Department of Engineering - Seminar Room
  - 9 JJ Thomson Avenue\, Cambridge\, CB3 0FA
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