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SUMMARY:LMB Seminar Series - Perutz Lecture - The enigmatic TMEM16 family 
 - Lily Jan\, Jack and DeLoris Lange Professor of Molecular Physiology at t
 he University of California at San Francisco (UCSF) and the Howard Hughes 
 Medical Institute (HHMI)
DTSTART:20190919T150000Z
DTEND:20190919T160000Z
UID:TALK116662@talks.cam.ac.uk
CONTACT:72112
DESCRIPTION:The mammalian TMEM16 (TransMEMbrane proteins with unknown func
 tion 16) family has ten members with diverse functions\, including calcium
 -activated chloride channels (TMEM16A/B)\, an auxiliary subunit of sodium-
 activated potassium channel (TMEM16C)\, and a calcium-activated cation cha
 nnel and lipid scramblase (TMEM16F). I will present our recent studies of 
 these TMEM16 family members.\n\nLily Jan went to California Institute of T
 echnology (Caltech) for graduate school\, after finishing her college stud
 y at National Taiwan University in 1968. She and her husband Yuh Nung Jan 
 began their long-term collaboration when they were postdoctoral fellows\, 
 first with Seymour Benzer at Caltech and then with Steve Kuffler at Harvar
 d Medical School. After joining the University of California\, San Francis
 co (UCSF) faculty in 1979\, Lily and Yuh Nung Jan began their ion channel 
 studies with molecular identification of voltage-gated potassium channels\
 , inward rectifier potassium channels\, and calcium-activated chloride cha
 nnels\, in order to study these channels one at a time\, to learn how they
  work and what they do in neurons and other cell types.\n
LOCATION:Max Perutz Lecture Theatre\, Medical Research Council (MRC) (MRC 
 Laboratory of Molecular Biol
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