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SUMMARY:Power law rheology of complex fluids - Dr Alexandre Kabla (CUED\, 
 University of Cambridge)
DTSTART:20190315T130000Z
DTEND:20190315T140000Z
UID:TALK117664@talks.cam.ac.uk
CONTACT:Joseph Ibrahim
DESCRIPTION:Cell migration and cell mechanics play a crucial role in a num
 ber of key biological processes\, such as embryo development or cancer met
 astasis. Understanding the way cells control their own material properties
  and mechanically interact with their environment is key. At a more fundam
 ental level\, there is need better measure\, describe and monitor cell and
  tissue mechanics before we can formulate testable hypotheses.\n\nIn this 
 talk\, I will report experimental studies on the mechanical response of tw
 o different multicellular structures: epithelial monolayers and early embr
 yonic tissues. In both cases\, the material exhibits a strong time-dependa
 nt response over a broad distribution of time-scales. The combination of m
 echanical characterisation with biological perturbations offers new insigh
 t into the mechanisms exploited by cells and tissue to control their mecha
 nical properties.\n\nThis insight is however limited by the lack of consis
 tency in experimental protocols and modelling strategies used in the field
 . We recently developed a systematic approach to capture material properti
 es from mechanical behaviours and made progress assessing the model’s ge
 nerality over a broad range of biological systems.
LOCATION:JDB Seminar Room\, CUED
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