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SUMMARY:Morphogenesis is stressful -  The challenges of measuring tension 
 in a 3D dynamic cell sheet - Stephanie Höhn (University of Cambridge)
DTSTART:20190207T130000Z
DTEND:20190207T140000Z
UID:TALK119797@talks.cam.ac.uk
CONTACT:Anne Herrmann
DESCRIPTION:Living tissues are intelligent materials that can change their
  mechanical properties while they develop. In spite of extensive studies i
 n multiple model organisms we are only just beginning to understand these 
 dynamic properties and their role in tissue development. Although many tis
 sues are known to exhibit visco-elastic properties\, it is unclear which p
 roperties dominate three-dimensional shape changes of cellular monolayers\
 , such as epithelia. The inversion process in Volvox serves as model syste
 m for morphogenetic shape changes of cell sheets. During inversion an init
 ially spherical cell sheet gradually adopts a mushroom shape through inwar
 ds folding (invagination) at the equator and contraction of the posterior 
 hemisphere. Laser ablation is used to cut the cell sheet in order to deter
 mine the elastic properties in different regions and at different stages o
 f inversion.
LOCATION:MR11\, Centre for Mathematical Sciences\, Wilberforce Road\, Camb
 ridge
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