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SUMMARY:Micro Electron Diffraction in a Cryo Electron Microscope: A powerf
 ul tool for protein and small molecule structure determination - Dr Abhay 
 Kotecha\, Materials and Structural Analysis Division\, Thermo Fisher Scien
 tific\, Eindhoven\, The Netherlands
DTSTART:20190227T110000Z
DTEND:20190227T120000Z
UID:TALK120913@talks.cam.ac.uk
CONTACT:Andrzej Szewczak-Harris
DESCRIPTION:In this talk I will show how we can use electron cryo-microsco
 pe (CryoEM) to collect electron diffraction from micro- and nano-crystals 
 yielding high-resolution protein structures in a quick and easy way with M
 icroED method. MicroED can bypass the hurdles of crystal size and radiatio
 n damage allowing for the use of extremely small crystals for protein and 
 small molecule structure determination at atomic resolution. \nMicroED als
 o gives researchers the opportunity to characterize newly synthesized comp
 ounds “on the fly\,” meaning they can gather important details about a
  sample throughout its creation\, potentially guiding the chemical develop
 ment process. This is an exciting time for electron crystallographers and 
 those who would like to use micro and nanocrystals. There is much work to 
 be done improving and optimizing this technique\, however\, we are current
 ly working on testing and automating the workflow to make microED fast and
  easy\, and easily accessible to all users.\n
LOCATION:Department of Biochemistry\, Sanger Building Jean Thomas Lecture 
 Theatre
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