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SUMMARY:Nucleosomal Asymmetry Shapes Histone Mark Binding at Bivalent Doma
 ins - Dr Philipp Voigt\; Sir Henry Dale Fellow\, Wellcome Centre for Cell 
 Biology\, University of Edinburgh
DTSTART:20190614T110000Z
DTEND:20190614T120000Z
UID:TALK121888@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:Philipp Voigt is a Sir Henry Dale Fellow at the Wellcome Centr
 e for Cell Biology. Work in his lab aims to determine how different histon
 e modifications interact to regulate gene expression in embryonic stem cel
 ls\, focusing on Polycomb and trithorax group protein complexes. His lab i
 s taking a multidisciplinary approach\, combining biochemistry with proteo
 mic\, genomic\, cell-biological\, and systems biology-inspired techniques.
  Philipp received both his undergraduate and graduate degree in Biochemist
 ry from Freie Universität Berlin\, Germany. His PhD work focused on phosp
 hoinositide kinase signalling pathways in lymphocytes. In 2008\, he joined
  the laboratory of Danny Reinberg at NYU School of Medicine\, New York\, f
 or his postdoctoral studies. There\, he studied molecular mechanisms of Po
 lycomb-mediated gene silencing\, revealing that sister histones within sin
 gle nucleosomes can carry different histone modifications in an asymmetric
  fashion. He moved to Edinburgh in November 2014 to start his own research
  group as a Sir Henry Dale Fellow and ERC Starting Grant holder.
LOCATION:Babraham - The Cambridge Building - Kings Hedges Room
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