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SUMMARY:Canine Babesiosis: selected aspects of the topic - Prof. Stanislaw
  Winiarczyk\, University of Life Sciences\, Faculty of Veterinary Medicine
 \, Lublin\, Poland
DTSTART:20190508T150000Z
DTEND:20190508T160000Z
UID:TALK123553@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:Babesiosis is caused by a haemotropic protozoal parasite of th
 e genus Babesia\, member of the phylum Apicomplexa and transmitted by the 
 bite of an infected tick. Canine babesiosis in Europe is generally caused 
 by Babesia canis and Babesia gibsoni. Clinically\, both species cause remi
 ttent fever\, progressive anemia\, hemoglobinuria\, and marked splenomegal
 y and hepatomegaly in dogs and\, in some cases\, the death of infected ani
 mals. Mostly\, the clinical\ncases of the disease are reported in spring a
 nd autumn and are associated with the seasonal activity of vectors of Babe
 sia. Demonstration of parasites in the blood collected from a carrier anim
 al by blood smear examination is an absolute and reliable method of diagno
 sis of canine babesiosis. Nonetheless\, molecular methods\, such as polyme
 rase chain reaction(PCR)\, present a higher sensitivity and specificity th
 an the peripheral blood smear evaluation to detect and characterize babesi
 al infection in peripheral blood. Furthermore\, they may differentiate spe
 cies that cannot be morphologically distinguished by smear method. However
 \, these methods may also present false-negative results of blood tests\, 
 if the parasites accumulate in the spleen\, for instance. Therefore\, mass
  spectrometry (MS)-based proteomics analyses offer new approaches to ident
 ify biomarkers for the detection of disease.\n
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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