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SUMMARY:DENdrimicelles Dendrimer-Encapsulated-Nanoparticle coacervate-core
  Micelles - Prof. Dr. Aldrik Velders (Wageningen University &amp\; Researc
 h)
DTSTART:20190508T130000Z
DTEND:20190508T140000Z
UID:TALK124144@talks.cam.ac.uk
CONTACT:Lingtao Kong
DESCRIPTION:Coacervate-core micelles constitute an important class of nano
 aggregates\, typically in the range of 50 – 100 nanometer\, that are of 
 interest for their application in material and biomedical sciences. We hav
 e developed a strategy to obtain insight in the formation\, stability and 
 properties of micelles\, exploiting 5-10 nanometer PAMAM Dendrimer-Encapsu
 lated Nanoparticles (DENs) as the core-building block\, hence coined DENdr
 imicelles. The electron-dense nanoparticles allow for straightforward anal
 ysis by cryo-TEM of these hierarchical nanostructures over multiple length
  scales. Cryo-TEM of the DENdrimicelles provides insight in the periodicit
 y of different generations of used dendrimers\, the aggregation number of 
 the corresponding micelles\, insight in the core-properties\, details on m
 esoscale organization\, and surprising aspects on stability of thin-layers
 .\n\nReferences. [1] Gomez\, M. V.\; Guerra\, J.\; Myers\, V. S.\; Crooks\
 , R. M.\; Velders\, A. H. J. Am. Chem. Soc. 2009\, 131\, 14634. [2] Gomez\
 , M. V.\; Guerra\, J.\; Velders\, A. H.\; Crooks\, R. M. J. Am. Chem. Soc.
  2009\, 131\, 341– 350 [3] Ten Hove\, J. B.\; Wang\, J.\; van Leeuwen\, 
 F. W. B.\; Velders\, A. H. Nanoscale\, 2017\, 11\, 18619. [4] Ten Hove\, J
 . B.\; Wang\, J.\; van Oosterom\, M.\; van Leeuwen\, F. W. B.\; Velders\, 
 A. H. ACS Nano\, 2017\, 11225. [5] Ten Hove\, J. B.\; van Oosterom\, M. N.
 \; van Leeuwen\, F. W. B.\; Velders\, A. H. Sci. Rep.\, 2018\, 13820. [6] 
 ten Hove\, J. B.\; van Leeuwen\, F. W. B.\; Velders\, A. H. Nat. Commun.\,
  2018\, 5207.\n
LOCATION:PfizerLecture Theatre\,  Department of Chemistry\, Lensfield Road
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