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SUMMARY:Fibrillar protein self-assembly from a materials science and biome
 dical point of view - Prof. Tuomas Knowles\, Department of Chemistry\, Cam
 bridge
DTSTART:20191018T140000Z
DTEND:20191018T150000Z
UID:TALK126481@talks.cam.ac.uk
CONTACT:Yonatan Calahorra
DESCRIPTION:This talk describes our efforts at elucidating the physical pr
 inciples that control the self-assembly of protein molecules into fibrilla
 r structures. Such assemblies are involved in biological function and malf
 unction\, and are commonly held together with extended beta sheets when th
 ey are known as amyloid fibrils. These species were first discovered in th
 e context of protein aggregation diseases. It has recently become apparent
 \, however\, that they also possess a multitude of functional roles in nat
 ure. Inspired by these natural roles of protein fibrillar materials\, we h
 ave also focused our efforts into tailoring the self assembly of peptide a
 nd proteins to generate artificial functional materials.
LOCATION: Department of Chemical Engineering and Biotechnology Charles Bab
 bage Road\, Cambridge\, Cambridgeshire CB3 0AS
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