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SUMMARY:Collagen mechanics: from basic understanding to clinical applicati
 ons	 - Dr Michelle Oyen\, Department of Engineering
DTSTART:20081001T101500Z
DTEND:20081001T104500Z
UID:TALK12809@talks.cam.ac.uk
CONTACT:Duncan Simpson
DESCRIPTION:Collagen is the ubiquitous structural protein that totals appr
 oximately 25% of the protein in humans. Because of its importance in load-
 bearing tissues\, such as bone\, cartilage\, and ligament\, collagen has i
 ncreasingly been the focus of biomechanical research in the last three dec
 ades. As technology has developed\, studies have diminished in characteris
 tic length-scale to emphasize molecular effects of both self-assembly and 
 mechanical performance\, and how these molecular characteristics relate to
  macroscopic performance of collagen-containing tissues. In this talk\, se
 veral different projects within connective tissue biomechanics will be dis
 cussed\, for which the common theme is collagen. Emphasis will be placed o
 n the links between basic science understanding of collagen structure-func
 tion relationships and the clinical application of this understanding trea
 tment of disease\, design of repair strategies and even measures for preve
 ntion of disruption in collagenous tissues.
LOCATION:MR2\, Centre for Mathematical Sciences\, Wilberforce Road\, Cambr
 idge
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