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SUMMARY:Multiscale approaches to modelling vascular tumour growth - Helen 
 Byrne\, University of Oxford
DTSTART:20200228T160000Z
DTEND:20200228T170000Z
UID:TALK132559@talks.cam.ac.uk
CONTACT:Diana Fusco
DESCRIPTION:Understanding how vascular networks deliver nutrients and chem
 otherapy to solid tumours\, how these networks evolve and how they may be 
 manipulated to improve patient outcomes remain a major focus of cancer res
 earch. Such knowledge is important accurately to predict a tumour’s resp
 onse to radiotherapy and for establishing whether a particular patient’s
  response can be enhanced by treatment with vascular targeting agents.  Ma
 thematical and computational models have the potential to provide valuable
  insight into the biophysical mechanisms that regulate tumour blood flow\,
  transport and vascular remodelling\, and a variety of models have been pr
 oposed. In this talk\, I will explain how integrating data from in vitro a
 nd in vivo experiments within multiscale computational models can be used:
  (i) to propose new mechanisms for tumour hypoxia\, and (ii) to characteri
 se the morphology of vascular networks. 
LOCATION:Ryle Seminar (Rutherford 930)
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