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SUMMARY:Complexities and uncertainties of neuronal network analyses - Dr. 
 David Parker (Department of Physiology Development and Neuroscience)
DTSTART:20081023T130000Z
DTEND:20081023T132500Z
UID:TALK13263@talks.cam.ac.uk
CONTACT:Duncan Simpson
DESCRIPTION:We know a lot about the nervous system at the molecular\, cell
 ular\, and synaptic levels: conversely\, we can quantify behaviours and id
 entify the regions of the nervous system correlated with their expression.
  However\, between these levels there is an explanatory gap that prevents 
 us from explaining behaviours in terms of their underlying cellular mechan
 isms. Over the last four decades analyses in a range of systems have attem
 pted to close this gap\, and the minimum criteria that need to be satisfie
 d have been highlighted. However\, despite claims to the opposite\, direct
  links between cellular and synaptic properties and behaviours remain unce
 rtain. If anything\, further analyses have identified cellular and synapti
 c effects that go beyond the traditional criteria and move us further away
  from understanding how cellular interactions generate network outputs and
  behaviours. I will outline the traditional approaches to network analyses
 \, how high profile claims to understanding fail to satisfy these criteria
 \, and how even if they were satisfied these criteria alone would not be s
 ufficient to explain network function.
LOCATION:Kaetsu Centre\, New Hall
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