BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Approaches to wearable microfluidic sensor devices for real-time p
 atient monitoring and personalised well-being. - Professor Martyn Boutelle
 \, Professor of Biomedical Sensors Engineering at Imperial College London.
DTSTART:20191108T110000Z
DTEND:20191108T120000Z
UID:TALK134398@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:Tissue functions at a cellular level by exchange of molecules 
 between cells and blood or between the cells themselves. This produces pat
 terns of molecular change that are diagnostic of cellular processes. The o
 rigin of these molecular changes can be physiological (exhaustion) or path
 ological (injury\, renal failure\, cancer). Our monitoring technologies ha
 ve now developed to a point where we can aspire to do more than single poi
 nt-of-care measurement\, to measure from patients in real-time. The has th
 e great benefit that it is then possible to understand the evolution of di
 sease\, the effectiveness of treatments\, and ultimately to guide treatmen
 t.\nIn this presentation I will describe the development of biosensor-base
 d microfluidic devices connected to wireless electronics for monitoring of
  the injured human brain in the intensive care unit\, transplant organs in
  transit\, and athlete monitoring. Tissue sampling is via an integrated mi
 crofluidic device\, a microdialysis probe. Molecular biomarkers are measur
 ed using microscale integrated amperometric biosensors and solid-contact i
 on-selective electrodes (ISE) for tissue ionic balance. For detailed patte
 rns of ionic responses we have developed high density Field Effect Transis
 tor (FET) array which function as ISEs within the flow stream. We have als
 o developed multiphase flow microfluidic systems for highest time resoluti
 on. The presentation with describe the design and optimization challenges 
 and include clinical examples from our recent work.\n
LOCATION:Electrical Engineering\, Department of Engineering - EED Seminar 
 Room - 9 JJ Thomson Avenue\, Cambridge\, CB3 0FA
END:VEVENT
END:VCALENDAR