BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Subpopulations and Stability in Microbial Communities - Pierre Haa
 s (University of Cambridge)
DTSTART:20191107T130000Z
DTEND:20191107T140000Z
UID:TALK134410@talks.cam.ac.uk
CONTACT:Anne Herrmann
DESCRIPTION:In microbial communities\, each species has multiple\, distinc
 t phenotypes\, but studies of ecological stability have largely ignored th
 is subpopulation structure. Here\, we show that simple models with subpopu
 lation structure and their averages without subpopulations generically giv
 e contradictory linear stability results. We analyse the effect of phenoty
 pic switching in detail in the asymptotic limit of the bacterial persister
  phenotype and partly overturn classical stability paradigms: abundant phe
 notypic variation is linearly destabilising but\, surprisingly\, a rare ph
 enotype has a stabilising effect. Finally\, we extend these results by sho
 wing numerically how phenotypic variation modifies the stability of the sy
 stem to large perturbations such as antibiotic treatments.\n
LOCATION:MR14\,  Centre for Mathematical Sciences\, Wilberforce Road\, Cam
 bridge
END:VEVENT
END:VCALENDAR