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SUMMARY:Getting to the root of developmental networks - Professor Philip B
 enfey\, Duke University
DTSTART:20081113T160000Z
DTEND:20081113T170000Z
UID:TALK13481@talks.cam.ac.uk
CONTACT:3901
DESCRIPTION:Specification and maintenance of cell identity are central pro
 cesses of development. In an effort to understand the regulatory networks 
 that control cell identity\, we have profiled all cell types and developme
 ntal stages within a single organ\, the Arabidopsis root. To acquire globa
 l expression profiles we developed technology that uses sorted marked popu
 lations of cells with subsequent hybridization of the labelled RNA to micr
 oarrays. We are using computational methods to infer networks functioning 
 within different cell types and developmental stages and have begun to tes
 t the hypothesized relationships. Our current efforts are aimed at underst
 anding the responses to environmental stimuli at high spatio-temporal reso
 lution. We are developing new expression analysis platforms and means of a
 nalyzing 4-D data sets. We are also analyzing the dynamics of growth of ph
 ysical root networks using novel non-invasive imaging methods and developi
 ng mathematical descriptors of network architecture.\n\nhttp://www.biology
 .duke.edu/benfeylab/philip.htm
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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