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SUMMARY:Of Form and Function: Assembly of Visual Circuits in Vertebrates -
  Professor Robert Hindges
DTSTART:20191212T110000Z
DTEND:20191212T120000Z
UID:TALK135340@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:One of the fundamental challenges in Neuroscience is to unders
 tand the underlying mechanisms that ensure specificity of connections betw
 een neurons. Visual information is processed already in the retina and spl
 it into different information channels before it is transmitted to higher 
 visual centres in the brain. Such channels are represented through neurons
  belonging to individual circuits and serve therefore as excellent models 
 to study specificity. We have recently identified the molecular and cellul
 ar components crucial for the detection of oriented or elongated visual st
 imuli. Our results show that specific synaptic adhesion molecules are resp
 onsible to set up the retinal connectivity within this circuit. Furthermor
 e\, the structure and overall arborisation shape of retinal inhibitory neu
 rons involved is directly linked to their functionality\, thereby creating
  orientation selectivity. The talk will give an overview of our findings r
 elating structure to function and present the vertebrate visual system as 
 a model for cell type-specific connectivity.
LOCATION:Electrical Engineering\, Department of Engineering - EED Seminar 
 Room - 9 JJ Thomson Avenue\, Cambridge\, CB3 0FA
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