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SUMMARY:Anhedonia and Adolescent Depression - Dr Ciara McCabe\, Associate 
 Professor of Neuroscience\, University of Reading
DTSTART:20200131T163000Z
DTEND:20200131T180000Z
UID:TALK135895@talks.cam.ac.uk
CONTACT:Louise White
DESCRIPTION:abstract: \n\nAdolescence is a period of change that crucially
  increases vulnerability to depression. Studies report blunted neural resp
 onses to reward that relate to positive affect and depression symptoms in 
 adolescents. However how these results relate to the symptom of anhedonia 
 in adolescents is not entirely clear.\nWe have been examining how the brai
 n responds to reward and aversion in those at risk of depression and adole
 scents with depression and anhedonia symptoms.\nWe use an fMRI task measur
 ing the different components of reward and aversion processing such as the
  anticipation and consummation of reward. More recently we have also begun
  to measure effort for reward as a proxy for motivational deficits in depr
 ession.\nOur work shows that there are blunted brain responses to reward a
 nd aversion in adolescents with symptoms of depression. We also find there
  is reduced physical effort for reward in those with symptoms compared to 
 controls. Finally we also show how the dimensional experience of anhedonia
  correlates with neural responses and effort for reward and aversion in ad
 olescents.\nWe discuss the shortcomings of the current literature on anhed
 onia in adolescent depression and suggest how the links between the experi
 ence of anhedonia in adolescent depression and the behavioural and neural 
 measures of reward could be improved.\n\n\nBiblio: Ciara McCabe is an Asso
 ciate Professor of Neuroscience at the University of Reading (Head: Neuroi
 maging of Reward Group: NRG). She examines human reward dysfunction in dep
 ression and the effects of antidepressant treatments on the neural respons
 e to reward.  In 2008 she was awarded a British Association of Psychopharm
 acology\, (BAP) Lilly Fellowship and in 2010 she was awarded a European Co
 llege of Neuropsychopharmacology (ECNP) Fellowship Award in Amsterdam. In 
 2012 she was awarded The International College of Neuropsychopharmacology 
 (CINP) Rafaelsen Young Investigator’s Award\, as part of the biannual me
 eting in Stockholm. In 2014 she received a University of Reading Celebrati
 ng Success Award. Ciara also received an In‐vivo Training Initiative Awa
 rd from the BAP in 2014 and 2015. Ciara has recently received the Senior N
 on‐ Clinical Psychopharmacology Award from BAP in 2015. Ciara is active 
 in public engagement and has appeared on TV (Channel 4 Dispatches and BBC1
 ) and on Radio talking about her work on depression. She has also appeared
  in print (e.g. The Guardian). In 2014 she spoke at the Cheltenham Science
  Festival and the Institute of Physics Public Lecture series and will talk
  at SciBar in Oxford\, Cafe Scientific in Reading and at the University of
  Reading Public Lecture series in 2015 about her work on the neurobiology 
 of depression and anti‐depressant treatment.\n
LOCATION:Ground Floor Lecture Theatre\, Department of Psychology
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